Idan Shalev
Assistant Professor of Biobehavioral Health
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223 Biobehavioral Health Building
University Park, PA 16802 - ius14@psu.edu
- 814-863-7256
Research Summary
Interdisciplinary approach to identify mechanisms underpinning the biological embedding of stress across the lifespan with a special focus on biological aging.
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Publication Tags
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Telomere Health Leukocytes Dna Methylation Caloric Restriction Psychiatry Mental Disorders Research Prospective Studies Biomarkers Confidence Intervals Longevity Puberty Erosion Public Health Schools Anxiety Disorders Oxytocin Receptors Mental Disorder Post Traumatic Stress Disorders Psychological Stress Genes Asthma Sexual Violence Parturition Sex OffensesMost Recent Publications
Cross-tissue comparison of telomere length and metrics of DNA integrity, quality, and quantity among individuals aged 8 to 70 years
Sarah Wolf, Waylon Hastings, Qiaofeng Ye, Laura Etzel, Abner Apsley, Christopher Chiaro, Christine Heim, Thomas Heller, Jennie Noll, Hannah Schreier, Chad Shenk, Idan Shalev, PLOS One
Cross-tissue comparison of telomere length and quality metrics of DNA among individuals aged 8 to 70 years
Sarah E. Wolf, Waylon J. Hastings, Qiaofeng Ye, Laura Etzel, Abner T. Apsley, Christopher Chiaro, Christine C. Heim, Thomas Heller, Jennie G. Noll, Hannah M.C. Schreier, Chad E. Shenk, Idan Shalev, 2024, PLoS One
Effect of long-term caloric restriction on telomere length in healthy adults: CALERIE™ 2 trial analysis
Waylon J. Hastings, Qiaofeng Ye, Sarah E. Wolf, Calen P. Ryan, Sai Krupa Das, Kim M. Huffman, Michael S. Kobor, William E. Kraus, Julia L. MacIsaac, Corby K. Martin, Susan B. Racette, Leanne M. Redman, Daniel W. Belsky, Idan Shalev, 2024, Aging Cell
Affective reactivity to daily stressors and immune cell gene expression in the MIDUS study
Abner T. Apsley, Sun Ah Lee, Aarti C. Bhat, Jonathan Rush, David M. Almeida, Steven W. Cole, Idan Shalev, 2024, Brain, Behavior, and Immunity on p. 80-88
Early origins of health and disease risk: The case for investigating adverse exposures and biological aging in utero, across childhood, and into adolescence
Laura Etzel, Patricia Garrett-Petters, Idan Shalev, 2023, Child Development Perspectives on p. 149-156
The shelterin protein expansion of telomere dynamics: Linking early life adversity, life history, and the hallmarks of aging
Sarah E. Wolf, Idan Shalev, 2023, Neuroscience and Biobehavioral Reviews
Telomere length and chronological age across the human lifespan: A systematic review and meta-analysis of 414 study samples including 743,019 individuals
Qiaofeng Ye, Abner T. Apsley, Laura Etzel, Waylon J. Hastings, John T. Kozlosky, Cade Walker, Sarah E. Wolf, Idan Shalev, 2023, Ageing Research Reviews
Author Correction: Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (Nature Aging, (2023), 3, 3, (248-257), 10.1038/s43587-022-00357-y)
R. Waziry, C. P. Ryan, D. L. Corcoran, K. M. Huffman, M. S. Kobor, M. Kothari, G. H. Graf, V. B. Kraus, W. E. Kraus, D. T.S. Lin, C. F. Pieper, M. E. Ramaker, M. Bhapkar, S. K. Das, L. Ferrucci, W. J. Hastings, M. Kebbe, D. C. Parker, S. B. Racette, I. Shalev, B. Schilling, D. W. Belsky, 2023, Nature Aging on p. 753
Biological stability of DNA methylation measurements over varying intervals of time and in the presence of acute stress
Abner T. Apsley, Qiaofeng Ye, Laura Etzel, Sarah Wolf, Waylon J. Hastings, Brooke C. Mattern, Sue Rutherford Siegel, Idan Shalev, 2023, Epigenetics
Investigating the effects of maltreatment and acute stress on the concordance of blood and DNA methylation methods of estimating immune cell proportions
Abner Apsley, Laura Etzel, Waylon J. Hastings, Christine C. Heim, Jennie G. Noll, Kieran J. O’Donnell, Kieran O'Donnell, Hannah Schreier, Chad E. Shenk, Qiaofeng Ye, Idan Shalev, 2023, Clinical Epigenetics
Most-Cited Papers
The p factor: One general psychopathology factor in the structure of psychiatric disorders?
Avshalom Caspi, Renate M. Houts, Daniel W. Belsky, Sidra J. Goldman-Mellor, Honalee Harrington, Salomon Israel, Madeline H. Meier, Sandhya Ramrakha, Idan Shalev, Richie Poulton, Terrie E. Moffitt, 2014, Clinical Psychological Science on p. 119-137
Internalizing disorders and leukocyte telomere erosion: A prospective study of depression, generalized anxiety disorder and post-Traumatic stress disorder
I. Shalev, T. E. Moffitt, A. W. Braithwaite, A. Danese, N. I. Fleming, S. Goldman-Mellor, H. L. Harrington, R. M. Houts, S. Israel, R. Poulton, S. P. Robertson, K. Sugden, B. Williams, A. Caspi, 2014, Molecular Psychiatry on p. 1163-1170
Change in the rate of biological aging in response to caloric restriction: Calerie Biobank analysis
Daniel W. Belsky, Kim M. Huffman, Carl F. Pieper, Idan Shalev, William E. Kraus, Rozalyn Anderson, 2018, Journals of Gerontology - Series A Biological Sciences and Medical Sciences on p. 4-10
Oxytocin receptor and vasopressin receptor 1a genes are respectively associated with emotional and cognitive empathy
F. Uzefovsky, I. Shalev, S. Israel, S. Edelman, Y. Raz, D. Mankuta, A. Knafo-Noam, R. P. Ebstein, 2015, Hormones and Behavior on p. 60-65
Childhood Sexual Abuse and Early Timing of Puberty
Jennie G. Noll, P Trickett, J Long, S Negriff, E Susman, Idan Shalev, J Li, F Putnam, 2017, Journal of Adolescent Health on p. 65-71
Comparability of biological aging measures in the National Health and Nutrition Examination Study, 1999–2002
Waylon J. Hastings, Idan Shalev, Daniel W. Belsky, 2019, Psychoneuroendocrinology on p. 171-178
Perinatal complications and aging indicators by midlife
Idan Shalev, Avshalom Caspi, Antony Ambler, Daniel W. Belsky, Simon Chapple, Harvey Jay Cohen, Salomon Israel, Richie Poulton, Sandhya Ramrakha, Christine D. Rivera, Karen Sugden, Benjamin Williams, Dieter Wolke, Terrie E. Moffitt, 2014, Pediatrics on p. e1315-e1323
Is chronic asthma associated with shorter leukocyte telomere length at midlife?
Daniel W. Belsky, Idan Shalev, Malcolm R. Sears, Robert J. Hancox, Hona Lee Harrington, Renate Houts, Terrie E. Moffitt, Karen Sugden, Benjamin Williams, Richie Poulton, Avshalom Caspi, 2014, American Review of Respiratory Disease on p. 384-391
Early-life stress and reproductive cost: A two-hit developmental model of accelerated aging?
Idan Shalev, Jay Belsky, 2016, Medical Hypotheses on p. 41-47
Contextual adversity, telomere erosion, pubertal development, and health: Two models of accelerated aging, or one?
Jay Belsky, Idan Shalev, 2016, Development and Psychopathology on p. 1367-1383