News

A team of researchers from Penn State and the University of Illinois Chicago has been awarded a grant from the U.S. National Science Foundation to employ biomedical research, clinical data, advanced artificial intelligence and mathematical modeling methods to ultimately support personalized medicine for people with Alzheimer’s disease. The team at Penn State includes Wenrui Hao, professor of mathematics and director of the Center for Mathematical Biology; Rui Zhang, assistant professor of computer science and engineering; and Wenpeng Yin, assistant professor of computer science and engineering. Credit: Penn State. Creative Commons

Can digital replicas of patients help personalize Alzheimer’s treatment?

New NSF grant supports project to build 'digital twin' replicas of patients using clinical data to study disease progression and treatment options.

Researchers typically have to watch recordings of children in eating studies, like the one this child and research assistant are participating in, to count and time each bite.  Credit: Provided by Kathleen Keller. All Rights Reserved.

Counting bites with AI might one day help prevent childhood obesity

An interdisciplinary team at Penn State published a pilot study demonstrating the potential of using AI to streamline research on obesity risk in children.

Clive Randall, Evan Pugh University Professor of Materials Science and Engineering, has been elected as a fellow of the European Academy of Sciences. Credit: Seana Wood / Penn State. Creative Commons

Clive Randall elected as fellow of the European Academy of Sciences

Clive Randall, Evan Pugh University Professor of Materials Science and Engineering, has been elected as a fellow of the European Academy of Sciences.

From left: Joy Bergelson, Arturo Casadevall, and Martin Wiedmann will present as keynote speakers at the 2026 One Health Microbiome Symposium. Credit: Joy Bergelson, Arturo Casadevall, Martin Wiedmann. All Rights Reserved.

One Health Microbiome Center announces 2026 symposium, keynote speaker lineup

The One Health Microbiome Center (OHMC) in the Penn State Huck Institutes of the Life Sciences will host the One Health Microbiome Symposium on May 13 and 14, 2026.

Wild lupine, a plant of conservation concern across most of its natural range in eastern North America, grows along a Pennsylvania roadside. Credit: Isabella Petitta. All Rights Reserved.

Wild lupine genetics could be key to conservation of species

Researchers at Penn State studying declining populations of sundial lupines in the eastern part of the United States are closer to determining how the plant's genetics could be used to inform reseeding strategies to help with conservation efforts of the blue flowering plant.

The on-skin sensing platform, developed by a team led by researchers at Penn State, can detect vitamin B6 in small concentrations of sweat. The sensor also has the capability to be adapted for glucose sensing at a high sensitivity, allowing patients with diabetes to monitor glucose and vitamin B6 simultaneously. Credit: Provided by Larry Cheng . All Rights Reserved.

Highly sensitive monitor can detect vitamin B6, glucose in sweat

The on-skin sensing platform, developed by a team led by researchers at Penn State, can detect vitamin B6 in small concentrations of sweat. The sensor also has the capability to be adapted for glucose sensing at a high sensitivity, allowing patients with diabetes to monitor glucose and vitamin B6 simultaneously.

Morels, like this yellow or common morel, Morchella esculentoides, were one of the two most often collected wild mushroom species by respondents to the researchers' survey, with 13% reporting that they harvest them. Credit: Penn State. Creative Commons

Wild mushrooms harvesters in Mid-Atlantic region collect fungi, build community

Researchers see the emergence of ‘digital mycology community,’ as mushroom foragers seek guidance and band together into groups online to further their knowledge.

New research helps explain why disease-associated genetic variants can lead to variable clinical outcomes, influenced both by the patterns of secondary variants, or genetic background, and by how cohorts of individuals in a study are ascertained. In a family, shown on left, secondary variants can influence the severity of clinical outcomes, which is indicated by intensity of blue shading, or which features are present between a parent and a child that both carry the primary variant. However, this relationship between secondary and primary variants is different if the primary variant was discovered in a biobank that includes mostly healthy individuals, in the middle, or people identified for a shared clinical feature, on right. Credit: Corrine Smolen/Girirajan Laboratory / Penn State. Creative Commons

Background genetic variants influence clinical features in complex disorders

New study reveals how the complex interplay of genetic background can lead to different clinical presentations in individuals that share a primary genetic variant.

Wenrui Hao, professor of mathematics, was named director of the Center for Mathematical Biology. Credit: Penn State. Creative Commons

Center for Mathematical Biology appoints new director

Wenrui Hao, professor of mathematics in the Penn State Eberly College of Science and 2025-26 Huck Leadership Fellow, has been named the new director for the Center for Mathematical Biology in the Huck Institutes of the Life Sciences.

Core facilities open house welcomes new researchers

More than 120 researchers attended the first-ever Huck Core Facilities Open House last month, which featured informational posters, opportunities to talk with facilities staff, and even some interactive demonstrations.