Center For Structural Oncology News | Center for Structural Oncology

Liquid-Cell Electron Tomography (LC-ET) offers an exciting technical advance to study dynamic materials in solution. The figure illustrates how LC-ET was used to define the “rules of engagement” for pathogenic phages and its host bacterium. IMAGE: KELLY LAB/PENN STATE

Oct 14, 2019

Scientists have first 3D view of life's processes in liquid

A new liquid-cell technology allows scientists to see living biological materials and systems in three dimensions under an electron microscope, according to researchers at Penn State, Virginia Tech and Protochips Inc.

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Deb Kelly’s research team in the department of biomedical engineering and the Center for Structural Oncology at Penn State is developing a new Cryo-EM-On-a-Chip approach. This new technology permits researchers to see the genetic faults within the depths of cancer cells, including those from the brain. Illustration credit: Daryl Branford and Deb Kelly/Penn State

Apr 19, 2019

Advances In Cryo-EM Materials May Aid Cancer And Biomedical Research

Cryogenic-Electron Microscopy (cryo-EM) has been a game changer in the field of medical research, but the substrate used to freeze and view samples under a microscope hasn’t advanced much in decades. Now, thanks to a collaboration between Penn State researchers and the applied science company Protochips, Inc., this is no longer the case.

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Deborah Kelly will continue her revolutionary, cross-disciplinary research at Penn State starting in January 2019.

Nov 08, 2018

Biomedical engineering welcomes pioneering cancer, cryo-electron microscopy researcher

Deborah Kelly, a ground-breaking researcher who developed the new field of structural oncology, will join the University’s Department of Biomedical Engineering as full professor and Lloyd and Dottie Foehr Huck Chair in Molecular Biophysics. Kelly will also hold a joint appointment with the Huck Institutes of Life Sciences and will serve as the director of the new Center for Structural Oncology (CSO) at Penn State.

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