News

Nanoscale ‘computer’ controls function of protein, influences cell behavior

The creation of nanoscale computers for use in precision health care has long been a dream of many scientists and health care providers. Now, for the first time, researchers at Penn State have produced a nanocomputing agent that can control the function of a particular protein that is involved in cell movement and cancer metastasis.

Radioactive metals for medicine get a boost from recently discovered protein

A protein can be used to recover and purify radioactive metals such as actinium that could be beneficial for next-generation drugs used in cancer therapies and medical imaging, according to new research from Penn State and Lawrence Livermore National Laboratory (LLNL).

Modifying RNA: Crucial steps for adding chemical tag to transfer RNA revealed

The chemical steps in an important cellular modification process that adds a chemical tag to some RNAs have been revealed in a new study. Interfering with this process in humans can lead to neuronal diseases, diabetes, and cancers.

Squire Booker named inaugural fellow of the American Society for Biochemistry and Molecular Biology

Squire J. Booker, Evan Pugh Professor of Chemistry and of Biochemistry and Molecular Biology at Penn State, holder of the Eberly Family Distinguished Chair in Science, and investigator with the Howard Hughes Medical Institute, has been named an inaugural fellow of the American Society for Biochemistry and Molecular Biology.

New antibiotic clears multi-drug resistant gonorrhea in mice in single dose

A new antibiotic compound clears infection of multi-drug resistant gonorrhea in mice in a single oral dose, according to a new study led by researchers at Penn State and Emory University.

Three from Eberly College of Science awarded 2021 Sloan Research Fellowships

Three faculty members from the Eberly College of Science have been honored with 2021 Alfred P. Sloan Research Fellowships in recognition of their research accomplishments. The new Sloan fellows include Maria del Carmen Carmona Benitez, assistant professor of physics; Joseph Cotruvo Jr., Louis Martarano Career Development Professor of Chemistry; and Elizabeth Elacqua, assistant professor of chemistry.

Regulating the ribosomal RNA production line

Cryo-electron microscopy study allows researchers to visualize structural changes in an E. coli enzyme synthesizing ribosomal RNA that shift it between turbo- and slow-modes depending on the bacteria’s growth rate

Synthesis of potent antibiotic follows unusual chemical pathway

Images of a protein involved in creating a potent antibiotic reveal the unusual first steps of the antibiotic’s synthesis. The improved understanding of the chemistry behind this process, detailed in a new study led by Penn State chemists, could allow researchers to adapt this and similar compounds for use in human medicine.

Mapping a trail of chemical reactions, Howard Hughes Investigator Squire Booker shows how one group of enzymes helps us stay healthy

Mapping a trail of chemical reactions, Howard Hughes Investigator Squire Booker shows how one group of enzymes helps us stay healthy

Developing a novel oral antibiotic to treat multidrug-resistant gonorrhea

Up to $2.86M has been awarded to a research team including Penn State scientists to develop a new oral antibiotic to treat multidrug-resistant gonorrhea, a sexually transmitted disease caused by bacteria that have developed resistance to all but one existing antibiotic.