Faculty

Leslie Parent

Professor of Medicine and Microbiology & Immunology

H175 Hershey Medical Center
Hershey, PA

Email ljp5@psu.edu
Phone 717-531-7199

Areas of Expertise

Ribonucleic Acid Immunology and Microbiology
Rous Sarcoma Virus Keyphrases
Pregenomic RNA (pgRNA) Keyphrases
Rous Sarcoma Virus Immunology and Microbiology
Gag Protein Keyphrases
RNA Biochemistry, Genetics and Molecular Biology
Retrovirus Keyphrases
Human Immunodeficiency Virus 1 Immunology and Microbiology

Cutaneous clues to a fungal culprit
Paddy Ssentongo, Sarah Akhtar, Zinaida Perciuleac, Courtland Kaye, Rekha Aley Cherian, Elizabeth Garrett, Shirley Albano-Aluquin, Thomas N. Helm, Leslie J. Parent, 2026, In: Frontiers in Medicine
Date: 2026

Dynamic interactions of retroviral Gag condensates with nascent viral RNA at transcriptional burst sites
Rebecca J. Kaddis Maldonado, Leslie J. Parent, Sep 10 2025, In: mBio
Date: Sep 10 2025

Imaging Retroviral RNA Genome Heterodimers Using Bimolecular Fluorescence Complementation (BiFC)
Eunice C. Chen, Rebecca K. Maldonado, Leslie J. Parent, Aug 2025, In: Viruses
Date: Aug 2025

Two Peas in a Pod
Gregory S. Lambert, Christopher A. Siedlecki, Leslie J. Parent, Jun 2025, In: International journal of molecular sciences
Date: Jun 2025

Death From Infection Among Patients Living With Cancer
Mckenzee Chiam, Kyle Mani, Xi Wang, Ming Wang, Daniel M. Trifiletti, Leslie J. Parent, Daniel E. Spratt, Leila Tchelebi, Nicholas Zaorsky, 2025, In: American Journal of Clinical Oncology: Cancer Clinical Trials
Date: 2025

Role of the Psi Packaging Signal and Dimerization Initiation Sequence in the Organization of Rous Sarcoma Virus Gag-gRNA Co-Condensates
Gregory S. Lambert, Rebecca J.Kaddis Maldonado, Leslie J. Parent, Jan 2025, In: Viruses
Date: Jan 2025

Comparative analysis of retroviral Gag-host cell interactions
Gregory S. Lambert, Breanna L. Rice, Rebecca J.Kaddis Maldonado, Jordan Chang, Leslie J. Parent, Dec 2024, In: Retrovirology
Date: Dec 2024

ESCRT Protein VPS4A Is Required for the Formation of Replication Centers and Replication of Human Coronavirus 229E (HCoV-229E)
Rinki Kumar, Rebecca Kaddis Maldonado, Neil Christensen, Maria C. Bewley, John Flanagan, Nicholas Buchkovich, Leslie Parent, Sep 2024, In: COVID
Date: Sep 2024

Effects of ACE inhibitor/ARB therapy and long COVID on kidney disease
Yue Zhang, Djibril M. Ba, Kathryn Risher, Duanping Liao, Leslie J. Parent, Nasrollah Ghahramani, Vernon M. Chinchilli, Jul 1 2024, In: Clinical Kidney Journal
Date: Jul 1 2024

HIV-1 Gag co-localizes with euchromatin histone marks at the nuclear periphery
Jordan Chang, Leslie J. Parent, Dec 2023, In: Journal of virology
Date: Dec 2023

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Identification of a membrane-binding domain within the ammo-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids
Wenjun Zhou, Leslie J. Parent, John W. Wills, Marilyn D. Resh, Apr 1994, In: Journal of virology
Citations: 486

Positionally independent and exchangeable late budding functions of the rous sarcoma virus and human immunodeficiency virus Gag proteins
L. J. Parent, R. P. Bennett, R. C. Craven, T. D. Nelle, N. K. Krishna, J. B. Bowzard, C. B. Wilson, B. A. Puffer, R. C. Montelaro, J. W. Wills, Sep 1995, In: Journal of virology
Citations: 246

SARS-CoV-2 vaccine effectiveness against infection, symptomatic and severe COVID-19
Paddy Ssentongo, Anna E. Ssentongo, Navya Voleti, Destin Groff, Ashley Sun, Djibril M. Ba, Jonathan Nunez, Leslie J. Parent, Vernon M. Chinchilli, Catharine I. Paules, Dec 2022, In: BMC Infectious Diseases
Citations: 220

Equine infectious anemia virus utilizes a YXXL motif within the late assembly domain of the Gag p9 protein
Bridget A. Puffer, Leslie J. Parent, John W. Wills, Ronald C. Montelaro, 1997, In: Journal of virology
Citations: 197

Durational aspects of the oral-pharyngeal phase of swallow in normal adults
Barbara C. Sonies, Leslie J. Parent, Kathleen Morrish, Bruce J. Baum, Mar 1988, In: Dysphagia
Citations: 149

Vancomycin-resistant Staphylococcus aureus in the absence of vancomycin exposure
Cynthia J. Whitener, Sarah Y. Park, Fred A. Browne, Leslie J. Parent, Kathleen Julian, Bülent Bozdogan, Peter C. Appelbaum, Jasmine Chaitram, Linda M. Weigel, John Jernigan, Linda K. McDougal, Fred C. Tenover, Scott K. Fridkin, Apr 15 2004, In: Clinical Infectious Diseases
Citations: 137

Characterization of a daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus strain in a patient with endocarditis
Kathleen Julian, Klaudia Kosowska-Shick, Cynthia Whitener, Martin Roos, Harald Labischinski, Aileen Rubio, Leslie Parent, Lois Ednie, Laura Koeth, Tatiana Bogdanovich, Peter C. Appelbaum, Sep 2007, In: Antimicrobial agents and chemotherapy
Citations: 118

Disseminated mycobacterium marinum infection and bacteremia in a child with severe combined immunodeficiency
Leslie J. Parent, Marguerite M. Salam, Peter C. Appelbaum, John H. Dossett, Nov 1995, In: Clinical Infectious Diseases
Citations: 115

Nuclear entry and CRM1-dependent nuclear export of the Rous sarcoma virus Gag polyprotein
Lisa Z. Scheifele, Rachel A. Garbitt, Jonathan D. Rhoads, Leslie J. Parent, Mar 19 2002, In: Proceedings of the National Academy of Sciences of the United States of America
Citations: 105

Distinct binding interactions of HIV-1 Gag to Psi and non-Psi RNAs
Joseph A. Webb, Christopher P. Jones, Leslie J. Parent, Ioulia Rouzina, Karin Musier-Forsyth, Aug 2013, In: RNA
Citations: 80

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Centers & Institutes

Elsevier Pure Profile

Credit: Keith Hickey / Penn State. Creative Commons

July 15, 2025

Leslie Parent

Areas of Expertise

Optical tweezers help elevate single-molecule research at Penn State

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