Anthony Schmitt
Professor of Molecular Immunology and Infectious Diseases
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220 ASI Building
University Park, PA 16802 - aps13@psu.edu
- 814-863-6781
Research Summary
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.
Huck Affiliations
Links
Most Recent Publications
Strain-Level Identification and Analysis of Avian Coronavirus Using Raman Spectroscopy and Interpretable Machine Learning
Peng Jin, Yin Ting Yeh, Jiarong Ye, Ziyang Wang, Yuan Xue, Na Zhang, Shengxi Huang, Elodie Ghedin, Huaguang Lu, A Schmitt, Anthony Schmitt, H Lu, Sharon Huang, M Terrones Maldonado, Mauricio Terrones, 2023,
RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis
Lara Rheinemann, Diane Miller Downhour, Kate Bredbenner, Gaelle Mercenne, Kristen A. Davenport, Phuong Tieu Schmitt, Christina R. Necessary, John McCullough, Anthony P. Schmitt, Sanford M. Simon, Wesley I. Sundquist, Nels C. Elde, 2021, Cell on p. 5419-5431.e16
Paramyxovirus-like particles as protein delivery vehicles
Santosh Panthi, Phuong Tieu Schmitt, F. Jeffrey Lorenz, Brent A. Stanfield, Anthony P. Schmitt, 2021, Journal of Virology
Angiomotin-like 1 links paramyxovirus M proteins to NEDD4 family ubiquitin ligases
Greeshma Ray, Phuong Tieu Schmitt, Anthony P. Schmitt, 2019, Viruses
The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B
Jillian C. Carmichael, Hiroki Yokota, Rebecca C. Craven, Anthony Schmitt, John W. Wills, 2018, PLoS Pathogens
Mutations in the transmembrane domain and cytoplasmic tail of Hendra virus fusion protein disrupt viruslike- particle assembly
Nicolás Cifuentes-Muñoz, Weina Sun, Greeshma Ray, Phuong Tieu Schmitt, Stacy Webb, Kathleen Gibson, Rebecca Ellis Dutch, Anthony P. Schmitt, 2017, Journal of Virology
C-terminal DxD-containing sequences within paramyxovirus nucleocapsid proteins determine matrix protein compatibility and can direct foreign proteins into budding particles
Greeshma Ray, Phuong Tieu Schmitt, Anthony P. Schmitt, 2016, Journal of Virology on p. 3650-3660
Paramyxovirus glycoprotein incorporation, assembly and budding: A three way dance for infectious particle production
Farah El Najjar, Anthony P. Schmitt, Rebecca Ellis Dutch, 2014, Viruses on p. 3019-3054
Matrix proteins of Nipah and Hendra viruses interact with beta subunits of AP-3 complexes
Weina Sun, Thomas S. McCrory, Wei Young Khaw, Stephanie Petzing, Terrell Myers, Anthony P. Schmitt, 2014, Journal of Virology on p. 13099-13110
Point mutations in the paramyxovirus f protein that enhance fusion activity shift the mechanism of complement-mediated virus neutralization
John B. Johnson, Anthony P. Schmitt, Griffith D. Parks, 2013, Journal of Virology on p. 9250-9259
Most-Cited Papers
The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B
Jillian C. Carmichael, Hiroki Yokota, Rebecca C. Craven, Anthony Schmitt, John W. Wills, 2018, PLoS Pathogens
C-terminal DxD-containing sequences within paramyxovirus nucleocapsid proteins determine matrix protein compatibility and can direct foreign proteins into budding particles
Greeshma Ray, Phuong Tieu Schmitt, Anthony P. Schmitt, 2016, Journal of Virology on p. 3650-3660
Mutations in the transmembrane domain and cytoplasmic tail of Hendra virus fusion protein disrupt viruslike- particle assembly
Nicolás Cifuentes-Muñoz, Weina Sun, Greeshma Ray, Phuong Tieu Schmitt, Stacy Webb, Kathleen Gibson, Rebecca Ellis Dutch, Anthony P. Schmitt, 2017, Journal of Virology
Angiomotin-like 1 links paramyxovirus M proteins to NEDD4 family ubiquitin ligases
Greeshma Ray, Phuong Tieu Schmitt, Anthony P. Schmitt, 2019, Viruses
RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis
Lara Rheinemann, Diane Miller Downhour, Kate Bredbenner, Gaelle Mercenne, Kristen A. Davenport, Phuong Tieu Schmitt, Christina R. Necessary, John McCullough, Anthony P. Schmitt, Sanford M. Simon, Wesley I. Sundquist, Nels C. Elde, 2021, Cell on p. 5419-5431.e16
Paramyxovirus-like particles as protein delivery vehicles
Santosh Panthi, Phuong Tieu Schmitt, F. Jeffrey Lorenz, Brent A. Stanfield, Anthony P. Schmitt, 2021, Journal of Virology
Strain-Level Identification and Analysis of Avian Coronavirus Using Raman Spectroscopy and Interpretable Machine Learning
Peng Jin, Yin Ting Yeh, Jiarong Ye, Ziyang Wang, Yuan Xue, Na Zhang, Shengxi Huang, Elodie Ghedin, Huaguang Lu, A Schmitt, Anthony Schmitt, H Lu, Sharon Huang, M Terrones Maldonado, Mauricio Terrones, 2023,