Faculty

Anthony Schmitt

Professor of Molecular Immunology and Infectious Diseases
Huck Co-Hire with College of Agricultural Sciences

220 ASI Building
University Park, PA 16802

Email aps13@psu.edu
Phone 814-863-6781

Overview

The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.

Areas of Expertise

Paramyxoviridae Immunology and Microbiology
Paramyxovirus Keyphrases
Parainfluenza Virus 5 Immunology and Microbiology
Virus Immunology and Microbiology
M Protein Keyphrases
Virus-like Keyphrases
Virus-Like Particle Immunology and Microbiology
Virus Release Immunology and Microbiology

Strain-Level Identification and Analysis of Avian Coronavirus Using Raman Spectroscopy and Interpretable Machine Learning
Peng Jin, Yin Ting Yeh, Jiarong Ye, Ziyang Wang, Yuan Xue, Na Zhang, Shengxi Huang, Elodie Ghedin, Huaguang Lu, Anthony Schmitt, Sharon X. Huang, Mauricio Terrones, 2023, In: 2023 IEEE International Symposium on Biomedical Imaging, ISBI 2023
Date: 2023

RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis
Lara Rheinemann, Diane Miller Downhour, Kate Bredbenner, Gaelle Mercenne, Kristen A. Davenport, Phuong Tieu Schmitt, Christina R. Necessary, John McCullough, Anthony P. Schmitt, Sanford M. Simon, Wesley I. Sundquist, Nels C. Elde, Oct 14 2021, In: Cell
Date: Oct 14 2021

Paramyxovirus-like particles as protein delivery vehicles
Santosh Panthi, Phuong Tieu Schmitt, F. Jeffrey Lorenz, Brent A. Stanfield, Anthony P. Schmitt, Oct 2021, In: Journal of virology
Date: Oct 2021

Angiomotin-like 1 links paramyxovirus M proteins to NEDD4 family ubiquitin ligases
Greeshma Ray, Phuong Tieu Schmitt, Anthony P. Schmitt, Feb 2019, In: Viruses
Date: Feb 2019

The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B
Jillian C. Carmichael, Hiroki Yokota, Rebecca C. Craven, Anthony Schmitt, John W. Wills, May 2018, In: PLoS pathogens
Date: May 2018

Mutations in the transmembrane domain and cytoplasmic tail of Hendra virus fusion protein disrupt viruslike- particle assembly
Nicolás Cifuentes-Muñoz, Weina Sun, Greeshma Ray, Phuong Tieu Schmitt, Stacy Webb, Kathleen Gibson, Rebecca Ellis Dutch, Anthony P. Schmitt, Jul 1 2017, In: Journal of virology
Date: Jul 1 2017

C-terminal DxD-containing sequences within paramyxovirus nucleocapsid proteins determine matrix protein compatibility and can direct foreign proteins into budding particles
Greeshma Ray, Phuong Tieu Schmitt, Anthony P. Schmitt, 2016, In: Journal of virology
Date: 2016

Paramyxovirus glycoprotein incorporation, assembly and budding
Farah El Najjar, Anthony P. Schmitt, Rebecca Ellis Dutch, Aug 7 2014, In: Viruses
Date: Aug 7 2014

Matrix proteins of Nipah and Hendra viruses interact with beta subunits of AP-3 complexes
Weina Sun, Thomas S. McCrory, Wei Young Khaw, Stephanie Petzing, Terrell Myers, Anthony P. Schmitt, 2014, In: Journal of virology
Date: 2014

Point mutations in the paramyxovirus f protein that enhance fusion activity shift the mechanism of complement-mediated virus neutralization
John B. Johnson, Anthony P. Schmitt, Griffith D. Parks, Aug 2013, In: Journal of virology
Date: Aug 2013

View All Publications →

Msn2p, a zinc finger DNA-binding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae
Anthony P. Schmitt, Kevin Mcentee, Jun 11 1996, In: Proceedings of the National Academy of Sciences of the United States of America
Citations: 413

Paramyxovirus assembly and budding
Megan S. Harrison, Takemasa Sakaguchi, Anthony P. Schmitt, Sep 2010, In: International Journal of Biochemistry and Cell Biology
Citations: 164

Evidence for a new viral late-domain core sequence, FPIV, necessary for budding of a paramyxovirus
Anthony P. Schmitt, George P. Leser, Eiji Morita, Wesley I. Sundquist, Robert A. Lamb, Mar 2005, In: Journal of virology
Citations: 144

Requirements for budding of paramyxovirus simian virus 5 virus-like particles
Anthony P. Schmitt, George P. Leser, David L. Waning, Robert A. Lamb, 2002, In: Journal of virology
Citations: 130

Escaping from the cell
A. P. Schmitt, R. A. Lamb, 2004, In: Current topics in microbiology and immunology
Citations: 111

Mumps virus matrix, fusion, and nucleocapsid proteins cooperate for efficient production of virus-like particles
Ming Li, Phuong Tieu Schmitt, Zhuo Li, Thomas S. McCrory, Biao He, Anthony P. Schmitt, Jul 2009, In: Journal of virology
Citations: 107

Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAP
T. Oka, A. P. Schmitt, M. Sudol, Jan 5 2012, In: Oncogene
Citations: 101

Paramyxovirus glycoprotein incorporation, assembly and budding
Farah El Najjar, Anthony P. Schmitt, Rebecca Ellis Dutch, Aug 7 2014, In: Viruses
Citations: 100

Influenza Virus Assembly and Budding at the Viral Budozone
Anthony P. Schmitt, Robert A. Lamb, 2005, In: Virus Structure and Assembly
Citations: 92

Transcriptional factor mutations reveal regulatory complexities of heat shock and newly identified stress genes in Saccharomyces cerevisiae
Janet M. Treger, Anthony P. Schmitt, John R. Simon, Kevin McEntee, Oct 9 1998, In: Journal of Biological Chemistry
Citations: 87

View All Publications →

Anthony Schmitt

Overview

Areas of Expertise

Legal Statements