Overview
The research in the Walker lab is focused on how hormone signals in the testis maintain male fertility. Specifically, we are interested in the molecular mechanisms by which hormones such as follicle-stimulating hormone and testosterone support the survival and development of germ cells as they mature into sperm. The lab is working towards identifying hormone targets in testis cells that are required to maintain fertility. The results of these studies will identify previously unknown causes of male infertility, deliver targets for male contraceptive drug development and provide alternatives for surgical neutering of companion animals.