Establishment of Patient-Derived Organoids for Pediatric Cancer Research
Muhammad Younis, Tarlan Arjmandi, Mohammad Haque, Katherine McClain, Thussenthan Walter-Angelo, Franklin Back, Divya Gandra, Abigail Moore, Chandrika Behura, Vladimir S. Spiegelman, Hong Gang Wang, Sinisa Dovat, Jeremy Hengst, Giselle Saulnier Sholler,
May 2026,
In: Cancers
Date: May 2026
Recent advancements in the application of artificial intelligence-based approaches for screening, diagnosis, prognosis and treatment of cervical cancer
Subba Rao V. Tulimilli, Medha Karnik, Sam Cockroft, Anjali Devi S. Bettadapura, Suma M. Nataraj, Habeeb Shaik Mohideen, Sinisa Dovat, Arati Sharma, Subba Rao V. Madhunapantula,
May 2026,
In: Oncology Reviews
Date: May 2026
An Overview of the Mechanisms of HPV-Induced Cervical Cancer
Medha Karnik, Subba Rao V. Tulimilli, Preethi G. Anantharaju, Anjali Devi S. Bettadapura, Suma M. Natraj, Habeeb S. Mohideen, Sinisa Dovat, Arati Sharma, Subba Rao V. Madhunapantula,
Jan 2026,
In: Cancers
Date: Jan 2026
CK2α Deletion in the Hematopoietic Compartment Shows a Mild Alteration in Terminally Differentiated Cells and the Expansion of Stem Cells
Rajesh Rajaiah, Muhammad Daniyal, Marudhu Pandiyan Shanmugam, Hannah Valensi, Koby Duke, Katherine Mercer, Morgann Klink, Matthew Lanza, Yasin Uzun, Suming Huang, Sinisa Dovat, Chandrika Gowda Behura,
Jul 2025,
In: Cells
Date: Jul 2025
Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia
Yali Ding, Bing He, Daniel Bogush, Joseph Schramm, Chingakham Singh, Katarina Dovat, Julia Randazzo, Diwakar Tukaramrao, Jeremy Hengst, Charyguly Annageldiyev, Avinash Kudva, Dhimant Desai, Arati Sharma, Vladimir S. Spiegelman, Suming Huang, Chi T. Viet, Glenn Dorsam, Giselle Saulnier Scholler, Jame...,
2025,
In: Leukemia
Date: 2025
Targeting WDR5/ATAD2 signaling by the CK2/IKAROS axis demonstrates therapeutic efficacy in T-ALL
Qi Han, Yan Gu, Huimin Xiang, Linyao Zhang, Yan Wang, Chan Yang, Jun Li, Chelsea Steiner, Rosa Lapalombella, Jennifer A. Woyach, Yiping Yang, Sinisa Dovat, Chunhua Song, Zheng Ge,
2025,
In: Blood
Date: 2025
New precision medicine weapons for targeted treatment of high-risk B-cell precursor acute lymphoblastic leukemia
Sinisa Dovat, Joseph Schramm,
Dec 2024,
In: Haematologica
Date: Dec 2024
Upregulation of nuclear protein Hemgn by transcriptional repressor Gfi1 through repressing PU.1 contributes to the anti-apoptotic activity of Gfi1
Binod G C, Laney Jia Hoyt, Sinisa Dovat, Fan Dong,
Nov 2024,
In: Journal of Biological Chemistry
Date: Nov 2024
From Deworming to Cancer Therapy
Upendarrao Golla, Satyam Patel, Nyah Shah, Stella Talamo, Riya Bhalodia, David Claxton, Sinisa Dovat, Arati Sharma,
Oct 2024,
In: Cancers
Date: Oct 2024
Duocarmycin SA Reduces Proliferation and Increases Apoptosis in Acute Myeloid Leukemia Cells In Vitro
William A. Chen, Terry G. Williams, Leena So, Natalie Drew, Jie Fang, Pedro Ochoa, Nhi Nguyen, Yasmeen Jawhar, Jide Otiji, Penelope J. Duerksen-Hughes, Mark E. Reeves, Carlos A. Casiano, Hongjian Jin, Sinisa Dovat, Jun Yang, Kristopher E. Boyle, Olivia L. Francis-Boyle,
Apr 2024,
In: International journal of molecular sciences
Date: Apr 2024
Subtype-specific 3D genome alteration in acute myeloid leukaemia
Jie Xu, Fan Song, Huijue Lyu, Mikoto Kobayashi, Baozhen Zhang, Ziyu Zhao, Ye Hou, Xiaotao Wang, Yu Luan, Bei Jia, Lena Stasiak, Josiah Hiu yuen Wong, Qixuan Wang, Qi Jin, Qiushi Jin, Yihao Fu, Hongbo Yang, Ross C. Hardison, Sinisa Dovat, Leonidas C. Platanias, Yarui Diao, Yue Yang, Tomoko Yamada, Aa...,
Nov 10 2022,
In: Nature
Citations: 149
RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1
Irina A. Elcheva, Tyler Wood, Kathryn Chiarolanzio, Bryan Chim, Madeline Wong, Vikash Singh, Chethana P. Gowda, Qingli Lu, Markus Hafner, Sinisa Dovat, Zhenqiu Liu, Stefan A. Muljo, Vladimir S. Spiegelman,
Jan 1 2019,
In: Leukemia
Citations: 122
A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains
Sinisa Dovat, Tapani Ronni, Dana Russell, Roger Ferrini, Bradley S. Cobb, Stephen T. Smale,
Dec 1 2002,
In: Genes and Development
Citations: 116
Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia
Chunhua Song, Chandrika Gowda, Xiaokang Pan, Yali Ding, Yongqing Tong, Bi Hua Tan, Haijun Wang, Sunil Muthusami, Zheng Ge, Mansi Sachdev, Shantu G. Amin, Dhimant Desai, Krishne Gowda, Raghavendra Gowda, Gavin P. Robertson, Hilde Schjerven, Markus Muschen, Kimberly J. Payne, Sinisa Dovat,
Oct 8 2015,
In: Blood
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IL-7 dependence in human B lymphopoiesis increases during progression of ontogeny from cord blood to bone marrow
Yasmin Khan Parrish, Ineavely Baez, Terry Ann Milford, Abigail Benitez, Nicholas Galloway, Jaqueline Willeman Rogerio, Eva Sahakian, Mercy Kagoda, Grace Huang, Qian Lin Hao, Yazmar Sevilla, Lora W. Barsky, Ewa Zielinska, Mary A. Price, Nathan R. Wall, Sinisa Dovat, Kimberly J. Payne,
Apr 1 2009,
In: Journal of Immunology
Citations: 84
Congenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the ikaros gene
Frederick D. Goldman, Zafer Gurel, Duha Al-Zubeidi, Ari J. Fried, Michael Icardi, Chunhua Song, Sinisa Dovat,
Apr 2012,
In: Pediatric Blood and Cancer
Citations: 83
Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1
Marcela Popescu, Zafer Gurel, Tapani Ronni, Chunhua Song, Ka Ying Hung, Kimberly J. Payne, Sinisa Dovat,
May 15 2009,
In: Journal of Biological Chemistry
Citations: 73
Depletion of the human ion channel TRPM2 in neuroblastoma demonstrates its key role in cell survival through modulation of mitochondrial reactive oxygen species and bioenergetics
Lei Bao, Shu Jen Chen, Kathleen Conrad, Kerry Keefer, Thomas Abraham, John P. Lee, Ju Fang Wang, Xue Qian Zhang, Iwona Hirschler-Laszkiewicz, Hong Gang Wang, Sinisa Dovat, Brian Gans, Muniswamy Madesh, Joseph Y. Cheung, Barbara A. Miller,
Nov 18 2016,
In: Journal of Biological Chemistry
Citations: 67
Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy
Shu jen Chen, Lei Bao, Kerry Keefer, Santhanam Shanmughapriya, Longgui Chen, John Lee, Ju Fang Wang, Xue Qian Zhang, Iwona Hirschler-Laszkiewicz, Salim Merali, Carmen Merali, Yuka Imamura, Sinisa Dovat, Muniswamy Madesh, Joseph Y. Cheung, Hong Gang Wang, Barbara A. Miller,
Apr 1 2020,
In: Cell Death and Disease
Citations: 66
WDR5 high expression and its effect on tumorigenesis in leukemia
Zheng Ge, Evelyn J. Song, Yuka Imamura Kawasawa, Jianyong Li, Sinisa Dovat, Chunhua Song,
2016,
In: Oncotarget
Citations: 64
