Faculty

Nelson Yee

Professor of Medicine

T3413 400 University Drive
Hershey, PA 17033

Email nyee@pennstatehealth.psu.edu
Phone 717-531-0003 ext 280677

Overview

Early detection and diagnosis of cancer; Clinical and translational studies of new cancer therapies

Areas of Expertise

Pancreatic Cancer Keyphrases
Pancreas Cancer Medicine and Dentistry
Pancreas Cancer Pharmacology, Toxicology and Pharmaceutical Science
Receptor Pharmacology, Toxicology and Pharmaceutical Science
Pancreatic Adenocarcinoma Keyphrases
Biological Marker Pharmacology, Toxicology and Pharmaceutical Science
Neoplasm Pharmacology, Toxicology and Pharmaceutical Science
Pancreas Adenocarcinoma Pharmacology, Toxicology and Pharmaceutical Science

Factors Associated with Stage at Diagnosis in Pancreatic Cancer
Elen Deng, Manvita Mareboina, Ilias Georgakopoulos-Soares, Nelson S. Yee, May 2026, In: Biomedicines
Date: May 2026

Towards Collaborative Fairness in Federated Learning Under Imbalanced Covariate Shift
Tianrun Yu, Jiaqi Wang, Haoyu Wang, Mingquan Lin, Han Liu, Nelson S. Yee, Fenglong Ma, Aug 3 2025, In: KDD 2025 - Proceedings of the 31st ACM SIGKDD Conference on Knowledge Discovery and Data Mining
Date: Aug 3 2025

Comprehensive Analysis of Granzymes and Perforin Family Genes in Multiple Cancers
Manvita Mareboina, Katrina Bakhl, Stephanie Agioti, Nelson S. Yee, Ilias Georgakopoulos-Soares, Apostolos Zaravinos, Feb 2025, In: Biomedicines
Date: Feb 2025

Editorial
Nicholas A. Young, Jenifer R. Prosperi, Aharon G. Freud, Nelson S. Yee, Emanuel F. Petricoin, 2025, In: Frontiers in immunology
Date: 2025

Accuracy of Contrast-Enhanced Ultrasound for Hepatocellular Carcinoma Post-Transcatheter Arterial Embolization
Kathryn L. McGillen, William Watkins Pryor, Nelson S. Yee, Junjia Zhu, Karen L. Krok, Peter N. Waybill, Dec 2024, In: Journal of Clinical Medicine
Date: Dec 2024

A review on cell-free RNA profiling
Manvita Mareboina, Elen Deng, Ioannis Mouratidis, Nelson S. Yee, Nelly Pitteloud, Ilias Georgakopoulos-Soares, Dionysios V. Chartoumpekis, Sep 2024, In: Molecular Metabolism
Date: Sep 2024

Complete response to chemotherapy in a 6-year survivor of metastatic pancreatic cancer
Cynthia E. Burke, Nina L. Eng, Nelson S. Yee, June S. Peng, Jul 22 2024, In: BMJ case reports
Date: Jul 22 2024

Utilizing nullomers in cell-free RNA for early cancer detection
Austin Montgomery, Georgios Christos Tsiatsianis, Ioannis Mouratidis, Candace S.Y. Chan, Maria Athanasiou, Anastasios D. Papanastasiou, Verena Kantere, Nikos Syrigos, Ioannis Vathiotis, Konstantinos Syrigos, Nelson S. Yee, Ilias Georgakopoulos-Soares, 2024, In: Cancer gene therapy
Date: 2024

Peptide absent sequences emerging in human cancers
Georgios Christos Tsiatsianis, Candace S.Y. Chan, Ioannis Mouratidis, Nikol Chantzi, Anna Maria Tsiatsiani, Nelson S. Yee, Apostolos Zaravinos, Verena Kantere, Ilias Georgakopoulos-Soares, Jan 2024, In: European Journal of Cancer
Date: Jan 2024

Nab-Paclitaxel and Gemcitabine as First-Line Treatment of Metastatic Ampullary Adenocarcinoma with a Novel R-Spondin2 RNA Fusion and NTRK3 Mutation
Maryknoll P. Linscott, Havell Markus, Mackenzie Sennett, Catherine Abendroth, Nelson S. Yee, Aug 2023, In: Biomedicines
Date: Aug 2023

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Locally advanced, unresectable pancreatic cancer
Edward P. Balaban, Pamela B. Mangu, Alok A. Khorana, Manish A. Shah, Somnath Mukherjee, Christopher H. Crane, Milind M. Javle, Jennifer R. Eads, Peter Allen, Andrew H. Ko, Anitra Engebretson, Joseph M. Herman, John H. Strickler, Al B. Benson, Susan Urba, Nelson S. Yee, Aug 1 2016, In: Journal of Clinical Oncology
Citations: 347

Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN)
J. L. Welsh, B. A. Wagner, T. J. Van'T Erve, P. S. Zehr, D. J. Berg, T. R. Halfdanarson, N. S. Yee, K. L. Bodeker, J. Du, L. J. Roberts, J. Drisko, M. Levine, G. R. Buettner, J. J. Cullen, Mar 2013, In: Cancer Chemotherapy and Pharmacology
Citations: 261

Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells
Hubert Serve, Nelson S. Yee, Gregory Stella, Laura Sepp-Lorenzino, Jimmy C. Tan, Peter Besmer, Feb 1 1995, In: EMBO Journal
Citations: 204

Role of kit-ligand in proliferation and suppression of apoptosis in mast cells
Nelson S. Yee, Inbok Paek, Peter Besmer, Jun 1 1994, In: Journal of Experimental Medicine
Citations: 151

Mechanism of down-regulation of c-kit receptor
N. S. Yee, C. W.M. Hsiau, H. Serve, K. Vosseller, P. Besmer, Dec 16 1994, In: Journal of Biological Chemistry
Citations: 141

Exocrine pancreas development in zebrafish
Nelson S. Yee, Kristin Lorent, Michael Pack, Aug 1 2005, In: Developmental biology
Citations: 116

Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells
N. S. Yee, H. Langen, P. Besmer, Jul 5 1993, In: Journal of Biological Chemistry
Citations: 116

Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma
Nelson S. Yee, Weiqiang Zhou, Minsun Lee, Nov 2010, In: Cancer Letters
Citations: 95

c-kit receptor signaling through its phosphatidylinositide-3'-kinase- binding site and protein kinase C
Keith Vosseller, Gregory Stella, Nelson S. Yee, Peter Besmer, May 1997, In: Molecular Biology of the Cell
Citations: 95

Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg<sup>2+</sup>-sensitive Socs3a signaling in development and cancer
Nelson S. Yee, Weiqiang Zhou, I. Chau Liang, Mar 2011, In: DMM Disease Models and Mechanisms
Citations: 93

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Centers & Institutes

Center for Biodevices

Elsevier Pure Profile

Nelson Yee

Overview

Areas of Expertise

Legal Statements