Lu Bai

Hi-C calibration by chemically induced chromosomal interactions
Yi Li, Christoph W.A. Fischer, Fan Zou, Manyu Du, Lu Bai, 2026, In: EMBO Reports
Date: 2026

Native nucleosome-positioning elements as alternatives to the 601 sequence for nucleosome repositioning studies
Ruo Wen Chen, Shane D. Stoeber, Ilana M. Nodelman, Hengye Chen, Wenxuan Yang, Gregory D. Bowman, Lu Bai, Michael G. Poirier, Sep 23 2025, In: Nucleic acids research
Date: Sep 23 2025

DNA methylation-based high-resolution mapping of long-distance chromosomal interactions in nucleosome-depleted regions
Yi Li, James Lee, Lu Bai, Dec 2024, In: Nature communications
Date: Dec 2024

Systematic dissection of sequence features affecting binding specificity of a pioneer factor reveals binding synergy between FOXA1 and AP-1
Cheng Xu, Holly Kleinschmidt, Jianyu Yang, Erik M. Leith, Jenna Johnson, Song Tan, Shaun Mahony, Lu Bai, Aug 8 2024, In: Molecular cell
Date: Aug 8 2024

Pioneer factors
Shane Stoeber, Holly Godin, Cheng Xu, Lu Bai, 2024, In: Critical Reviews in Biochemistry and Molecular Biology
Date: 2024

Investigating pioneer factor activity and its coordination with chromatin remodelers using integrated synthetic oligo assay
Hengye Chen, Chao Yan, Archana Dhasarathy, Michael Kladde, Lu Bai, Jun 16 2023, In: STAR Protocols
Date: Jun 16 2023

Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions
Benjamin T. Donovan, Hengye Chen, Priit Eek, Zhiyuan Meng, Caroline Jipa, Song Tan, Lu Bai, Michael G. Poirier, Apr 20 2023, In: Molecular cell
Date: Apr 20 2023

Predicting nucleosome positioning using statistical equilibrium models in budding yeast
Hungyo Kharerin, Lu Bai, Mar 17 2023, In: STAR Protocols
Date: Mar 17 2023

Using Synthetic DNA Libraries to Investigate Chromatin and Gene Regulation
Holly Kleinschmidt, Cheng Xu, Lu Bai, 2023, In: Chromosoma
Date: 2023

Chemically Induced Chromosomal Interaction (CICI) method to study chromosome dynamics and its biological roles
Manyu Du, Fan Zou, Yi Li, Yujie Yan, Lu Bai, Dec 2022, In: Nature communications
Date: Dec 2022

High-resolution dynamic mapping of histone-DNA interactions in a nucleosome
Michael A. Hall, Alla Shundrovsky, Lu Bai, Robert M. Fulbright, John T. Lis, Michelle D. Wang, Feb 2009, In: Nature Structural and Molecular Biology
Citations: 339

Transcription under torsion
Jie Ma, Lu Bai, Michelle D. Wang, 2013, In: Science
Citations: 278

Single-Molecule Studies Reveal Dynamics of DNA Unwinding by the Ring-Shaped T7 Helicase
Daniel S. Johnson, Lu Bai, Benjamin Y. Smith, Smita S. Patel, Michelle D. Wang, Jun 29 2007, In: Cell
Citations: 216

Gene regulation by nucleosome positioning
Lu Bai, Alexandre V. Morozov, Nov 2010, In: Trends in Genetics
Citations: 201

Modulation of Fluorescent Protein Chromophores to Detect Protein Aggregation with Turn-On Fluorescence
Yu Liu, Charles H. Wolstenholme, Gregory C. Carter, Hongbin Liu, Hang Hu, Leeann S. Grainger, Kun Miao, Matthew Fares, Conner A. Hoelzel, Hemant P. Yennawar, Gang Ning, Manyu Du, Lu Bai, Xiaosong Li, Xin Zhang, Jun 20 2018, In: Journal of the American Chemical Society
Citations: 195

Sequence-dependent kinetic model for transcription elongation by RNA polymerase
Lu Bai, Alla Shundrovsky, Michelle D. Wang, Nov 19 2004, In: Journal of Molecular Biology
Citations: 132

Single-molecule analysis of RNA polymerase transcription
Lu Bai, Thomas J. Santangelo, Michelle D. Wang, 2006, In: Annual Review of Biophysics and Biomolecular Structure
Citations: 114

Synergistic action of RNA polymerases in overcoming the nucleosomal barrier
Jing Jin, Lu Bai, Daniel S. Johnson, Robert M. Fulbright, Maria L. Kireeva, Mikhail Kashlev, Michelle D. Wang, Jun 2010, In: Nature Structural and Molecular Biology
Citations: 109

Kinetic competition between elongation rate and binding of NELF controls promoter-proximal pausing
Jian Li, Yingyun Liu, Ho Sung Rhee, Saikat Kumar B. Ghosh, Lu Bai, B. Franklin Pugh, David S. Gilmour, Jun 6 2013, In: Molecular cell
Citations: 98

Multiple Sequence-Specific Factors Generate the Nucleosome-Depleted Region on CLN2 Promoter
Lu Bai, Andrej Ondracka, Frederick R. Cross, May 20 2011, In: Molecular cell
Citations: 89

Centers & Institutes

• Center for Cellular Dynamics

• Bioinformatics and Genomics IGDP
• Molecular, Cellular, and Integrative Biosciences IGDP

• Neha Patwardhan

• Elsevier Pure Profile