J. Martin Bollinger

A ferritin-like diiron oxygenase BioE initiates bacterial biotin synthesis, a promising antivirulence target
Yongchang Xu, Meng Zhang, Yingying Fu, Xiaoqiang Yang, Man Huang, Qiuying Qin, Yanhua Kang, Xinyu Su, Jiaming Fang, J. Martin Bollinger, Zhi Ruan, Youjun Feng, Dec 9 2025, In: Proceedings of the National Academy of Sciences of the United States of America
Date: Dec 9 2025

Experimental Evidence for Radical-Polar Crossover in Competition with, Rather Than Preceding, Alkene Formation by Microbial Ethylene-Forming Enzyme
Evan J. Burke, Chao Wang, Holly Lussier, Elvira R. Sayfutyarova, Alexey Silakov, Carsten Krebs, J. Martin Bollinger, Jeffrey W. Slater, Dec 3 2025, In: Journal of the American Chemical Society
Date: Dec 3 2025

Iron-sulfur clusters in SARS-CoV-2 exoribonuclease and methyltransferase complexes
Nunziata Maio, Umberto Terranova, Yan Li, J. Martin Bollinger, Carsten Krebs, Tracey A. Rouault, Dec 2025, In: Nature communications
Date: Dec 2025

Hydralazine inhibits cysteamine dioxygenase to treat preeclampsia and senesce glioblastoma
Kyosuke Shishikura, Jiasong Li, Yiming Chen, Nate R. McKnight, Thomas P. Keeley, Katelyn A. Bustin, Eric W. Barr, Snehil R. Chilkamari, Mahaa Ayub, Sun Woo Kim, Zongtao Lin, Ren Ming Hu, Kelly Hicks, Xie Wang, Donald M. O’Rourke, J. Martin Bollinger, Zev A. Binder, William H. Parsons, Kirill A. Ma..., Oct 15 2025, In: Science Advances
Date: Oct 15 2025

A Structurally Divergent Class Ia Ribonucleotide Reductase from a Tick-Borne Pathogen
Olivia M. Peduzzi, Gavin M. Palowitch, John P. Gajewski, Kai Hu, Alyssa Wheeler, Tatiana N. Laremore, Steve Silletti, Elizabeth A. Komives, Benjamin D. Allen, Alexey Silakov, Carsten Krebs, J. Martin Bollinger, Chi Yun Lin, Amie K. Boal, Sep 16 2025, In: Biochemistry
Date: Sep 16 2025

Heme Oxygenase–Like Metalloenzymes
Sarah R. Pope, Molly J. McBride, Mrutyunjay A. Nair, Xavier E. Salas-Solá, Carsten Krebs, J. Martin Bollinger, Amie K. Boal, Jun 20 2025, In: Annual review of biochemistry
Date: Jun 20 2025

Structural Elucidation of the Reduced Mn(III)/Fe(III) Intermediate of the Radical-Initiating Metallocofactor in Chlamydia trachomatis Ribonucleotide Reductase
Ryan J. Martinie, Jovan Livada, Nyaari Kothiya, J. Martin Bollinger, Carsten Krebs, Alexey Silakov, Mar 4 2025, In: Biochemistry
Date: Mar 4 2025

Azetidine amino acid biosynthesis by non-haem iron-dependent enzymes
Yanan Du, Anyarat Thanapipatsiri, Jesús J. Blancas Cortez, Xavier E. Salas-Solá, Chi Yun Lin, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, Kenichi Yokoyama, 2025, In: Nature Chemistry
Date: 2025

Biochemical Studies of a Cyanobacterial Halogenase Support the Involvement of a Dimetal Cofactor
Michelle L. Wang, Nathaniel R. Glasser, Mrutyunjay A. Nair, Carsten Krebs, J. Martin Bollinger, Emily P. Balskus, 2025, In: Biochemistry
Date: 2025

Dynamic metal coordination controls chemoselectivity in a radical halogenase
Elijah N. Kissman, Ioannis Kipouros, Jeffrey W. Slater, Elizabeth A. Stone, Avery Y. Yang, Augustin Braun, Alder R. Ensberg, Andrew M. Whitten, Kuntal Chatterjee, Isabel Bogacz, Junko Yano, J. Martin Bollinger, Michelle C.Y. Chang, 2025, In: Nature Chemical Biology
Date: 2025

Non-heme Fe(IV)-oxo intermediates
Carsten Krebs, Danica Galonić Fujimori, Christopher T. Walsh, J. Martin Bollinger, Jul 2007, In: Accounts of Chemical Research
Citations: 904

The first direct characterization of a high-valent iron intermediate in the reaction of an α-ketoglutarate-dependent dioxygenase
John C. Price, Eric W. Barr, Bhramara Tirupati, J. Martin Bollinger, Carsten Krebs, Jun 24 2003, In: Biochemistry
Citations: 676

Evidence for Hydrogen Abstraction from C1 of Taurine by the High-Spin Fe(IV) Intermediate Detected during Oxygen Activation by Taurine:α -Ketoglutarate Dioxygenase (TauD)
John C. Price, Eric W. Barr, Timothy E. Glass, Carsten Krebs, J. Martin Bollinger, Oct 29 2003, In: Journal of the American Chemical Society
Citations: 384

Mechanism of assembly of the tyrosyl radical-dinuclear iron cluster cofactor of ribonucleotide reductase
J. M. Bollinger, D. E. Edmondson, B. H. Huynh, J. Filley, J. R. Norton, J. Stubbe, 1991, In: Science
Citations: 364

Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3
Danica P. Galonić, Eric W. Barr, Christopher T. Walsh, J. Martin Bollinger, Carsten Krebs, Feb 2007, In: Nature Chemical Biology
Citations: 317

EXAFS spectroscopic evidence for an Fe=O unit in the Fe(IV) intermediate observed during oxygen activation by taurine:α-ketoglutarate dioxygenase
Pamela J. Riggs-Gelasco, John C. Price, Robert B. Guyer, Jessica H. Brehm, Eric W. Barr, J. Martin Bollinger, Carsten Krebs, Jul 7 2004, In: Journal of the American Chemical Society
Citations: 298

Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase
Lee M. Hoffart, Eric W. Barr, Robert B. Guyer, J. Martin Bollinger, Carsten Krebs, Oct 3 2006, In: Proceedings of the National Academy of Sciences of the United States of America
Citations: 296

2′-Deoxy-2′-methylenecytidine and 2′-Deoxy-2′,2′-difluorocytidine 5′-Diphosphates
C. H. Baker, J. Banzon, J. M. Bollinger, J. Stubbe, V. Samano, M. J. Robins, B. Lippert, E. Jarvi, R. Resvick, Jun 1 1991, In: Journal of Medicinal Chemistry
Citations: 251

Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2
Megan L. Matthews, Christopher S. Neumann, Linde A. Miles, Tyler L. Grove, Squire J. Booker, Carsten Krebs, Christopher T. Walsh, J. Martin Bollinger, Oct 20 2009, In: Proceedings of the National Academy of Sciences of the United States of America
Citations: 229

Elucidation of the Fe(iv)=O intermediate in the catalytic cycle of the halogenase SyrB2
Shaun D. Wong, Martin Srnec, Megan L. Matthews, Lei V. Liu, Yeonju Kwak, Kiyoung Park, Caleb B. Bell, E. Ercan Alp, Jiyong Zhao, Yoshitaka Yoda, Shinji Kitao, Makoto Seto, Carsten Krebs, J. Martin Bollinger, Edward I. Solomon, 2013, In: Nature
Citations: 219

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