Glucuronidation metabolomic fingerprinting to map host-microbe metabolism
Nina R. Boyle, Josh J. Sekela, Mingxun Wang, Helena Mannochio-Russo, Jeong Joo Pyo, Min Soo Kim, Shuchang Tian, Imhoi Koo, Elliot S. Friedman, Ceylan Tanes, Mallappa Anitha, Yuan Tian, Ethan W. Morgan, Iain A. Murray, Joseph P. Zackular, Kyle Bittinger, James D. Lewis, Gary H. Perdew, Gary D. Wu, Ba...,
Dec 2026,
In: Nature communications
Date: Dec 2026
Systemic rhythmicity of host and bacterial bile acid amidates in the mouse
Erin R. Reilly, Vincent Charron-Lamoureux, Helena Mannochio-Russo, Ethan W. Morgan, Nina R. Boyle, Imhoi Koo, Emma Coudriet, Fuhua Hao, Ipsita Mohanty, Gary H. Perdew, Pieter C. Dorrestein, Andrew D. Patterson,
Apr 15 2026,
In: Cell Systems
Date: Apr 15 2026
BRD4-mediated ER membrane contact creates functionally distinct mitochondrial subtypes
Brandon Chen, Drew C. Stark, Pankaj V. Jadhav, Theophilus M. Lynn-Nguyen, Benjamin S. Halligan, Nicholas J. Rossiter, Nicole Sindoni, Myungsun Shin, Joao A. Paulo, Matthew Chang, Imhoi Koo, Sergei Koshkin, Sanjana Eyunni, Paolo Ronchi, Michelle T. Paulsen, Harrison S. Greenbaum, Mariana T. Ruckert, ...,
Mar 5 2026,
In: Molecular cell
Date: Mar 5 2026
Long-chain fatty acid utilization in Eisenmenger syndrome
Omer Cavus, Manisha J. Oza, Austin Angelotti, Jennifer DeSalvo, Imhoi Koo, Victor Ruiz-Velasco, Elisa A. Bradley,
Jan 1 2026,
In: Progress in Pediatric cardiology
Date: Jan 1 2026
High-fat diet-induced obesity alters the dose-dependent metabolism of (–)-epigallocatechin-3-gallate in mice
Soomee Hwang, Imhoi Koo, Andrew D. Patterson, Joshua D. Lambert,
Nov 2025,
In: Nutrition Research
Date: Nov 2025
Fibroblast lipid metabolism through ACSL4 regulates epithelial sensitivity to ferroptosis in IBD
Wesley Huang, Yuezhong Zhang, Nupur K. Das, Sumeet Solanki, Chesta Jain, Marwa O. El-Derany, Imhoi Koo, Hannah N. Bell, Noora Aabed, Rashi Singhal, Cristina Castillo, Kathryn Buscher, Yinzhi Ying, James Dimitroff, Ankit Sharma, Jiaqi Shi, Simon P. Hogan, Michael K. Dame, Peter D.R. Higgins, Justin A...,
Jul 2025,
In: Nature Metabolism
Date: Jul 2025
Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma
Nneka E. Mbah, Amy L. Myers, Peter Sajjakulnukit, Chan Chung, Joyce K. Thompson, Hanna S. Hong, Heather Giza, Derek Dang, Zeribe C. Nwosu, Mengrou Shan, Stefan R. Sweha, Daniella D. Maydan, Brandon Chen, Li Zhang, Brian Magnuson, Zirui Zhu, Megan Radyk, Brooke Lavoie, Viveka Nand Yadav, Imhoi Koo, A...,
Dec 2024,
In: Nature communications
Date: Dec 2024
Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation
Shigetoshi Yokoyama, Imhoi Koo, Daisuke Aibara, Yuan Tian, Iain A. Murray, Stephanie L. Collins, Denise M. Coslo, Mari Kono, Jeffrey M. Peters, Richard L. Proia, Frank J. Gonzalez, Gary H. Perdew, Andrew D. Patterson,
Oct 28 2024,
In: Advanced Science
Date: Oct 28 2024
Inhibition of heme-thiolate monooxygenase CYP1B1 prevents hepatic stellate cell activation and liver fibrosis by accumulating trehalose
Hung Chun Tung, Jong Won Kim, Junjie Zhu, Sihan Li, Jiong Yan, Qing Liu, Imhoi Koo, Sergei A. Koshkin, Fuhua Hao, Guo Zhong, Meishu Xu, Zehua Wang, Jingyuan Wang, Yixian Huang, Yue Xi, Xinran Cai, Pengfei Xu, Songrong Ren, Takanobu Higashiyama, Frank J. Gonzalez, Song Li, Nina Isoherranen, Da Yang, ...,
Sep 25 2024,
In: Science Translational Medicine
Date: Sep 25 2024
Modulation of Ceramide-Induced Apoptosis in Enteric Neurons by Aryl Hydrocarbon Receptor Signaling
Mallappa Anitha, Supriya M. Kumar, Imhoi Koo, Gary H. Perdew, Shanthi Srinivasan, Andrew D. Patterson,
Aug 2024,
In: International journal of molecular sciences
Date: Aug 2024
The microbiome modulating activity of bile acids
Yuan Tian, Wei Gui, Imhoi Koo, Philip B. Smith, Erik L. Allman, Robert G. Nichols, Bipin Rimal, Jingwei Cai, Qing Liu, Andrew D. Patterson,
2020,
In: Gut microbes
Citations: 237
Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity
Fangcong Dong, Fuhua Hao, Iain A. Murray, Philip B. Smith, Imhoi Koo, Alyssa M. Tindall, Penny M. Kris-Etherton, Krishne Gowda, Shantu G. Amin, Andrew D. Patterson, Gary H. Perdew,
Nov 9 2020,
In: Gut microbes
Citations: 230
Bile salt hydrolase catalyses formation of amine-conjugated bile acids
Bipin Rimal, Stephanie L. Collins, Ceylan E. Tanes, Edson R. Rocha, Megan A. Granda, Sumeet Solanki, Nushrat J. Hoque, Emily C. Gentry, Imhoi Koo, Erin R. Reilly, Fuhua Hao, Devendra Paudel, Vishal Singh, Tingting Yan, Min Soo Kim, Kyle Bittinger, Joseph P. Zackular, Kristopher W. Krausz, Dhimant De...,
Feb 22 2024,
In: Nature
Citations: 190
The underappreciated diversity of bile acid modifications
Ipsita Mohanty, Helena Mannochio-Russo, Joshua V. Schweer, Yasin El Abiead, Wout Bittremieux, Shipei Xing, Robin Schmid, Simone Zuffa, Felipe Vasquez, Valentina B. Muti, Jasmine Zemlin, Omar E. Tovar-Herrera, Sarah Moraïs, Dhimant Desai, Shantu Amin, Imhoi Koo, Christoph W. Turck, Itzhak Mizrahi, P...,
Mar 28 2024,
In: Cell
Citations: 162
The Pretreatment Gut Microbiome Is Associated With Lack of Response to Methotrexate in New-Onset Rheumatoid Arthritis
Alejandro Artacho, Sandrine Isaac, Renuka Nayak, Alejandra Flor-Duro, Margaret Alexander, Imhoi Koo, Julia Manasson, Philip B. Smith, Pamela Rosenthal, Yamen Homsi, Percio Gulko, Javier Pons, Leonor Puchades-Carrasco, Peter Izmirly, Andrew Patterson, Steven B. Abramson, Antonio Pineda-Lucena, Peter ...,
2020,
In: Arthritis and Rheumatology
Citations: 132
Berberine directly affects the gut microbiota to promote intestinal farnesoid X receptor activation
Yuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha, Andrew D. Patterson,
Feb 2019,
In: Drug Metabolism and Disposition
Citations: 113
Comparative analysis of mass spectral matching-based compound identification in gas chromatography-mass spectrometry
Imhoi Koo, Seongho Kim, Xiang Zhang,
Jul 12 2013,
In: Journal of Chromatography A
Citations: 94
Wavelet- and fourier-transform-based spectrum similarity approaches to compound identification in gas chromatography/mass spectrometry
Imhoi Koo, Xiang Zhang, Seongho Kim,
Jul 15 2011,
In: Analytical Chemistry
Citations: 82
Current Challenges and Recent Developments in Mass Spectrometry-Based Metabolomics
Stephanie L. Collins, Imhoi Koo, Jeffrey M. Peters, Philip B. Smith, Andrew D. Patterson,
2021,
In: Annual Review of Analytical Chemistry
Citations: 80
Compound identification in GC-MS by simultaneously evaluating the mass spectrum and retention index
Xiaoli Wei, Imhoi Koo, Seongho Kim, Xiang Zhang,
Apr 15 2014,
In: Analyst
Citations: 77
