David Boehr

Solution-state nuclear magnetic resonance studies of the Salmonella typhimurium tryptophan synthase complex
Rebecca N. D'Amico, Somnath Mondal, Dennis S. Winston, David D. Boehr, Jun 2026, In: Biochemistry and Biophysics Reports
Date: Jun 2026

Structure, Function and Inhibition of Helicases Involved in Virus Infection
Gisoo Sarvari, David D. Boehr, Feb 2026, In: Biomolecules
Date: Feb 2026

Multivalent Interactions Between the Picornavirus 3C(D) Main Protease and RNA Oligonucleotides Induce Liquid–Liquid Phase Separation
Somnath Mondal, Saumyak Mukherjee, Kevin E.W. Namitz, Neela H. Yennawar, David D. Boehr, Nov 2025, In: Viruses
Date: Nov 2025

Molecular determinants of picornavirus 3C protease binding to phosphoinositide-enriched lipid membranes
Jie Yu, Dennis S. Winston, David D. Boehr, Sep 2025, In: Journal of Biological Chemistry
Date: Sep 2025

Multi-Enzyme Synergy and Allosteric Regulation in the Shikimate Pathway
Sara Khan, David D. Boehr, Aug 2025, In: Catalysts
Date: Aug 2025

Editorial
David D. Boehr, 2024, In: Frontiers in Molecular Biosciences
Date: 2024

Picornavirus 3C Proteins Intervene in Host Cell Processes through Proteolysis and Interactions with RNA
Somnath Mondal, Gisoo Sarvari, David D. Boehr, Dec 2023, In: Viruses
Date: Dec 2023

Allostery, engineering and inhibition of tryptophan synthase
Rebecca N. D'Amico, David D. Boehr, Oct 2023, In: Current Opinion in Structural Biology
Date: Oct 2023

Regulatory mechanisms triggered by enzyme interactions with lipid membrane surfaces
Jie Yu, David D. Boehr, 2023, In: Frontiers in Molecular Biosciences
Date: 2023

Special Issue “10th Anniversary of Catalysts
Evangelos Topakas, David Boehr, Roland Wohlgemuth, Dec 2022, In: Catalysts
Date: Dec 2022

The role of dynamic conformational ensembles in biomolecular recognition
David D. Boehr, Ruth Nussinov, Peter E. Wright, Nov 2009, In: Nature Chemical Biology
Citations: 1,731

The dynamic energy landscape of dihydrofolate reductase catalysis
David D. Boehr, Dan McElheny, H. Jane Dyson, Peter E. Wrightt, Sep 15 2006, In: Science
Citations: 856

An NMR perspective on enzyme dynamics
David D. Boehr, H. Jane Dyson, Peter E. Wright, Aug 2006, In: Chemical Reviews
Citations: 428

How do proteins interact?
David D. Boehr, Peter E. Wright, Jun 13 2008, In: Science
Citations: 177

Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymes [11]
Steven J. Sucheck, Andrew L. Wong, Kathryn M. Koeller, David D. Boehr, Kari Ann Draker, Pamela Sears, Gerard D. Wright, Chi Huey Wong, May 31 2000, In: Journal of the American Chemical Society
Citations: 141

Millisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands
David D. Boehr, Dan McElheny, H. Jane Dyson, Peter E. Wright, Jan 26 2010, In: Proceedings of the National Academy of Sciences of the United States of America
Citations: 125

Analysis of the π-π stacking interactions between the aminoglycoside antibiotic kinase APH(3′)-IIIa and its nucleotide ligands
David D. Boehr, Adam R. Farley, Gerard D. Wright, James R. Cox, Nov 1 2002, In: Chemistry and Biology
Citations: 92

Broad-spectrum peptide inhibitors of aminoglycoside antibiotic resistance enzymes
David D. Boehr, Kari Ann Draker, Kalinka Koteva, Manjeet Bains, Robert E. Hancock, Gerard D. Wright, Feb 1 2003, In: Chemistry and Biology
Citations: 90

Motif D of viral RNA-dependent RNA polymerases determines efficiency and fidelity of nucleotide addition
Xiaorong Yang, Eric D. Smidansky, Kenneth R. Maksimchuk, David Lum, Jesse L. Welch, Jamie J. Arnold, Craig E. Cameron, David D. Boehr, Sep 5 2012, In: Structure
Citations: 85

A distal mutation perturbs dynamic amino acid networks in dihydrofolate reductase
David D. Boehr, Jason R. Schnell, Dan McElheny, Sung Hun Bae, Brendan M. Duggan, Stephen J. Benkovic, H. Jane Dyson, Peter E. Wright, Jul 9 2013, In: Biochemistry
Citations: 75

Centers & Institutes

• Center for Structural Biology

• Elsevier Pure Profile