Christopher Chen

Cerebellar Time and Relative Time
Andras Hajnal, Kate Levenberg, Peter Adam, Christopher H. Chen, Jun 2026, In: Cerebellum
Date: Jun 2026

A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain
Christopher H. Chen, Leannah N. Newman, Amanda P. Stark, Katherine E. Bond, Dawei Zhang, Stefano Nardone, Charles R. Vanderburg, Naeem M. Nadaf, Zhiyi Yao, Kefiloe Mutume, Isabella Flaquer, Bradford B. Lowell, Evan Z. Macosko, Wade G. Regehr, Nov 2023, In: Nature Neuroscience
Date: Nov 2023

Cerebellar granule cell signaling is indispensable for normal motor performance
Joon Hyuk Lee, Mehak M. Khan, Amanda P. Stark, Soobin Seo, Aliya Norton, Zhiyi Yao, Christopher H. Chen, Wade G. Regehr, May 30 2023, In: Cell Reports
Date: May 30 2023

Unusually Slow Spike Frequency Adaptation in Deep Cerebellar Nuclei Neurons Preserves Linear Transformations on the Subsecond Timescale
Mehak M. Khan, Shuting Wu, Christopher H. Chen, Wade G. Regehr, Oct 5 2022, In: Journal of Neuroscience
Date: Oct 5 2022

Mechanism of stress-induced attacks in an episodic neurologic disorder
Heather D. Snell, Ariel Vitenzon, Esra Tara, Chris Chen, Jaafar Tindi, Bryen A. Jordan, Kamran Khodakhah, Apr 2022, In: Science Advances
Date: Apr 2022

Climbing fiber synapses rapidly and transiently inhibit neighboring Purkinje cells via ephaptic coupling
Kyung Seok Han, Christopher H. Chen, Mehak M. Khan, Chong Guo, Wade G. Regehr, Nov 1 2020, In: Nature Neuroscience
Date: Nov 1 2020

Title
Skyler L. Jackman, Christopher H. Chen, Heather L. Offermann, Iain R. Drew, Bailey M. Harrison, Anna M. Bowman, Katelyn M. Flick, Isabella Flaquer, Wade G. Regehr, Apr 2020, In: eLife
Date: Apr 2020

In Vivo Targeted Expression of Optogenetic Proteins Using Silk/AAV Films
Skyler L. Jackman, Christopher H. Chen, Wade G. Regehr, Feb 2019, In: Journal of Visualized Experiments
Date: Feb 2019

Cerebellar modulation of the reward circuitry and social behavior
Ilaria Carta, Christopher H. Chen, Amanda L. Schott, Schnaude Dorizan, Kamran Khodakhah, Jan 18 2019, In: Science
Date: Jan 18 2019

Ephaptic Coupling Promotes Synchronous Firing of Cerebellar Purkinje Cells
Kyung Seok Han, Chong Guo, Christopher H. Chen, Laurens Witter, Tomas Osorno, Wade G. Regehr, Nov 7 2018, In: Neuron
Date: Nov 7 2018

Cerebellar modulation of the reward circuitry and social behavior
Ilaria Carta, Christopher H. Chen, Amanda L. Schott, Schnaude Dorizan, Kamran Khodakhah, Jan 18 2019, In: Science
Citations: 475

Short latency cerebellar modulation of the basal ganglia
Christopher H. Chen, Rachel Fremont, Eduardo E. Arteaga-Bracho, Kamran Khodakhah, Jan 1 2014, In: Nature Neuroscience
Citations: 241

Acute administration of non-classical estrogen receptor agonists attenuates ischemia-induced hippocampal neuron loss in middle-aged female rats
Diane Lebesgue, Michael Traub, Maxine De Butte-Smith, Christopher Chen, R. Suzanne Zukin, Martin J. Kelly, Anne M. Etgen, Jan 8 2010, In: PloS one
Citations: 131

Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease
Aldrin E. Molero, Eduardo E. Arteaga-Bracho, Christopher H. Chen, Maria Gulinello, Michael L. Winchester, Nandini Pichamoorthy, Solen Gokhan, Kamran Khodakhah, Mark F. Mehler, May 17 2016, In: Proceedings of the National Academy of Sciences of the United States of America
Citations: 109

Ephaptic Coupling Promotes Synchronous Firing of Cerebellar Purkinje Cells
Kyung Seok Han, Chong Guo, Christopher H. Chen, Laurens Witter, Tomas Osorno, Wade G. Regehr, Nov 7 2018, In: Neuron
Citations: 96

Intracerebroventricular administration of TNF-like weak inducer of apoptosis induces depression-like behavior and cognitive dysfunction in non-autoimmune mice
Jing Wen, Christopher Holden Chen, Ariel Stock, Jessica Doerner, Maria Gulinello, Chaim Putterman, May 1 2016, In: Brain, Behavior, and Immunity
Citations: 63

Title
Skyler L. Jackman, Christopher H. Chen, Heather L. Offermann, Iain R. Drew, Bailey M. Harrison, Anna M. Bowman, Katelyn M. Flick, Isabella Flaquer, Wade G. Regehr, Apr 2020, In: eLife
Citations: 45

Silk Fibroin Films Facilitate Single-Step Targeted Expression of Optogenetic Proteins
Skyler L. Jackman, Christopher H. Chen, Selmaan N. Chettih, Shay Q. Neufeld, Iain R. Drew, Chimuanya K. Agba, Isabella Flaquer, Alexis N. Stefano, Thomas J. Kennedy, Justine E. Belinsky, Keiramarie Roberston, Celia C. Beron, Bernardo L. Sabatini, Christopher D. Harvey, Wade G. Regehr, Mar 20 2018, In: Cell Reports
Citations: 39

Climbing fiber synapses rapidly and transiently inhibit neighboring Purkinje cells via ephaptic coupling
Kyung Seok Han, Christopher H. Chen, Mehak M. Khan, Chong Guo, Wade G. Regehr, Nov 1 2020, In: Nature Neuroscience
Citations: 35

A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain
Christopher H. Chen, Leannah N. Newman, Amanda P. Stark, Katherine E. Bond, Dawei Zhang, Stefano Nardone, Charles R. Vanderburg, Naeem M. Nadaf, Zhiyi Yao, Kefiloe Mutume, Isabella Flaquer, Bradford B. Lowell, Evan Z. Macosko, Wade G. Regehr, Nov 2023, In: Nature Neuroscience
Citations: 23

Centers & Institutes

• Neuroscience Institute

• CC Lab
• Elsevier Pure Profile