CCR4-NOT is required for suppressing pervasive transcription and retrotransposable elements
Shardul Kulkarni, Alexis Morrissey, Aswathy Sebastian, Oluwasegun T. Akinniyi, Cheryl A. Keller Capone, Istvan Albert, Shaun Mahony, Joseph C. Reese,
Aug 2026,
In: Journal of Biological Chemistry
Date: Aug 2026
An optimized CRISPR-Cas12a genome-wide screen reveals PTPA phosphatase pathway in fetal hemoglobin silencing
Elizabeth A. Traxler, Quynn Hotan, Yue Shao, Chad A. Komar, Qingzhou Chen, Megan Saari, A. Josephine Thrasher, Shuchen Yang, Kunhua Qin, Michelle Wang, Scott A. Peslak, Osheiza Abdulmalik, Belinda M. Giardine, Cheryl A. Keller, Ross C. Hardison, Andy J. Minn, Eugene Khandros, Junwei Shi, Gerd A. Blo...,
Apr 23 2026,
In: Blood
Date: Apr 23 2026
Highly discriminative globin gene activation by the noncanonical BAF chromatin remodeling complex
Abhirup Bagchi, Sindhu Billakanti, Vanessa Shehu, Kathryn M. Farrell, Sarah A. Cotteta, Bailey N. Godfrey, Micaela Alpert, Jacob Flores Zeranski, Krista A. Budinich, Zhuangzhuang Geng, Osheiza Abdulmalik, Belinda M. Giardine, Cheryl A. Keller, Ross Cameron Hardison, Junwei Shi, Eugene Khandros,
Feb 5 2026,
In: Blood
Date: Feb 5 2026
Gene expression analysis and proximity labeling reveal post-transcriptional functions of the yeast RNA polymerase II regulator Def1
Oluwasegun T. Akinniyi, Shardul Kulkarni, Mikayla M. Hribal, Cheryl A. Keller, Belinda M. Giardine, Joseph C. Reese,
Feb 2026,
In: Journal of Biological Chemistry
Date: Feb 2026
Auxin-induced depletion of human CCR4-NOT subunits reveals opposing functions of CNOT1 and CNOT4 in mRNA metabolism
Shardul Kulkarni, Courtney Smith, Oluwasegun T. Akinniyi, Belinda M. Giardine, Cheryl A. Keller, Alexei Arnaoutov, Joseph C. Reese,
Dec 2025,
In: Journal of Biological Chemistry
Date: Dec 2025
Transcriptome and chromatin accessibility divergence during differentiation of a bipotential progenitor cell population to erythroblasts and megakaryocytes
Tejaswini Mishra, Belinda M. Giardine, Christapher S. Morrissey, Cheryl A. Keller, Elisabeth F. Heuston, Stacie M. Anderson, Vikram R. Paralkar, Maxim Pimkin, Mitchell J. Weiss, David M. Bodine, Ross C. Hardison,
Dec 2025,
In: Journal of Biological Chemistry
Date: Dec 2025
Single-stranded DNA-binding proteins are essential components of the architectural LDB1 protein complex
Xiaokang Wang, Nicholas G. Aboreden, Ying Cai, Jessica C. Lam, Kate A. Henderson, Jiaqi Xiang, Belinda M. Giardine, Ross C. Hardison, Cheryl A. Keller, Lalitha Nagarajan, Stephen J. Brandt, Gerd A. Blobel,
Aug 21 2025,
In: Molecular cell
Date: Aug 21 2025
LDB1 establishes multi-enhancer networks to regulate gene expression
Nicholas G. Aboreden, Jessica C. Lam, Viraat Y. Goel, Siqing Wang, Xiaokang Wang, Susannah C. Midla, Alma Quijano, Cheryl A. Keller, Belinda M. Giardine, Ross C. Hardison, Haoyue Zhang, Anders S. Hansen, Gerd A. Blobel,
Jan 16 2025,
In: Molecular cell
Date: Jan 16 2025
YY1-controlled regulatory connectivity and transcription are influenced by the cell cycle
Jessica C. Lam, Nicholas G. Aboreden, Susannah C. Midla, Siqing Wang, Anran Huang, Cheryl A. Keller, Belinda Giardine, Kate A. Henderson, Ross C. Hardison, Haoyue Zhang, Gerd A. Blobel,
Sep 2024,
In: Nature Genetics
Date: Sep 2024
Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes
Guanjue Xiang, Xi He, Belinda M. Giardine, Kathryn J. Isaac, Dylan J. Taylor, Rajiv C. McCoy, Camden Jansen, Cheryl A. Keller, Alexander Q. Wixom, April Cockburn, Amber Miller, Qian Qi, Yanghua He, Yichao Li, Jens Lichtenberg, Elisabeth F. Heuston, Stacie M. Anderson, Jing Luan, Marit W. Vermunt, Fe...,
Jul 2024,
In: Genome Research
Date: Jul 2024
Expanded encyclopaedias of DNA elements in the human and mouse genomes
Federico Abascal, Reyes Acosta, Nicholas J. Addleman, Jessika Adrian, Veena Afzal, Bronwen Aken, Jennifer A. Akiyama, Omar Al Jammal, Henry Amrhein, Stacie M. Anderson, Gregory R. Andrews, Igor Antoshechkin, Kristin G. Ardlie, Joel Armstrong, Matthew Astley, Budhaditya Banerjee, Amira A. Barkal, If ...,
Jul 30 2020,
In: Nature
Citations: 1,640
A comparative encyclopedia of DNA elements in the mouse genome
Feng Yue, Yong Cheng, Alessandra Breschi, Jeff Vierstra, Weisheng Wu, Tyrone Ryba, Richard Sandstrom, Zhihai Ma, Carrie Davis, Benjamin D. Pope, Yin Shen, Dmitri D. Pervouchine, Sarah Djebali, Robert E. Thurman, Rajinder Kaul, Eric Rynes, Anthony Kirilusha, Georgi K. Marinov, Brian A. Williams, Dian...,
Nov 20 2014,
In: Nature
Citations: 1,386
An encyclopedia of mouse DNA elements (Mouse ENCODE)
John A. Stamatoyannopoulos, Michael Snyder, Ross Hardison, Bing Ren, Thomas Gingeras, David M. Gilbert, Mark Groudine, Michael Bender, Rajinder Kaul, Theresa Canfield, Erica Giste, Audra Johnson, Mia Zhang, Gayathri Balasundaram, Rachel Byron, Vaughan Roach, Peter J. Sabo, Richard Sandstrom, A. Sand...,
Aug 13 2012,
In: Genome biology
Citations: 371
Regulation of GABA<sub>A</sub> receptor trafficking, channel activity, and functional plasticity of inhibitory synapses
Bernhard Lüscher, Cheryl A. Keller,
Jun 2004,
In: Pharmacology and Therapeutics
Citations: 239
Principles of regulatory information conservation between mouse and human
Yong Cheng, Zhihai Ma, Bong Hyun Kim, Weisheng Wu, Philip Cayting, Alan P. Boyle, Vasavi Sundaram, Xiaoyun Xing, Nergiz Dogan, Jingjing Li, Ghia Euskirchen, Shin Lin, Yiing Lin, Axel Visel, Trupti Kawli, Xinqiong Yang, Dorrelyn Patacsil, Cheryl A. Keller, Belinda Giardine, Anshul Kundaje, Ting Wang,...,
Nov 20 2014,
In: Nature
Citations: 234
The γ2 subunit of GABA<sub>A</sub> receptors is a substrate for palmitoylation by GODZ
Cheryl A. Keller, Xu Yuan, Patrizia Panzanelli, Michelle L. Martin, Melissa Alldred, Marco Sassoè-Pognetto, Bernhard Lüscher,
Jun 30 2004,
In: Journal of Neuroscience
Citations: 216
Chromatin structure dynamics during the mitosis-to-G1 phase transition
Haoyue Zhang, Daniel J. Emerson, Thomas G. Gilgenast, Katelyn R. Titus, Yemin Lan, Peng Huang, Di Zhang, Hongxin Wang, Cheryl A. Keller, Belinda Giardine, Ross C. Hardison, Jennifer E. Phillips-Cremins, Gerd A. Blobel,
Dec 5 2019,
In: Nature
Citations: 207
Perspectives on ENCODE
Federico Abascal, Reyes Acosta, Nicholas J. Addleman, Jessika Adrian, Veena Afzal, Bronwen Aken, Jennifer A. Akiyama, Omar Al Jammal, Henry Amrhein, Stacie M. Anderson, Gregory R. Andrews, Igor Antoshechkin, Kristin G. Ardlie, Joel Armstrong, Matthew Astley, Budhaditya Banerjee, Amira A. Barkal, If ...,
Jul 30 2020,
In: Nature
Citations: 163
GODZ-mediated palmitoylation of GABA<sub>A</sub> receptors is required for normal assembly and function of GABAergic inhibitory synapses
Cheng Fang, Lunbin Deng, Cheryl A. Keller, Masaki Fukata, Yuko Fukata, Gong Chen, Bernhard Lüscher,
Dec 6 2006,
In: Journal of Neuroscience
Citations: 151
Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells
Jeremy D. Grevet, Xianjiang Lan, Nicole Hamagami, Christopher R. Edwards, Laavanya Sankaranarayanan, Xinjun Ji, Saurabh K. Bhardwaj, Carolyne J. Face, David F. Posocco, Osheiza Abdulmalik, Cheryl A. Keller, Belinda Giardine, Simone Sidoli, Ben A. Garcia, Stella T. Chou, Stephen A. Liebhaber, Ross C....,
Jul 20 2018,
In: Science
Citations: 133
