Experimental Evidence for Radical-Polar Crossover in Competition with, Rather Than Preceding, Alkene Formation by Microbial Ethylene-Forming Enzyme
Evan J. Burke, Chao Wang, Holly Lussier, Elvira R. Sayfutyarova, Alexey Silakov, Carsten Krebs, J. Martin Bollinger, Jeffrey W. Slater,
Dec 3 2025,
In: Journal of the American Chemical Society
Date: Dec 3 2025
Iron-sulfur clusters in SARS-CoV-2 exoribonuclease and methyltransferase complexes
Nunziata Maio, Umberto Terranova, Yan Li, J. Martin Bollinger, Carsten Krebs, Tracey A. Rouault,
Dec 2025,
In: Nature communications
Date: Dec 2025
A Structurally Divergent Class Ia Ribonucleotide Reductase from a Tick-Borne Pathogen
Olivia M. Peduzzi, Gavin M. Palowitch, John P. Gajewski, Kai Hu, Alyssa Wheeler, Tatiana N. Laremore, Steve Silletti, Elizabeth A. Komives, Benjamin D. Allen, Alexey Silakov, Carsten Krebs, J. Martin Bollinger, Chi Yun Lin, Amie K. Boal,
Sep 16 2025,
In: Biochemistry
Date: Sep 16 2025
Heme Oxygenase–Like Metalloenzymes
Sarah R. Pope, Molly J. McBride, Mrutyunjay A. Nair, Xavier E. Salas-Solá, Carsten Krebs, J. Martin Bollinger, Amie K. Boal,
Jun 20 2025,
In: Annual review of biochemistry
Date: Jun 20 2025
Structural Elucidation of the Reduced Mn(III)/Fe(III) Intermediate of the Radical-Initiating Metallocofactor in Chlamydia trachomatis Ribonucleotide Reductase
Ryan J. Martinie, Jovan Livada, Nyaari Kothiya, J. Martin Bollinger, Carsten Krebs, Alexey Silakov,
Mar 4 2025,
In: Biochemistry
Date: Mar 4 2025
Azetidine amino acid biosynthesis by non-haem iron-dependent enzymes
Yanan Du, Anyarat Thanapipatsiri, Jesús J. Blancas Cortez, Xavier E. Salas-Solá, Chi Yun Lin, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, Kenichi Yokoyama,
2025,
In: Nature Chemistry
Date: 2025
Biochemical Studies of a Cyanobacterial Halogenase Support the Involvement of a Dimetal Cofactor
Michelle L. Wang, Nathaniel R. Glasser, Mrutyunjay A. Nair, Carsten Krebs, J. Martin Bollinger, Emily P. Balskus,
2025,
In: Biochemistry
Date: 2025
Optimized Substrate Positioning Enables Switches in the C−H Cleavage Site and Reaction Outcome in the Hydroxylation−Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase
Eliott S. Wenger, Ryan J. Martinie, Richiro Ushimaru, Christopher J. Pollock, Debangsu Sil, Aaron Li, Nhi Hoang, Gavin M. Palowitch, Brandt P. Graham, Irene Schaperdoth, Evan J. Burke, Ailiena O. Maggiolo, Wei Chen Chang, Benjamin D. Allen, Carsten Krebs, Alexey Silakov, Amie K. Boal, J. Martin Boll...,
Sep 4 2024,
In: Journal of the American Chemical Society
Date: Sep 4 2024
Steric Perturbation of the Grob-like Final Step of Ethylene-Forming Enzyme Enables 3-Hydroxypropionate and Propylene Production
Evan J. Burke, Rachelle A. Copeland, Yash Dixit, Carsten Krebs, J. Martin Bollinger,
Jan 24 2024,
In: Journal of the American Chemical Society
Date: Jan 24 2024
An Unusual Ferryl Intermediate and Its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO
Juan Pan, Eliott S. Wenger, Chi Yun Lin, Bo Zhang, Debangsu Sil, Irene Schaperdoth, Setareh Saryazdi, Robert B. Grossman, Carsten Krebs, J. Martin Bollinger,
2024,
In: Biochemistry
Date: 2024
Non-heme Fe(IV)-oxo intermediates
Carsten Krebs, Danica Galonić Fujimori, Christopher T. Walsh, J. Martin Bollinger,
Jul 2007,
In: Accounts of Chemical Research
Citations: 904
The first direct characterization of a high-valent iron intermediate in the reaction of an α-ketoglutarate-dependent dioxygenase
John C. Price, Eric W. Barr, Bhramara Tirupati, J. Martin Bollinger, Carsten Krebs,
Jun 24 2003,
In: Biochemistry
Citations: 676
IscU as a scaffold for iron-sulfur cluster biosynthesis
Jeffrey N. Agar, Carsten Krebs, Jeverson Frazzon, Boi Hanh Huynh, Dennis R. Dean, Michael K. Johnson,
Jul 11 2000,
In: Biochemistry
Citations: 401
Evidence for Hydrogen Abstraction from C1 of Taurine by the High-Spin Fe(IV) Intermediate Detected during Oxygen Activation by Taurine:α -Ketoglutarate Dioxygenase (TauD)
John C. Price, Eric W. Barr, Timothy E. Glass, Carsten Krebs, J. Martin Bollinger,
Oct 29 2003,
In: Journal of the American Chemical Society
Citations: 384
Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3
Danica P. Galonić, Eric W. Barr, Christopher T. Walsh, J. Martin Bollinger, Carsten Krebs,
Feb 2007,
In: Nature Chemical Biology
Citations: 317
EXAFS spectroscopic evidence for an Fe=O unit in the Fe(IV) intermediate observed during oxygen activation by taurine:α-ketoglutarate dioxygenase
Pamela J. Riggs-Gelasco, John C. Price, Robert B. Guyer, Jessica H. Brehm, Eric W. Barr, J. Martin Bollinger, Carsten Krebs,
Jul 7 2004,
In: Journal of the American Chemical Society
Citations: 298
Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase
Lee M. Hoffart, Eric W. Barr, Robert B. Guyer, J. Martin Bollinger, Carsten Krebs,
Oct 3 2006,
In: Proceedings of the National Academy of Sciences of the United States of America
Citations: 296
Human calprotectin is an iron-sequestering host-defense protein
Toshiki G. Nakashige, Bo Zhang, Carsten Krebs, Elizabeth M. Nolan,
Oct 19 2015,
In: Nature Chemical Biology
Citations: 256
Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2
Megan L. Matthews, Christopher S. Neumann, Linde A. Miles, Tyler L. Grove, Squire J. Booker, Carsten Krebs, Christopher T. Walsh, J. Martin Bollinger,
Oct 20 2009,
In: Proceedings of the National Academy of Sciences of the United States of America
Citations: 229
IscA, an alternate scaffold for Fe-S cluster biosynthesis
C. Krebs, J. N. Agar, A. D. Smith, J. Frazzon, D. R. Dean, B. H. Huynh, M. K. Johnson,
Nov 20 2001,
In: Biochemistry
Citations: 222
