Site-selective protein editing by backbone extension acyl rearrangements
Leah T. Roe, Isabel M. Piper, Carly K. Schissel, Taylor L. Dover, Bhavana Shah, Noah X. Hamlish, Arjun M. Garapaty, Shuai Zheng, Diondra A. Dilworth, Nicole Wong, Zhongqi Zhang, Abhishek Chatterjee, Matthew B. Francis, Scott J. Miller, Alanna Schepartz,
Oct 2025,
In: Nature Chemical Biology
Date: Oct 2025
Programmable protein editing
Carly K. Schissel,
Oct 2025,
In: Trends in Biochemical Sciences
Date: Oct 2025
Monitoring monomer-specific acyl-tRNA levels in cells with PARTI
Meghan A. Pressimone, Carly K. Schissel, Isabella H. Goss, Cameron V. Swenson, Alanna Schepartz,
May 8 2025,
In: Nucleic acids research
Date: May 8 2025
Peptide Backbone Editing via Post-Translational O to C Acyl Shift
Carly K. Schissel, Helena Roberts-Mataric, Isaac J. Garcia, Hana Kang, Riaz Mowzoon-Mogharrabi, Matthew B. Francis, Alanna Schepartz,
Feb 26 2025,
In: Journal of the American Chemical Society
Date: Feb 26 2025
In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery
Carly K. Schissel, Charlotte E. Farquhar, Andrei Loas, Annika B. Malmberg, Bradley L. Pentelute,
Mar 17 2023,
In: ACS chemical biology
Date: Mar 17 2023
Cell-Penetrating d -Peptides Retain Antisense Morpholino Oligomer Delivery Activity
Carly K. Schissel, Charlotte E. Farquhar, Annika B. Malmberg, Andrei Loas, Bradley L. Pentelute,
Apr 20 2022,
In: ACS Bio and Med Chem Au
Date: Apr 20 2022
Total synthesis of himastatin
Kyan A. D’Angelo, Carly K. Schissel, Bradley L. Pentelute, Mohammad Movassaghi,
Feb 25 2022,
In: Science
Date: Feb 25 2022
Automated Flow Synthesis of Peptide-PNA Conjugates
Chengxi Li, Alex J. Callahan, Kruttika S. Phadke, Bryan Bellaire, Charlotte E. Farquhar, Genwei Zhang, Carly K. Schissel, Alexander J. Mijalis, Nina Hartrampf, Andrei Loas, David E. Verhoeven, Bradley L. Pentelute,
Feb 23 2022,
In: ACS Central Science
Date: Feb 23 2022
Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers
Chengxi Li, Alex J. Callahan, Mark D. Simon, Kyle A. Totaro, Alexander J. Mijalis, Kruttika Suhas Phadke, Genwei Zhang, Nina Hartrampf, Carly K. Schissel, Ming Zhou, Hong Zong, Gunnar J. Hanson, Andrei Loas, Nicola L.B. Pohl, David E. Verhoeven, Bradley L. Pentelute,
Dec 1 2021,
In: Nature communications
Date: Dec 1 2021
Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers
Eva M. López-Vidal, Carly K. Schissel, Somesh Mohapatra, Kamela Bellovoda, Chia Ling Wu, Jenna A. Wood, Annika B. Malmberg, Andrei Loas, Rafael Gómez-Bombarelli, Bradley L. Pentelute,
Nov 22 2021,
In: JACS Au
Date: Nov 22 2021
Synthesis of proteins by automated flow chemistry
N. Hartrampf, A. Saebi, M. Poskus, Z. P. Gates, A. J. Callahan, A. E. Cowfer, S. Hanna, S. Antilla, C. K. Schissel, A. J. Quartararo, X. Ye, A. J. Mijalis, M. D. Simon, A. Loas, S. Liu, C. Jessen, T. E. Nielsen, B. L. Pentelute,
May 29 2020,
In: Science
Citations: 294
Deep learning to design nuclear-targeting abiotic miniproteins
Carly K. Schissel, Somesh Mohapatra, Justin M. Wolfe, Colin M. Fadzen, Kamela Bellovoda, Chia Ling Wu, Jenna A. Wood, Annika B. Malmberg, Andrei Loas, Rafael Gómez-Bombarelli, Bradley L. Pentelute,
Oct 2021,
In: Nature Chemistry
Citations: 55
Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers
Chengxi Li, Alex J. Callahan, Mark D. Simon, Kyle A. Totaro, Alexander J. Mijalis, Kruttika Suhas Phadke, Genwei Zhang, Nina Hartrampf, Carly K. Schissel, Ming Zhou, Hong Zong, Gunnar J. Hanson, Andrei Loas, Nicola L.B. Pohl, David E. Verhoeven, Bradley L. Pentelute,
Dec 1 2021,
In: Nature communications
Citations: 51
Engineering Bioactive Dimeric Transcription Factor Analogs via Palladium Rebound Reagents
Muhammad Jbara, Sebastian Pomplun, Carly K. Schissel, Susana Wilson Hawken, Ann Boija, Isaac Klein, Jacob Rodriguez, Stephen L. Buchwald, Bradley L. Pentelute,
Aug 4 2021,
In: Journal of the American Chemical Society
Citations: 42
Automated Flow Synthesis of Peptide-PNA Conjugates
Chengxi Li, Alex J. Callahan, Kruttika S. Phadke, Bryan Bellaire, Charlotte E. Farquhar, Genwei Zhang, Carly K. Schissel, Alexander J. Mijalis, Nina Hartrampf, Andrei Loas, David E. Verhoeven, Bradley L. Pentelute,
Feb 23 2022,
In: ACS Central Science
Citations: 34
Total synthesis of himastatin
Kyan A. D’Angelo, Carly K. Schissel, Bradley L. Pentelute, Mohammad Movassaghi,
Feb 25 2022,
In: Science
Citations: 32
Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription
Sebastian Pomplun, Muhammad Jbara, Carly K. Schissel, Susana Wilson Hawken, Ann Boija, Charles Li, Isaac Klein, Bradley L. Pentelute,
Aug 25 2021,
In: ACS Central Science
Citations: 31
Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers
Eva M. López-Vidal, Carly K. Schissel, Somesh Mohapatra, Kamela Bellovoda, Chia Ling Wu, Jenna A. Wood, Annika B. Malmberg, Andrei Loas, Rafael Gómez-Bombarelli, Bradley L. Pentelute,
Nov 22 2021,
In: JACS Au
Citations: 21
Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy
Colin M. Fadzen, Rebecca L. Holden, Justin M. Wolfe, Zi Ning Choo, Carly K. Schissel, Monica Yao, Gunnar J. Hanson, Bradley L. Pentelute,
Sep 24 2019,
In: Biochemistry
Citations: 15
Secondary Amino Alcohols
Sebastian Pomplun, Christopher R. Shugrue, Adeline M. Schmitt, Carly K. Schissel, Charlotte E. Farquhar, Bradley L. Pentelute,
Jul 6 2020,
In: Angewandte Chemie - International Edition
Citations: 14
