Core for conducting metabolomics studies on variety of biofluids and tissue extracts from plant and animal sources. Provided instruments include Agilent 5975C series GC-MSD, Bruker NEO 600 NMR, Thermo Exactive Plus, Thermo Orbitrap Exploris 120, Thermo Orbitrap Exploris 240, Thermo TSQ Quantis Plus, Thermo Orbitrap Fusion Lumos Tribrid.
RRID
Research Publications Supported by This Facility
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Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistance.
Okombo J, Ndiaye T, Qahash T, Moura IMR, Gil-Iturbe E, Hagenah LM, Bridgford JL, Bonatto V, Ward KE, Yeo T, Narwal SK, Orta LV, Anderson I, Dhingra SK, Pasaje CFA, Park H, Kim J, Guido RVC, Jiménez-Diaz MB, Angulo-Barturen I, Niles JC, Mancia F, Uhlemann AC, Mok S, Quick M, Winzeler EA, Leroy D, Llinás M, Thathy V, Fidock DA
Nat Commun. 2026 Apr 1; 17(1): . doi: 10.1038/s41467-026-70914-1. 2026 Apr 1. -
Natural triterpenic phenolic esters target PfA-M17 in Plasmodium falciparum.
Mamede L, Rangel GW, Schmitt M, Albrecht S, Spichty M, Bero J, Beaufay C, Florent I, Llinás M, Frédérich M, Quetin-Leclercq J
Malar J. 2026 Jan 2; 25(1): 74. doi: 10.1186/s12936-025-05762-3. 2026 Jan 2. -
Nutrient State, Aging, and Diet Modulate SAM50-Dependent Mitochondrial Remodeling and Systemic Metabolic Signatures.
Hinton AO Jr, Masenga SK, Baskerville V, Petrovic M, Rodriguez B, Hubert DL, Miller-Fleming TW, Koo YD, Katti P, Venkhatesh P, Kirabo A, Lopez EG, Crabtree A, Marshall A, Blake C, Dash C, Prasad P, Murphy A, Afolabi J, Phillips MA, Evans C, Scudese E, Schafer JC, Berry J, Mobley BC, Dai DF, Mobley H, Winn NC, Khan MM, Pulatani D, Sorrentino J, Gamble-George J, McReynolds M, Wanjalla C
Res Sq. 2026 Feb 16; (): . pii: rs.3.rs-8704245. doi: 10.21203/rs.3.rs-8704245/v1. 2026 Feb 16. -
A metabolic constraint in de novo NAD+ synthesis drives mucosal inflammation in IBD.
Wehkamp L, Harris DMM, Kim NM, Alsaadi AI, Wu Q, Oumari M, Taubenheim J, Volk V, Credidio G, Koncina E, Mukherjee PK, Tran F, Mekdoud T, Yu M, Sievers LK, Pavlidis P, Powell N, Wang S, Fung I, Waetzig GH, Rousseaux C, Desreumaux P, Rieder F, Letellier E, Waschina S, Meyer TF, Adolph T, D'Haens G, Kaleta C, Feuerhake F, Verstockt B, McReynolds MR, Rosenstiel P, Schreiber S, Aden K
J Crohns Colitis. 2026 May 8; 20(5): . doi: 10.1093/ecco-jcc/jjag043. . -
Circadian tryptophan metabolism contributes to systemic aryl hydrocarbon receptor activity.
Morgan EW, Murray IA, Coslo DM, Patterson AD, Perdew GH
iScience. 2026 Feb 20; 29(2): 114680. doi: 10.1016/j.isci.2026.114680. 2026 Jan 12. -
The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney.
Katti P, Prasad P, Masenga SK, Venkhatesh P, Vue Z, Marshall AG, Rodriguez B, Le H, Garza-Lopez E, Murphy A, Jenkins B, Kadam A, Shao J, Crabtree A, Martin P, Evans C, Phillips MA, Hubert D, Wandira N, Ochayi OM, Tomar D, Williams CR, Gaddy J, Tomeau B, Bell L, Gillyard T, Hamilton M, Sharma V, Khan MM, Zaganjor E, Ajijola OA, Scudese E, Miller Fleming TW, Kinder A, Dash C, Quintana AM, Mobley BC, Berry JD, Jadiya P, Dai DF, Kirabo A, Kovtun O, Schafer JC, Schaffer S, Pereira RO, Murray DD, Gamble-George J, McReynolds MR, Hinton A Jr
Aging Cell. 2026 May; 25(5): e70534. doi: 10.1111/acel.70534. . -
TACO1 regulates mitochondrial adaptation in hypertension-induced cardiac remodeling and heart failure.
Vetha BSS, McMillan R, Marchant J, Khan MM, Gamble-George J, Afolabi J, Garza-Lopez E, Marshall AG, Perez CPH, Garbrandt D, Mobley B, Schafer J, Kushner M, Kovtun O, Murray DD, Zeczycki T, Kirabo A, Colas A, Wanjalla C, Dai DF, McReynolds M, Aileru A, Hinton A Jr
Res Sq. 2026 May 5; (): . pii: rs.3.rs-9589283. doi: 10.21203/rs.3.rs-9589283/v1. 2026 May 5. -
Phytochemical Composition of Clonally Propagated Artemisia annua L. in Different Geographical Locations and Its Commercial Supplement Quality.
Towler MJ, Kellogg JJ, Weathers PJ
Molecules. 2026 May 28; 31(11): . doi: 10.3390/molecules31111854. 2026 May 28. -
Double Mutations in Plasmodium falciparum Kelch13 drive resistance to next-generation artemisinin derivatives in malaria parasites.
Bower-Lepts C, Ward KE, Wittlin S, Stokes BH, Yeo T, Qahash T, Small-Saunders JL, Park H, Uhlemann AC, Llinás M, Fidock DA, Mok S
bioRxiv. 2026 Apr 3; (): . pii: 2026.04.02.716214. doi: 10.64898/2026.04.02.716214. 2026 Apr 3. -
The making of a queen: Hormonal regulation of female caste in the social bee Bombus impatiens.
Hasani SAM, Derstine N, Santos PK, Amsalem E
Insect Biochem Mol Biol. 2026 Jun; 191(): 104558. doi: 10.1016/j.ibmb.2026.104558. 2026 Apr 12. -
Interkingdom glycine conjugates of indole-3-carboxylates are Ah receptor ligands.
Morgan EW, Annalora AJ, Coslo DM, Gowda K, Desai D, Dong F, Davis EW, Murray IA, Hao F, Koo I, Petersen KS, Kris-Etherton PM, Wolfe T, Erickson R, Walk ST, Bisanz JE, Amin SG, Marcus CB, Patterson AD, Perdew GH
bioRxiv. 2026 Feb 18; (): . pii: 2026.02.13.705761. doi: 10.64898/2026.02.13.705761. 2026 Feb 18. -
Effect of Stereochemistry on the Antiplasmodial Activity and Metabolomic Profile of Novel Tadalafil Analogues.
Elhalawaty EA, Alseedy HA, Woodland JG, Wicht KJ, Swart T, Rangel GW, Hoppe HC, Chibale K, Llinás M, Abadi AH, Ahmed NS
ACS Med Chem Lett. 2026 May 14; 17(5): 1067-1077. doi: 10.1021/acsmedchemlett.6c00009. 2026 Apr 14. -
Metabolomics reveals potentiated metabolic perturbations induced by antimalarial drug combinations against Plasmodium falciparum in vitro.
Eya'ane Meva F, Qahash T, Arinaga J, Llinás M
Exp Parasitol. 2026 Jul 17; 288(): 109171. doi: 10.1016/j.exppara.2026.109171. 2026 Jul 17. -
A Novel Class of Orally Bioavailable Phenylglycine-Benzoxaborole Conjugates with Antimalarial Activity and Potentially Novel Mechanism of Action.
Morake M, Taylor D, Coertzen D, Njoroge M, Krugmann L, Leshabane M, da Rocha S, Qahash T, Girling G, Coyle R, Lee MCS, Wittlin S, Llinás M, Birkholtz LM, Basarab GS, Chibale K
ACS Med Chem Lett. 2026 Jan 8; 17(1): 22-31. doi: 10.1021/acsmedchemlett.5c00549. 2025 Dec 11. -
Systemic rhythmicity of host and bacterial bile acid amidates in the mouse.
Reilly ER, Charron-Lamoureux V, Mannochio-Russo H, Morgan EW, Boyle NR, Koo I, Coudriet E, Hao F, Mohanty I, Perdew GH, Dorrestein PC, Patterson AD
Cell Syst. 2026 Apr 15; 17(4): 101541. doi: 10.1016/j.cels.2026.101541. 2026 Mar 26. -
Glucuronidation metabolomic fingerprinting to map host-microbe metabolism.
Boyle NR, Sekela JJ, Wang M, Mannochio-Russo H, Pyo JJ, Kim MS, Tian S, Koo I, Friedman ES, Tanes C, Anitha M, Tian Y, Morgan EW, Murray IA, Zackular JP, Bittinger K, Lewis JD, Perdew GH, Wu GD, Zemel BS, Dorrestein PC, Bisanz JE, Redinbo MR, Patterson AD
Nat Commun. 2026 May 20; 17(1): . doi: 10.1038/s41467-026-73398-1. 2026 May 20. -
Tracing NAD(+) metabolism uncovers adaptive coordination between host and microbiome during colitis.
Alsaadi AI, Wehkamp L, Pothakamury AA, Yahia MS, Prasad P, Gilloteau C, Sadler J, Smith JD, Jenkins BC, Diven GS, Bornhäuser J, Mekdoud T, Tian S, Rosenstiel P, Schreiber S, Bisanz JE, Aden K, McReynolds MR
Cell Rep. 2026 Jul 25; 45(8): 117730. doi: 10.1016/j.celrep.2026.117730. 2026 Jul 25. -
Sequestration of plant defenses by spotted lanternfly (Lycorma delicatula) and effects on avian predators.
Johnson AE, Cornell A, Zhu F, Shay AE, Davis G, Hoover K
J Chem Ecol. 2025 Oct 23; 51(6): 102. doi: 10.1007/s10886-025-01647-6. 2025 Oct 23. -
Metabolomic, Lipidomic, and Enterohormone Changes in the Progression from MASLD to MASH.
Rivas JA, Murphy AC, Prasad P, Goitom SS, Romero AS, Enriquez CM, Maes BB, Akepati PR, Garcia MA, Lauer FT, Gullapalli RR, Gonzales KM, Gross JM, Pu J, Leng S, In JG, McReynolds MR, Castillo EF
bioRxiv. 2025 Sep 18; (): . pii: 2025.09.16.676598. doi: 10.1101/2025.09.16.676598. 2025 Sep 18. -
10 degree C static storage of porcine donation after circulatory death livers improves biliary viability and mitigates ischemia-reperfusion injury.
Tracy KM, Shishido Y, Petrovic M, Murphy A, Adesanya T, Fortier AK, Harris TR, Cortelli M, Tucker WD, François SA, Petree B, Raietparvar K, Simon V, Johnson CA Jr, Simonds E, Poland J, Glomp GA, Crannell C, Liang J, Marshall A, Hinton A Jr, Shaver CM, Demarest CT, Ukita R, Shah AS, Rizzari M, Montenovo M, Rauf MA, McReynolds M, Bacchetta M
Am J Transplant. 2025 Jul; 25(7): 1417-1431. doi: 10.1016/j.ajt.2025.03.018. 2025 Mar 20. -
The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria.
Woodland JG, Coertzen D, Wicht KJ, Hidalgo VF, Pasaje CFA, Godoy LC, Qahash T, Mmonwa MM, Dziwornu GA, Wambua L, Harries S, Korkor CM, Njoroge M, Krugmann L, Taylor D, Leshabane M, Langeveld H, Rabie T, Reader J, van der Watt M, Venter N, Erlank E, Aswat AS, Koekemoer LL, Yeo T, Jeon JH, Fidock DA, Gamo FJ, Wittlin S, Niles JC, Llinas M, Coulson LB, Birkholtz LM, Chibale K
Angew Chem Int Ed Engl. 2025 Jul 7; 64(28): e202425206. doi: 10.1002/anie.202425206. 2025 May 15. -
The activity of soil microbial taxa in the rhizosphere predicts the success of root colonization.
Harris JE, Bledsoe RB, Guha S, Omari H, Crandall SG, Burghardt LT, Couradeau E
mSystems. 2025 Sep 23; 10(9): e0045825. doi: 10.1128/msystems.00458-25. 2025 Aug 6. -
Effects of Hot Air Drying on the Nutritional and Phytochemical Composition of Radish (Raphanus sativus L.) Microgreens.
Jauregui MJ, Warren ER, Di Gioia F, Kwasniewski MT, Lambert JD
J Food Sci. 2025 Jul; 90(7): e70426. doi: 10.1111/1750-3841.70426. . -
Bioactive compound identification without fractionation: an Ocimum spp. case study.
Abraham EJ, Custer K, Jordan RT, Kellogg JJ
Metabolomics. 2025 Nov 15; 21(6): 166. doi: 10.1007/s11306-025-02369-2. 2025 Nov 15. -
NAD(+) depletion drives age-related monocyte hyperinflammation after stroke and is reversed by nicotinamide riboside.
Cabrera M, Eastman B, Ennerfelt H, Alsaadi AI, Alexandrova L, Ay YA, Huang J, Wang Q, Blacher E, McReynolds MR, Andreasson KI, Iweka CA
J Neuroinflammation. 2025 Nov 27; 23(1): 7. doi: 10.1186/s12974-025-03638-6. 2025 Nov 27. -
Hexosamine biosynthesis disruption impairs GPI production and arrests Plasmodium falciparum growth at schizont stages.
Alberione MP, Avalos-Padilla Y, Rangel GW, Ramírez M, Romero-Uruñuela T, Fenollar À, Ortega-Barrionuevo J, Crispim M, Smith TK, Llinás M, Izquierdo L
PLoS Pathog. 2025 Jul; 21(7): e1012832. doi: 10.1371/journal.ppat.1012832. 2025 Jul 3. -
A synthetic gut microbiota provides an understanding of the maintenance and functional impact of phage.
Koo H, Heber K, Tian S, Connolly ST, Hao F, Zhao J, Swencki-Underwood B, Patterson AD, Townsend GE, Bisanz JE
mBio. 2025 Dec 10; 16(12): e0234125. doi: 10.1128/mbio.02341-25. 2025 Nov 12. -
Effect of Varying Quantities of Lean Beef as Part of a Mediterranean-Style Dietary Pattern on Gut Microbiota and Plasma, Fecal, and Urinary Metabolites: A Randomized Crossover Controlled Feeding Trial.
DiMattia ZS, Zhao J, Hao F, Koshkin S, Bisanz JE, Patterson AD, Fleming JA, Kris-Etherton PM, Petersen KS
J Am Heart Assoc. 2025 Oct 7; 14(19): e041063. doi: 10.1161/JAHA.125.041063. 2025 Sep 19. -
Tracing NAD(+) metabolism uncovers adaptive coordination between host and microbiome during colitis.
Alsaadi AI, Welz L, Pothakamury AA, Gilloteau C, Prasad P, Yahia MS, Sadler J, Smith JD, Jenkins BC, Diven GS, Bornhäuser J, Mekdoud T, Tian S, Rosenstiel P, Schreiber S, Bisanz JE, Aden K, McReynolds MR
Res Sq. 2025 Dec 4; (): . pii: rs.3.rs-8195970. doi: 10.21203/rs.3.rs-8195970/v1. 2025 Dec 4. -
The role of MICOS in modulating mitochondrial dynamics and structural changes in vulnerable regions of Alzheimer's Disease.
Shao B, Kula B, Le H, Venkhatesh P, Katti P, Marshall AG, Chittaranjan S, Thapilyal S, Namdar HK, Nivedya C, Roszczyk A, Mobley H, Killion M, St John E, Martin P, Rodrigiuez B, Hamilton M, Bell L, Wyckoff SM, Moran LA, Philips M, Hubert D, Tomeau B, Afolabi JM, Kirabo A, Blanco I, Reasonover S, Drake LE, Lippmann ES, Evans C, Santisteban MM, Cheairs TG, Mesenga S, Wanjalla C, Gaddy J, McMillan R, Hernandez Perez CP, Paing HH, Schafer JC, Mobley B, Berry J, Crabtree A, Kovtun O, Goodwin S, Garza Lopez E, Dash C, Dai DF, Miller-Fleming TW, Hinton A Jr, Smith NA
bioRxiv. 2025 Dec 16; (): . pii: 2025.12.13.693635. doi: 10.64898/2025.12.13.693635. 2025 Dec 16. -
Glucuronidation Metabolomic Fingerprinting to Map Host-Microbe Metabolism.
Patterson A, Boyle N, John J, Wang M, Mannochio-Russo H, Pyo JJ, Kim MS, Tian S, Koo I, Anitha M, Tian Y, Morgan E, Murray I, Perdew G, Wu G, Dorrestein P, Bisanz J, Redinbo M
Res Sq. 2025 Apr 8; (): . pii: rs.3.rs-6321321. doi: 10.21203/rs.3.rs-6321321/v1. 2025 Apr 8. -
The plasmepsin-piperaquine paradox persists in Plasmodium falciparum.
Walsh B, Summers RL, Rangel GW, Hagenah LM, Mok S, Llinás M, Fidock DA, Wirth DF, Bopp S
PLoS Pathog. 2025 Jul; 21(7): e1012779. doi: 10.1371/journal.ppat.1012779. 2025 Jul 28. -
Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistance.
Okombo J, Ndiaye T, Qahash T, Moura IMR, Gil-Iturbe E, Hagenah LM, Bridgford JL, Bonatto V, Ward KE, Yeo T, Narwal SK, Orta LV, Anderson I, Dhingra SK, Pasaje CFA, Park H, Kim J, Guido RVC, Angulo-Barturen I, Niles JC, Mancia F, Uhlemann AC, Mok S, Quick M, Winzeler EA, Leroy D, Llinás M, Thathy V, Fidock DA
Res Sq. 2025 Oct 9; (): . pii: rs.3.rs-7697517. doi: 10.21203/rs.3.rs-7697517/v1. 2025 Oct 9. -
Multiple, redundant carboxylic acid transporters support mitochondrial metabolism in Plasmodium falciparum.
Rajaram K, Rangel GW, Munro JT, Nair SC, Elahi R, Llinás M, Prigge ST
J Biol Chem. 2025 Jul; 301(7): 110248. doi: 10.1016/j.jbc.2025.110248. 2025 May 19. -
Metabolite profiling of Artemisia afra and Artemisia annua extracts reveals divergent effects on Plasmodium falciparum.
Mamede L, Rangel GW, Shinyuy LM, Boussif N, Herent MF, Govaerts B, Jansen O, Ledoux A, De Tullio P, Quetin-Leclercq J, Llinás M, Frédérich M
Phytomedicine. 2025 Jan; 136(): 156361. doi: 10.1016/j.phymed.2025.156361. 2025 Jan 1. -
Targeted and Untargeted Mass Spectrometry Do Not Detect Grayanane-Type Toxins in Monotropa uniflora L.
Anez SG, Flail DB, Burkhart EP, Kellogg JJ
J Nat Prod. 2025 Oct 24; 88(10): 2540-2545. doi: 10.1021/acs.jnatprod.5c00805. 2025 Sep 22. -
Library Enabling Annotation of Botanical Natural Products (LEAFBot): An Open-Access Library of Mass Spectrometry Fragmentation Spectra for Plant Metabolites.
Anderson VM, Ranaweera MM, Jarmusch AK, Shay AE, Todd DA, Cech NB, Kellogg JJ
J Am Soc Mass Spectrom. 2025 May 7; 36(5): 926-929. doi: 10.1021/jasms.5c00038. 2025 Apr 18. -
Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake.
Myers JW, Park WY, Eddie AM, Shinde AB, Prasad P, Murphy AC, Leonard MZ, Pinette JA, Rampy JJ, Montufar C, Shaikh Z, Hickman TT, Reynolds GN, Winn NC, Lantier L, Peck SH, Coate KC, Stein RW, Carrasco N, Calipari ES, McReynolds MR, Zaganjor E
bioRxiv. 2024 Nov 1; (): . pii: 2024.10.28.620705. doi: 10.1101/2024.10.28.620705. 2024 Nov 1. -
MICOS Complex Loss Governs Age-Associated Murine Mitochondrial Architecture and Metabolism in the Liver, While Sam50 Dictates Diet Changes.
Vue Z, Murphy A, Le H, Neikirk K, Garza-Lopez E, Marshall AG, Mungai M, Jenkins B, Vang L, Beasley HK, Ezedimma M, Manus S, Whiteside A, Forni MF, Harris C, Crabtree A, Albritton CF, Jamison S, Demirci M, Prasad P, Oliver A, Actkins KV, Shao J, Zaganjor E, Scudese E, Rodriguez B, Koh A, Rabago I, Moore JE, Nguyen D, Aftab M, Kirk B, Li Y, Wandira N, Ahmad T, Saleem M, Kadam A, Katti P, Koh HJ, Evans C, Koo YD, Wang E, Smith Q, Tomar D, Williams CR, Sweetwyne MT, Quintana AM, Phillips MA, Hubert D, Kirabo A, Dash C, Jadiya P, Kinder A, Ajijola OA, Miller-Fleming TW, McReynolds MR, Hinton A Jr
bioRxiv. 2024 Jul 3; (): . pii: 2024.06.20.599846. doi: 10.1101/2024.06.20.599846. 2024 Jul 3. -
Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) in Keratinocytes by Endogenous Fatty Acids.
Zhu B, Zhu X, Borland MG, Ralph DH, Chiaro CR, Krausz KW, Ntambi JM, Glick AB, Patterson AD, Perdew GH, Gonzalez FJ, Peters JM
Biomolecules. 2024 May 21; 14(6): . doi: 10.3390/biom14060606. 2024 May 21. -
High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model.
Anderson BD, Sepulveda DE, Nachnani R, Cortez-Resendiz A, Coates MD, Beckett A, Bisanz JE, Kellogg JJ, Raup-Konsavage WM
J Pharmacol Exp Ther. 2024 Aug 19; 390(3): 331-341. doi: 10.1124/jpet.124.002204. 2024 Aug 19. -
MULTIPLE, REDUNDANT CARBOXYLIC ACID TRANSPORTERS SUPPORT MITOCHONDRIAL METABOLISM IN PLASMODIUM FALCIPARUM.
Rajaram K, Rangel GW, Munro JT, Nair SC, Llinás M, Prigge ST
bioRxiv. 2024 Nov 27; (): . pii: 2024.11.26.624872. doi: 10.1101/2024.11.26.624872. 2024 Nov 27. -
The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney.
Katti P, Prasad P, Masenga SK, Venkhatesh P, Vue Z, Marshall AG, Rodriguez B, Le H, Garza-Lopez E, Murphy A, Jenkins B, Kadam A, Shao J, Crabtree A, Martin P, Evans C, Phillips MA, Hubert D, Wandira N, Ochayi OM, Tomar D, Williams CR, Gaddy J, Tomeau B, Bell L, Gillyard T, Hamilton M, Sharma V, Khan MM, Zaganjor E, Ajijola OA, Scudese E, Miller Fleming TW, Kinder A, Dash C, Quintana AM, Mobley BC, Berry JD, Jadiya P, Dai DF, Kirabo A, Kovtun O, Schafer JC, Schaffer S, Pereira RO, McReynolds MR, Hinton A Jr
bioRxiv. 2026 Mar 5; (): . pii: 2024.06.09.598108. doi: 10.1101/2024.06.09.598108. 2026 Mar 5. -
Effect of Hemp Extraction Procedures on Cannabinoid and Terpenoid Composition.
Chacon FT, Raup-Konsavage WM, Vrana KE, Kellogg JJ
Plants (Basel). 2024 Aug 10; 13(16): . doi: 10.3390/plants13162222. 2024 Aug 10. -
HIV persists in late coronary atheroma and is associated with increased local inflammation and disease progression.
Obare LM, Bailin SS, Zhang X, Nthenge K, Priest S, Liu Q, Stolze LK, Sheng Q, Gangula R, Behrens M, Jenkins B, Prasad P, Neikirk K, Prakash P, Hogan M, Zhang L, Beasley HK, Shao J, Miller-Fleming TW, Actkins KV, Phillips MA, Hubert D, Malone J, Labeeb C, Gelbard A, Chaillon A, Mashayekhi M, Gabriel CL, Temu T, Olson L, Jones A, Beeri K, Baker P, Kawai K, Ghosh SKB, Guo L, Virmani R, Finn A, Shah P, Yang TS, Bick AG, Kirabo A, Su YR, Phillips EJ, Mallal S, Dash C, Koethe JR, Gianella S, McReynolds MR, Absi T, Hinton A, Wanjalla CN
Res Sq. 2024 Oct 18; (): . pii: rs.3.rs-5125826. doi: 10.21203/rs.3.rs-5125826/v1. 2024 Oct 18. -
Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and Host Metabolic Homeostasis in C57BL/6J Mice.
Tian Y, Rimal B, Bisanz JE, Gui W, Wolfe TM, Koo I, Murray IA, Nettleford SK, Yokoyama S, Dong F, Koshkin S, Prabhu KS, Turnbaugh PJ, Walk ST, Perdew GH, Patterson AD
Environ Health Perspect. 2024 Aug; 132(8): 87005. doi: 10.1289/EHP13356. 2024 Aug 14. -
Human genetics identify convergent signals in mitochondrial LACTB-mediated lipid metabolism in cardiovascular-kidney-metabolic syndrome.
Li S, Liu H, Hu H, Ha E, Prasad P, Jenkins BC, Das US, Mukherjee S, Shishikura K, Hu R, Rader DJ, Pei L, Baur JA, Matthews ML, FitzGerald GA, McReynolds MR, Susztak K
Cell Metab. 2025 Jan 7; 37(1): 154-168.e7. doi: 10.1016/j.cmet.2024.10.007. 2024 Nov 18. -
An O-methylflavone from Artemisia afra kills non-replicating hypoxic Mycobacterium tuberculosis.
Kellogg JJ, Alonso MN, Jordan RT, Xiao J, Cafiero JH, Bush T, Chen X, Towler M, Weathers P, Shell SS
J Ethnopharmacol. 2024 Oct 28; 333(): 118500. doi: 10.1016/j.jep.2024.118500. 2024 Jun 27.