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Thermo QExactive

A Quadrupole-Orbitrap mass spectrometer

Proteomics and Mass Spectrometry Facility

221 Frear South
150 Old Coaly Way
University Park, PA 16802

Phone: 814-863-3503

Penn State shield logo featuring a stylized mountain lion in white and light blue on a blue gradient with white s-curve background.

Uses

Small molecules, peptides and proteins, carbohydrate and nucleic acid oligomers, nucleotides, lipids, and other compounds amenable to ESI or APCI. Quantitative analysis (SIM, PRM)

Specifications

  • Resolving power up to 140,000 FWHM
  • < 1 ppm mass accuracy, HCD fragmentation (MS/MS)
  • extended mass range (up to 6,000 m/z)
  • Triple quadrupole-equivalent ability to quantify compounds

Details

The mass spectrometer can be interfaced with a Vanquish Flex UHPLC system for LC-MS and LC-MS/MS analyses.

Acknowledgement

Users of this instrument are required to acknowledge the Huck Institutes’ Proteomics and Mass Spectrometry Core Facility (RRID: SCR_024462) in any resulting publications. Please review the acknowledgment and co-authorship guidelines for full details.