Guy Townsend

Assistant Professor of Biochemistry and Molecular Biology

H171 Biochemistry & Molecular Biology
Hershey, PA
gxt191@psu.edu

Huck Affiliations

Microbiome Center

Publication Tags

Bacteroides Thetaiotaomicron Proteins Bacteria Genes Polysaccharides Nutrients Carbohydrates Dietary Sugars Growth Bacteroides Food Phosphotransferases Chondroitin Sulfates Glucose Dietary Fiber Gastrointestinal Microbiome Fructose Peptide Elongation Factor G Sodium Hydroxide Gtp Phosphohydrolases Sodium Chloride Protein Synthesis Dietary Sucrose Araban Diet

Most Recent Publications

Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity

Weiwei Han, Bee Zen Peng, Chunyan Wang, Guy E. Townsend, Natasha A. Barry, Frank Peske, Andrew L. Goodman, Jun Liu, Marina V. Rodnina, Eduardo A. Groisman, 2022, EMBO Journal

Erratum: A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor(mBio 11, 1, e03221-19, 2020, 10.1128/mBio.03221-19)

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio

A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio

Dietary sugar silences a colonization factor in a mammalian gut symbiont

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Varsha Raghavan, Natasha A. Barry, Andrew L. Goodman, Eduardo A. Groisman, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 233-238

Erratum: Dietary sugar silences a colonization factor in a mammalian gut symbiont (Proceedings of the National Academy of Sciences of the United States of America (2019) 116 (233–238) DOI: 10.1073/pnas.1813780115)

Prioritization of polysaccharide utilization and control of regulator activation in Bacteroides thetaiotaomicron

Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2017, Molecular Microbiology on p. 32-45

Multiple signals govern utilization of a polysaccharide in the gut bacterium bacteroides thetaiotaomicron

Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2016, mBio

Tuning transcription of nutrient utilization genes to catabolic rate promotes growth in a gut bacterium

Varsha Raghavan, Elisabeth C. Lowe, Guy E. Townsend, David N. Bolam, Eduardo A. Groisman, 2014, Molecular Microbiology on p. 1010-1025

Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems

Guy E. Townsend, Varsha Raghavan, Igor Zwir, Eduardo A. Groisman, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. E161-E169

Identification and characterization of KpsS, a novel polysaccharide sulphotransferase in Mesorhizobium loti

Guy E. Townsend, David H. Keating, 2008, Molecular Microbiology on p. 1149-1164

Most-Cited Papers

Dietary sugar silences a colonization factor in a mammalian gut symbiont

Tuning transcription of nutrient utilization genes to catabolic rate promotes growth in a gut bacterium

Varsha Raghavan, Elisabeth C. Lowe, Guy E. Townsend, David N. Bolam, Eduardo A. Groisman, 2014, Molecular Microbiology on p. 1010-1025

Multiple signals govern utilization of a polysaccharide in the gut bacterium bacteroides thetaiotaomicron

Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2016, mBio

Prioritization of polysaccharide utilization and control of regulator activation in Bacteroides thetaiotaomicron

Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2017, Molecular Microbiology on p. 32-45

Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems

Guy E. Townsend, Varsha Raghavan, Igor Zwir, Eduardo A. Groisman, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. E161-E169

A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio

Erratum: A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor(mBio 11, 1, e03221-19, 2020, 10.1128/mBio.03221-19)

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio

Erratum: Dietary sugar silences a colonization factor in a mammalian gut symbiont (Proceedings of the National Academy of Sciences of the United States of America (2019) 116 (233–238) DOI: 10.1073/pnas.1813780115)

Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity

Weiwei Han, Bee Zen Peng, Chunyan Wang, Guy E. Townsend, Natasha A. Barry, Frank Peske, Andrew L. Goodman, Jun Liu, Marina V. Rodnina, Eduardo A. Groisman, 2022, EMBO Journal

News Articles Featuring Guy Townsend

Sep 24, 2020

Penn State Microbiome Center elects new executive committee

The Penn State Microbiome Center in the Huck Institutes of the Life Sciences recently elected six new members to join its executive committee. The new members, along with 11 others who remained on the committee, started their two-year term in July.

Full Article