Guy Townsend
Assistant Professor of Biochemistry and Molecular Biology

-
H171 Biochemistry & Molecular Biology
Hershey, PA - gxt191@psu.edu
Huck Affiliations
Publication Tags
Bacteroides Thetaiotaomicron Proteins Bacteria Genes Polysaccharides Nutrients Carbohydrates Dietary Sugars Growth Bacteroides Food Phosphotransferases Chondroitin Sulfates Glucose Dietary Fiber Gastrointestinal Microbiome Fructose Peptide Elongation Factor G Sodium Hydroxide Gtp Phosphohydrolases Sodium Chloride Protein Synthesis Dietary Sucrose Araban DietMost Recent Publications
Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity
Weiwei Han, Bee Zen Peng, Chunyan Wang, Guy E. Townsend, Natasha A. Barry, Frank Peske, Andrew L. Goodman, Jun Liu, Marina V. Rodnina, Eduardo A. Groisman, 2022, EMBO Journal
Erratum: A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor(mBio 11, 1, e03221-19, 2020, 10.1128/mBio.03221-19)
Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio
A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor
Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio
Dietary sugar silences a colonization factor in a mammalian gut symbiont
Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Varsha Raghavan, Natasha A. Barry, Andrew L. Goodman, Eduardo A. Groisman, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 233-238
Erratum: Dietary sugar silences a colonization factor in a mammalian gut symbiont (Proceedings of the National Academy of Sciences of the United States of America (2019) 116 (233–238) DOI: 10.1073/pnas.1813780115)
Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Varsha Raghavan, Natasha A. Barry, Andrew L. Goodman, Eduardo A. Groisman, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 5831
Prioritization of polysaccharide utilization and control of regulator activation in Bacteroides thetaiotaomicron
Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2017, Molecular Microbiology on p. 32-45
Multiple signals govern utilization of a polysaccharide in the gut bacterium bacteroides thetaiotaomicron
Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2016, mBio
Tuning transcription of nutrient utilization genes to catabolic rate promotes growth in a gut bacterium
Varsha Raghavan, Elisabeth C. Lowe, Guy E. Townsend, David N. Bolam, Eduardo A. Groisman, 2014, Molecular Microbiology on p. 1010-1025
Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems
Guy E. Townsend, Varsha Raghavan, Igor Zwir, Eduardo A. Groisman, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. E161-E169
Identification and characterization of KpsS, a novel polysaccharide sulphotransferase in Mesorhizobium loti
Guy E. Townsend, David H. Keating, 2008, Molecular Microbiology on p. 1149-1164
Most-Cited Papers
Dietary sugar silences a colonization factor in a mammalian gut symbiont
Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Varsha Raghavan, Natasha A. Barry, Andrew L. Goodman, Eduardo A. Groisman, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 233-238
Tuning transcription of nutrient utilization genes to catabolic rate promotes growth in a gut bacterium
Varsha Raghavan, Elisabeth C. Lowe, Guy E. Townsend, David N. Bolam, Eduardo A. Groisman, 2014, Molecular Microbiology on p. 1010-1025
Multiple signals govern utilization of a polysaccharide in the gut bacterium bacteroides thetaiotaomicron
Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2016, mBio
Prioritization of polysaccharide utilization and control of regulator activation in Bacteroides thetaiotaomicron
Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2017, Molecular Microbiology on p. 32-45
Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems
Guy E. Townsend, Varsha Raghavan, Igor Zwir, Eduardo A. Groisman, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. E161-E169
A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor
Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio
Erratum: A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor(mBio 11, 1, e03221-19, 2020, 10.1128/mBio.03221-19)
Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio
Erratum: Dietary sugar silences a colonization factor in a mammalian gut symbiont (Proceedings of the National Academy of Sciences of the United States of America (2019) 116 (233–238) DOI: 10.1073/pnas.1813780115)
Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Varsha Raghavan, Natasha A. Barry, Andrew L. Goodman, Eduardo A. Groisman, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 5831
Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity
Weiwei Han, Bee Zen Peng, Chunyan Wang, Guy E. Townsend, Natasha A. Barry, Frank Peske, Andrew L. Goodman, Jun Liu, Marina V. Rodnina, Eduardo A. Groisman, 2022, EMBO Journal