Guy Townsend

Assistant Professor of Biochemistry and Molecular Biology

Guy Townsend

Huck Affiliations

Publication Tags

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Bacteroides Thetaiotaomicron Proteins Bacteria Polysaccharides Genes Nutrients Carbohydrates Gastrointestinal Microbiome Bacteroides Dietary Sugars Growth Glucose Health Dietary Fiber Fructose Food Peptide Elongation Factor G Gtp Phosphohydrolases Dietary Sucrose Microorganisms Protein Synthesis Araban Diet Transcription Factors Chondroitin Sulfates

Most Recent Publications

Harnessing gut microbes for glycan detection and quantification

Jennifer L. Modesto, Victoria H. Pearce, Guy E. Townsend, 2023, Nature Communications

Bacteria require phase separation for fitness in the mammalian gut

Emilia Krypotou, Guy E. Townsend, Xiaohui Gao, Shoichi Tachiyama, Jun Liu, Nick D. Pokorzynski, Andrew L. Goodman, Eduardo A. Groisman, 2023, Science

Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity

Weiwei Han, Bee Zen Peng, Chunyan Wang, Guy E. Townsend, Natasha A. Barry, Frank Peske, Andrew L. Goodman, Jun Liu, Marina V. Rodnina, Eduardo A. Groisman, 2023, EMBO Journal

Dietary sugars silence the master regulator of carbohydrate utilization in human gut Bacteroides species

Victoria H. Pearce, Eduardo A. Groisman, Guy E. Townsend, 2023, Gut Microbes

Erratum: A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor(mBio 11, 1, e03221-19, 2020, 10.1128/mBio.03221-19)

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio

A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio

Dietary sugar silences a colonization factor in a mammalian gut symbiont

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Varsha Raghavan, Natasha A. Barry, Andrew L. Goodman, Eduardo A. Groisman, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 233-238

Erratum: Dietary sugar silences a colonization factor in a mammalian gut symbiont (Proceedings of the National Academy of Sciences of the United States of America (2019) 116 (233–238) DOI: 10.1073/pnas.1813780115)

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Varsha Raghavan, Natasha A. Barry, Andrew L. Goodman, Eduardo A. Groisman, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 5831

Prioritization of polysaccharide utilization and control of regulator activation in Bacteroides thetaiotaomicron

Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2017, Molecular Microbiology on p. 32-45

Multiple signals govern utilization of a polysaccharide in the gut bacterium bacteroides thetaiotaomicron

Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2016, mBio

Most-Cited Papers

Dietary sugar silences a colonization factor in a mammalian gut symbiont

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Varsha Raghavan, Natasha A. Barry, Andrew L. Goodman, Eduardo A. Groisman, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 233-238

Multiple signals govern utilization of a polysaccharide in the gut bacterium bacteroides thetaiotaomicron

Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2016, mBio

Tuning transcription of nutrient utilization genes to catabolic rate promotes growth in a gut bacterium

Varsha Raghavan, Elisabeth C. Lowe, Guy E. Townsend, David N. Bolam, Eduardo A. Groisman, 2014, Molecular Microbiology on p. 1010-1025

Prioritization of polysaccharide utilization and control of regulator activation in Bacteroides thetaiotaomicron

Nathan D. Schwalm, Guy E. Townsend, Eduardo A. Groisman, 2017, Molecular Microbiology on p. 32-45

A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio

Bacteria require phase separation for fitness in the mammalian gut

Emilia Krypotou, Guy E. Townsend, Xiaohui Gao, Shoichi Tachiyama, Jun Liu, Nick D. Pokorzynski, Andrew L. Goodman, Eduardo A. Groisman, 2023, Science

Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity

Weiwei Han, Bee Zen Peng, Chunyan Wang, Guy E. Townsend, Natasha A. Barry, Frank Peske, Andrew L. Goodman, Jun Liu, Marina V. Rodnina, Eduardo A. Groisman, 2023, EMBO Journal

Erratum: A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor(mBio 11, 1, e03221-19, 2020, 10.1128/mBio.03221-19)

Guy E. Townsend, Weiwei Han, Nathan D. Schwalm, Xinyu Hong, Natasha A. Bencivenga-Barry, Andrew L. Goodman, Eduardo A. Groisman, 2020, mBio

Harnessing gut microbes for glycan detection and quantification

Jennifer L. Modesto, Victoria H. Pearce, Guy E. Townsend, 2023, Nature Communications

Dietary sugars silence the master regulator of carbohydrate utilization in human gut Bacteroides species

Victoria H. Pearce, Eduardo A. Groisman, Guy E. Townsend, 2023, Gut Microbes