Grayson Sipe

Assistant Professor of Biology

224 Huck Life Sciences
University Park, PA
gos5257@psu.edu

Bio & Links
Publications

Research Summary

Studying the molecular and cellular mechanisms that drive shifts in arousal, which are crucial for understanding maladaptive arousal in neuropsychiatric disorders such as anxiety and addiction.

Huck Affiliations

Neuroscience

Molecular, Cellular, and Integrative Biosciences

Center for Cellular Dynamics

Center for Molecular Investigation of Neurological Disorders

Neuroscience Institute

Center for Neurotechnology in Mental Health Research

Center for Brain, Behavior, and Cognition

Most Recent Publications

A paradigm for ethanol consumption in head-fixed mice during prefrontal cortical two-photon calcium imaging

Anagha Kalelkar, Grayson Sipe, Ana Raquel Castro E Costa, Ilka M. Lorenzo, My Nguyen, Ivan Linares-Garcia, Elena Vazey, Rafiq Huda, 2024, Neuropharmacology

Astrocyte glutamate uptake coordinates experience-dependent, eye-specific refinement in developing visual cortex

Grayson O. Sipe, Jeremy Petravicz, Rajeev V. Rikhye, Rodrigo Garcia, Nikolaos Mellios, Mriganka Sur, 2021, GLIA on p. 1723-1735

Distinct prefrontal top-down circuits differentially modulate sensorimotor behavior

Rafiq Huda, Grayson O. Sipe, Vincent Breton-Provencher, K. Guadalupe Cruz, Gerald N. Pho, Elie Adam, Liadan M. Gunter, Austin Sullins, Ian R. Wickersham, Mriganka Sur, 2020, Nature Communications

Author Correction: Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex (Nature Neuroscience, (2019), 22, 11, (1782-1792), 10.1038/s41593-019-0514-0)

Rianne D. Stowell, Grayson O. Sipe, Ryan P. Dawes, Hanna N. Batchelor, Katheryn A. Lordy, Brendan S. Whitelaw, Mark B. Stoessel, Jean M. Bidlack, Edward Brown, Mriganka Sur, Ania K. Majewska, 2020, Nature Neuroscience on p. 152

Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex

Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex

G. O. Sipe, R. L. Lowery, M. Tremblay, E. A. Kelly, C. E. Lamantia, A. K. Majewska, 2016, Nature Communications

Effects of Developmental Alcohol Exposure on Potentiation and Depression of Visual Cortex Responses

Crystal L. Lantz, Grayson O. Sipe, Elissa L. Wong, Ania K. Majewska, Alexandre E. Medina, 2015, Alcoholism: Clinical and Experimental Research on p. 1434-1442

Fluoxetine modulates breast cancer metastasis to the brain in a murine model

Yuriy Shapovalov, Martha Zettel, Sara C. Spielman, Stacy A. Amico-Ruvio, Emily A. Kelly, Grayson O. Sipe, Ian M. Dickerson, Ania K. Majewska, Edward B. Brown, 2014, BMC Cancer

Spectral sensitivity of the photointrinsic iris in the red-eared slider turtle (Trachemys scripta elegans)

Grayson O. Sipe, James R. Dearworth, Brian P. Selvarajah, Justin F. Blaum, Tory E. Littlefield, Deborah A. Fink, Corinne N. Casey, David H. McDougal, 2011, Vision Research on p. 120-130

Consensual pupillary light response in the red-eared slider turtle (Trachemys scripta elegans)

James R. Dearworth, Grayson O. Sipe, Lori J. Cooper, Erin E. Brune, Angela L. Boyd, Rhae A.L. Riegel, 2010, Vision Research on p. 598-605

Most-Cited Papers