Core Facilities News

Keep up with the latest news for Huck Core Facilities

Nora Margulis, left, and Anna Sigmon, right, after defending her thesis in Dec. 2022. Credit: Penn State. Creative Commons

January 25, 2024

Undergraduate research may contribute to COVID-19 treatments

Attending the 2023 Research Awards Ceremony hosted by Penn State’s College of Agricultural Sciences were, seated from left, Michael Skvarla, Kristina Brant, Timothy Lulis, Jasna Kovac, Margarita López-Uribe and Sridhar Komarneni. Standing: Tong Qiu, Parisa Kalantari, Andrew Patterson, Claudia Schmidt, Stephanie Bierly, Francesco Di Gioia, Zhang Tian, Jonathan Lynch and Suat Irmak. Credit: Kaiyi Chan / Penn State. Creative Commons

November 21, 2023

College of Ag Sciences recognizes faculty, staff for research achievements

Research Professor Cheryl Keller gestures to an Illumina NextSeq2000 DNA sequencer while speaking with research technologist Huiqing Zeng. Credit: Keith Hickey / Penn State. Creative Commons

October 30, 2023

Genomics Research Incubator expands assay and training options for scientists

Katsuhiko Murakami, professor of biochemistry and molecular biology. Credit: Michelle Bixby / Penn State. Creative Commons

October 24, 2023

Biochemist selected as Innovation Fund investigator by Pew Charitable Trusts

New images of the SIRT6 sirtuin enzyme — which regulates aging and other metabolic processes — help explain how it is able to access genetic material within the cell. This cryo-electron microscopy map shows the enzyme in complex with the nucleosome, a tightly packed complex of DNA and proteins called histones. Credit: Song Tan lab / Penn State. All Rights Reserved.

April 14, 2023

How does an aging-associated enzyme access our genetic material?

Researchers have worked out the mechanism of transcription pausing in some bacteria by determining the structures of RNA polymerase in a complex with a DNA template, an RNA product, and a protein factor using cryo-electron microscopy (cryo-EM). The nucleotide addition cycle of bacterial RNA polymerase (RNAP) is depicted by cartoon models of template DNA (tDNA, green), RNA (red), trigger loop (TL, magenta), bridge helix (BH, blue), incoming NTP (red) and Mg2+ (yellow spheres) together with the conformational changes of RNAP (swiveling, folding Trigger loop) associated with each step of the nucleotide addition cycle. NusG and non-template DNA (ntDNA, light green) interaction (center panel) inhibits the RNAP swiveling, the Trigger loop folding allosterically thus pauses RNA synthesis. Credit: Murakami Laboratory / Penn State. Creative Commons

February 09, 2023

DNA stuck in the gears of the RNA production machine

Andrew Patterson and Jonathan Lynch in Penn State’s College of Agricultural Sciences were recognized recently as highly cited researchers. Credit: Penn State. Creative Commons

January 12, 2023

Two College of Ag Sciences faculty among highly cited researchers in 2022

Several types of techniques are utilized at Penn State’s Flow Cytometry Facility to analyze various parts and processes of cells, according to Mani. Some of these techniques include, immunophenotyping, cell cycle/DNA ploidy analysis, apoptosis assays, imaging flow cytometry, and cell sorting. Credit: iStock. All Rights Reserved.

November 02, 2022

Flow Cytometry Core Facility provides cell analysis expertise to scientists

Metabolomics researchers.

September 02, 2022

Metabolomics Core Facility continues to expand while pushing scientific bounds

Greg Ning portrait.

February 25, 2022

Microscopy director propagates new discoveries and new scientists

Neela Yennawar, director of the X-Ray Crystallography and the Automated Biological Calorimetry, Penn State Huck Institutes of the Life Sciences. Credit: Penn State. Creative Commons

January 13, 2022

Core facilities director brings more than technical advice to research

Leadership teams from Gamma Biosciences and BioMagnetic Solutions visit Penn State, November 2021

December 14, 2021

Biotech company selects Innovation Park for expansion

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