136 People Results for the Tag: Phenotype

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John Carlson

Professor of Molecular Genetics; Director, Schatz Center for Tree Molecular Genetics
Genome mapping, including genetic linkage mapping, molecular cytogenetics; studies of genetic diversity in forests.

Laura Carrel

Associate Professor of Biochemistry and Molecular Biology
Chromosome structure and function Genome organization Long-range control of gene expression Heterochromatin formation Epigenetic role in human disease Genetics and genomics of X chromosome inactivation in human and mouse

Surinder Chopra

Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.

Darrell Cockburn

Assistant Professor of Food Science

Isabella Cattadori

Associate Professor of Biology
Immuno-epidemiology of co-infection, how host immunity modulates parasite interactions and transmission and how host molecular processes explain the dynamics of infection at the population level.

Center for Infectious Disease Dynamics

Santhosh Girirajan

Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
Understanding the genetic basis of neurodevelopmental disorders.

Adam Glick

Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Molly Hall

Assistant Professor of Veterinary and Biomedical Sciences
Building tools to elucidate the complex genetic and environmental underpinnings of human disease. Integrating genetic (genotype, sequence, structural variation) and exposure (derived from surveys and metabolomics methods) big data to predict disease status.

Wendy Hanna-Rose

Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans

Heather Hines

Associate Professor of Biology and Entomology
Genetics of adaptive mimetic color pattern variation in butterflies and bumble bees

Kevin Hockett

Assistant Professor of Microbial Ecology, Department of Plant Pathology and Environmental Microbiology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty

Center for Infectious Disease Dynamics

Timothy Jegla

Emphasis Area Representative, Molecular and Evolutionary Genetics; Associate Professor of Biology
Functional evolution of eukaryotic ion channels and evolution of neuronal signaling and cell structure.

Joyce Jose

Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.

Center for Infectious Disease Dynamics

Aimin Liu

Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.

Sally Mackenzie

Lloyd and Dottie Huck Chair for Functional Genomics; Professor of Biology; Professor of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.

Timothy McNellis

Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.

Robert Paulson

Professor of Veterinary and Biomedical Sciences
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress

George Perry

Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Anthropology and Biology
Anthropological genomics, paleogenomics, human body size evolution, parasite evolution, and evolutionary medicine.

Center for Infectious Disease Dynamics

Jeffrey Peters

Distinguished Professor of Molecular Toxicology and Carcinogenesis
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.

Kathleen Postle

Professor of Biochemistry and Molecular Biology
Signal transduction and iron transport in bacteria

Jason Rasgon

Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.

Center for Infectious Disease Dynamics

Melissa Rolls

Chair, Intercollege Graduate Degree Program in Molecular, Cellular and Integrative Biosciences; Director of the Center for Cellular Dynamics; Professor of Biochemistry and Molecular Biology
Subcellular compartmentalization of neurons. The cellular basis of neuronal polarity and neuronal responses to injury including degeneration and regeneration.

Troy Sutton

Assistant Professor of Veterinary and Biomedical Sciences
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research

Center for Infectious Disease Dynamics

David Vandenbergh

Professor of Biobehavioral Health
Genetics of addiction in human populations and its neurobiological basis in animal models.

Thomas K Wood

Endowed Chair Professor of Engineering

Na Xiong

Associate Professor, Department of Veterinary and Biomedical Science
Development and function of gamma/delta T cells, a class of immune cells with various roles in microbial immunity, inflammation regulation and tumor surveillance.

Yinong Yang

Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.

Edward Dudley

Professor of Food Science; Director of E. coli Reference Center
Mechanisms driving toxin production in Shiga-toxigenic Escherichia coli; use of genome sequencing to track pathogen transmission during foodborne outbreaks

Center for Infectious Disease Dynamics

James Marden

Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.

Center for Infectious Disease Dynamics

Jasna Kovac

Lester Earl and Veronica Casida Career Development Professor of Food Safety; Assistant Professor of Food Science
Integrating epidemiological, microbiological, molecular and omics methods to better understand microbial pathogenic potential, antimicrobial resistance, and epidemiology of foodborne pathogens.

Center for Infectious Disease Dynamics

Jesse Lasky

Assistant Professor of Biology
Ecological and evolutionary genomics, genetic and ecophysiological basis of adaptation to environmental stress, evolutionary ecology of biological complexity.

Center for Infectious Disease Dynamics

Mary Kennett

Professor, Veterinary & Biomedical Sciences; Director, Animal Resource Program
The pathogenesis of infectious disease: examining bacterial virulence and associated pathology in relation to host immune responses.

Center for Infectious Disease Dynamics

Moriah Szpara

Associate Professor of Biochemistry & Molecular Biology
Neurovirology, genomics of pathogen variation, neuron-virus relationships

Center for Infectious Disease Dynamics

Alison Gernand

Ann Atherton Hertzler Early Career Professor in Global Health; Assistant Professor of Nutritional Sciences

Andrew Deans

Professor of Entomology, Director of the Frost Entomological Museum

Bernhard Luscher

Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action

Carolee Bull

Director of the Microbiome Center; Professor of Plant Pathology; Bacterial Systematics Head, Department of Plant Pathology and Environmental Microbiology
Bacterial systematics, epidemiology, and population biology of bacterial plant pathogens and biological control agents to develop alternatives to synthetic chemicals for plant disease management

Cristina Rosa

Assistant Professor of Plant Pathology & Environmental Microbiology
Plant Virology, interaction of plant viruses with their insects as vectors and with their plant hosts. Virus evolution, exploration of plant viromes, viral co-infections, effect of climate change on viral resistant breaking strains. Use of nanotechnologies for virus detection and virus disease management.

Dajiang Liu

Associate Professor of Public Health Science
Developing novel methods to analyze very large scale datasets in order to identify genes that are responsible for disease, understand the disease mechanism, and gain clinical insights.

Douglas Cavener

Professor and Verne M. Willaman Dean, Eberly College of Science; Chair of the Genetics Program
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Francisco Diaz

Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Gary Felton

Professor and Department Head of Entomology
Plant-herbivore interactions. Adaptive responses of herbivores to plant defenses. Herbivore cues recognized by plants with specific focus on biochemical and molecular analysis of salivary secretions.

Helen Kamens

Assistant Professor of Biobehavioral Health
Identification of genetic mechanisms that contribute to complex behaviors with a special emphasis on alcohol and tobacco use.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Joy Pate

Director of the Center for Reproductive Biology and Health; Professor of Reproductive Physiology; C. Lee Rumberger and Family Chair in Agricultural Sciences
Specializing in the area of corpus luteum function. Primary research interests focus on the regulation of luteolysis, prostaglandin production by the corpus luteum, and the interactions between the immune system & the reproductive system.

Kelli Hoover

Professor of Entomology
Invasive species of forest insects; plant-insect-entomopathogen interactions; impacts of plants on pathogenesis; biological control of hemlock woolly adelgid

Matthew Reimherr

Associate Professor of Statistics

Pamela Giblin

Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Richard Ordway

Professor of Molecular Neuroscience and Genetics
Genetic analysis of neural function.

Ross Hardison

Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.

Rudolf Schilder

Assistant Professor of Entomology and Biology
Comparative & ecological physiology of insect and mammalian locomotion.

Scott Selleck

Professor of Biochemistry and Molecular Biology

Troy Ott

Associate Director for Graduate Education, Huck Institutes of the Life Sciences; Professor of Reproductive Physiology
Reproductive immunology and the physiology of early pregnancy.

Zhi-Chun Lai

Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

Gary Clawson

Professor of Pathology, Biochemistry and Molecular Biology

Kristin Eckert

Professor of Pathology and Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.

Gary Perdew

Director of the Center for Molecular Toxicology and Carcinogenesis; John T. and Paige S. Smith Professor in Agricultural Sciences
Mechanisms of receptor-mediated carcinogenesis.

Kathleen Brown

Professor of Plant Stress Biology
Regulation of root development. Root responses to edaphic stress. Identification and genetic mapping of traits for adaptation to edaphic stress.

Wayne Curtis

Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.

Mark Guiltinan

J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.

Jonathan Lynch

Distinguished Professor of Plant Nutrition
Plant adaptation to nutrient and water stress. Global change. World hunger. Root biology.

Sarah Bronson

Associate Professor of Cellular and Molecular Physiology

Neil Christensen

Professor of Pathology and Microbiology and Immunology

Keith Cheng

Distinguished Professor of Pathology; Professor of Biochemistry & Molecular Biology; Professor of Pharmacology

Jan McAllister

Professor of Cellular and Molecular Physiology

David Huff

Professor of Turfgrass Breeding and Genetics
Population genetics. Plant evolution and ecology. Crop improvement. Physiological tolerance to biotic and abiotic stress.

Seogchan Kang

Professor of Plant Pathology & Environmental Microbiology
Genetic and cellular mechanisms underpinning plant-fungal interactions with Arabidopsis thaliana and Fusarium oxysporum as a model system. Molecular genetics and comparative genomics of fungal plant pathogens. Bioinformatics.

Ralph Keil

Associate Professor of Biochemistry and Molecular Biology

Joan Richtsmeier

Professsor of Anthropology
Analysis of craniofacial phenotypes.

Todd Schell

Professor Microbiology & Immunology

James Wang

Professor of Information Science and Technology
Modeling of objects, concepts, aesthetics, and emotions in big visual data from various domains.

Colin Barnstable

Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

Kumble Sandeep Prabhu

Professor of Immunology and Molecular Toxicology
Molecular mechanisms by which bioactives such as selenium, omega-3 fatty acids, and other products of natural origin alter the host response and immune function in inflammation and cancer

John Wills

Distinguished Professor of Microbiology and Immunology

Fumiko Kawasaki

Associate Research Professor
Genetic and Molecular Studies of Neural Function and Degeneration

James Adair

Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations

Joshua Lambert

Associate Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals

Rongling Wu

Director of the Center for Statistical Genetics; Professor of Public Health Sciences

Ying Gu

Associate Professor, Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

Gabriele Monshausen

Associate Professor of Biology
Plant cell signaling. Hormonal and mechanical signal transduction in plant growth regulation. Live cell imaging of subcellular microdomains of ionic signaling.

Charles Anderson

Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.

James Broach

Professor and Chair, Biochemistry and Molecular Biology

Kathryn Suzanne Scherf

Associate Professor of Psychology
Development of face and object representation in typically developing children and children with developmental disorders.

Greg Shearer

Associate Professor of Nutritional Sciences
We seek to understand disease-related functional changes in the context of global changes in lipid mediators (bioactive metabolites of dietary fatty acids) and use them to identify markers of disease and better ways to prevent or manage disease

Erin Connolly

Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis

Xiaojun Lian

Assistant Professor of Biomedical Engineering
Human Stem Cell Engineering; Genome Editing via CRISPR-Cas9; Epigenome Editing and Epigenetics.

Scott Medina

Assistant Professor of Biomedical Engineering
Design of bio-inspired functional materials that serve as new tools in precision medicine. Understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. The design of nano- and micro-scale biomaterials to develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer.

Nigel Deighton

Director of Research Instrumentation
Oversight of Huck facility operations, strategic direction and leadership in programmatic growth, and grant opportunities

Suzanne Gonzalez

Assistant Professor of Psychiatry
My laboratory focuses on neuropsychiatric genetics in diverse populations. I am particularly interested in understanding how genetic polymorphisms within key physiological pathways translate into clinical phenotypes of psychiatric disorders, such as bipolar disease and schizophrenia.

Xiang Zhan

Assistant Professor of Public Health Sciences

Joseph Cotruvo

Assistant Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.

Gretchen Kuldau

Associate Professor of Plant Pathology

Aron Lukacher

Professor and Chair of Microbiology & Immunology

Mauricio Pontes

Assistant Professor of Pathology

Kari Peter

Assistant Research Professor of Tree Fruit Pathology

Tami Mysliwiec

Associate Professor of Biology

Justin DiAngelo

Assistant Professor of Biochemistry and Molecular Biology

Gary Thompson

Associate Dean for Research and Graduate Education, College of Agricultural Sciences; Director, PA Agricultural Experiment Station

María del Mar Jiménez Gasco

Associate Professor of Plant Pathology and Environmental Mictobiology

Howard Fescemyer

Assistant Research Professor

Sung Hyun Cho

Assistant Research Professor, Cryo-Electron Microscopy Core Facility

Sarah E Nilson

Assistant Professor of Biology - PSU Beaver

Hojae Yi

Assistant Research Professor of Agricultural and Biological Engineering