175 People Results for the Tag: Phenotype

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Istvan Albert

Research Professor of Bioinformatics
Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.

Center for Infectious Disease Dynamics

Reka Albert

Distinguished Professor of Physics and Biology
Biological physics and network modeling.

Center for Infectious Disease Dynamics

Michael Axtell

Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets

Laura Carrel

Associate Professor of Biochemistry and Molecular Biology
Genetic, epigenetic, and genomic regulation of expression on the mammalian X chromosome.

Sonia Cavigelli

Associate Professor of Biobehavioral Health
Development of temperament/personality; relationship of temperament and social status to stress and health; individual differences in stress and health in the natural environment.

Surinder Chopra

Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.

Isabella Cattadori

Associate Professor of Biology
Immuno-epidemiology of co-infection, how host immunity modulates parasite interactions and transmission and how host molecular processes explain the dynamics of infection at the population level.

Center for Infectious Disease Dynamics

Santhosh Girirajan

Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
Understanding the genetic basis of neurodevelopmental disorders.

Adam Glick

Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Molly Hall

Dr. Frances Keesler Graham Early Career Professor; Assistant Professor of Veterinary and Biomedical Sciences
Building tools to elucidate the complex genetic and environmental underpinnings of human disease. Integrating genetic (genotype, sequence, structural variation) and exposure (derived from surveys and metabolomics methods) big data to predict disease status.

Wendy Hanna-Rose

Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans

Heather Hines

Associate Professor of Biology and Entomology
Applies genomic, transcriptomic, phylogenomic, and bioinformatic approaches to study the evolution and genetics of diverse traits in bees and wasps. This includes study of mimetic color diversification, plant gall induction, novel morphologies, speciation, and social evolution.

Kevin Hockett

Huck Early Career Chair; Assistant Professor of Microbial Ecology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty

Center for Infectious Disease Dynamics

Timothy Jegla

Emphasis Area Representative, Molecular and Evolutionary Genetics; Associate Professor of Biology
Functional evolution of eukaryotic ion channels and evolution of neuronal signaling and cell structure.

Kenneth Keiler

Professor of Biochemistry and Molecular Biology
Small RNAs and protein localization in bacterial development and antimicrobial drug discovery.

Girish Kirimanjeswara

Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors

Center for Infectious Disease Dynamics

Manuel Llinas

Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.

Center for Infectious Disease Dynamics

Hong Ma

Huck Distinguished Research Professor of Plant Molecular Biology; Professor of Biology
Plant development under favorable and stressful conditions; phylogeny and evolutionary biology of plant groups containing major crops and ecologically important species.

Sally Mackenzie

Huck Chair of Functional Genomics; Professor of Biology; Professor of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.

Yingwei Mao

Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Elizabeth McGraw

Professor and Huck Scholar in Entomology
The genetics of vector, pathogen and symbiont interactions.

Center for Infectious Disease Dynamics

Timothy McNellis

Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.

Robert Paulson

Professor of Veterinary and Biomedical Sciences
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress

Kathleen Postle

Professor of Biochemistry and Molecular Biology
Signal transduction and iron transport in bacteria

Jason Rasgon

Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.

Center for Infectious Disease Dynamics

Philip Smith

Director, Metabolomics Core Facility; Associate Research Professor, Proteomics and Mass Spectrometry Core Facility (University Park)

David Toews

Assistant Professor of Biology

David Vandenbergh

Professor of Biobehavioral Health
Genetics of addiction in human populations and its neurobiological basis in animal models.

Thomas K Wood

Endowed Chair Professor of Engineering

Yinong Yang

Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.

Nanyin Zhang

Huck Chair in Brain Imaging; Professor of Bioengineering
Investigate the pathophysiology of brain disorders using neuroimaging, behavioral and optogenetic methods.

Ephraim M. Hanks

Associate Professor of Statistics
Spatio-Temporal Statistics. Bayesian Hierarchical Modeling. Optimal Sampling. Animal Movement. Landscape Genetics.

Center for Infectious Disease Dynamics

James Marden

Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.

Center for Infectious Disease Dynamics

Jasna Kovac

Lester Earl and Veronica Casida Career Development Professor of Food Safety; Assistant Professor of Food Science
Integrating epidemiological, microbiological, molecular and omics methods to better understand microbial pathogenic potential, antimicrobial resistance, and epidemiology of foodborne pathogens.

Center for Infectious Disease Dynamics

Jesse Lasky

Assistant Professor of Biology
Ecological and evolutionary genomics, genetic and ecophysiological basis of adaptation to environmental stress, evolutionary ecology of biological complexity.

Center for Infectious Disease Dynamics

Moriah Szpara

Associate Professor of Biochemistry & Molecular Biology and Biology
How genetic variation influences the outcomes of viral infection, particularly for neurotropic viruses such as herpes simplex virus 1 (HSV-1) and HSV-2, using high-throughput sequencing, comparative genomics, neuronal cultures, and genetic manipulation of both host and pathogen.

Center for Infectious Disease Dynamics

Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Center for Infectious Disease Dynamics

Andrew Deans

Professor of Entomology, Director of the Frost Entomological Museum

Bernhard Luscher

Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action

Catharine Ross

Professor in Nutritional Science; Dorothy Foehr Huck Chair
Vitamin A metabolism; hepatic retinoid function and gene expression; vitamin A in infection and immunity.

Connie Rogers

Associate Director, Huck Institutes of the Life Sciences; Associate Professor of Nutritional Sciences
Role of changes in energy balance and related nutritional factors on inflammation, immune regulation, and cancer risk using both animal models and human subjects.

Cristina Rosa

Associate Professor of Plant Pathology & Environmental Microbiology
Plant Virology, interaction of plant viruses with their insects as vectors and with their plant hosts. Virus evolution, exploration of plant viromes, viral co-infections, effect of climate change on viral resistant breaking strains. Use of nanotechnologies for virus detection and virus disease management.

Dajiang Liu

Associate Professor of Public Health Science
Developing novel methods to analyze very large scale datasets in order to identify genes that are responsible for disease, understand the disease mechanism, and gain clinical insights.

Douglas Cavener

Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Edwin Rajotte

Professor of Entomology and IPM Coordinator

Fang (Rose) Zhu

Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.

Francisco Diaz

Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Helen Kamens

Assistant Professor of Biobehavioral Health
Identification of genetic mechanisms that contribute to complex behaviors with a special emphasis on alcohol and tobacco use.

Howard Salis

Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.

Kateryna Makova

Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.

Kory Blose

Assistant Research Professor

Pamela Giblin

Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Paul Bartell

Chair, Intercollege Graduate Degree Program in Neuroscience; Associate Professor of Avian Biology
The regulation of biological clocks in birds at the systems level.

Ross Hardison

Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.

Rudolf Schilder

Associate Professor of Entomology and Biology
Comparative & ecological physiology of insect and mammalian locomotion.

Scott Selleck

Professor of Biochemistry and Molecular Biology

Wansheng Liu

Professor of Genomics
Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.

Robab Katani

Assistant Research Professor of Global Health
Global health security, infectious diseases, and host-pathogen dynamics, as well as expertise in the enhancement of capabilities in the Low- and Middle-Income Countries, including Tanzania and India.

Center for Infectious Disease Dynamics

Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

Sally Assmann

Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.

Zhi-Chun Lai

Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics

Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

Kristin Eckert

Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.

Donald Bryant

Ernest C. Pollard Professor of Biotechnology; Professor of Biochemistry and Molecular Biology
Photosynthesis, structure-function relationships of proteins, gene regulation, and microbial physiology. Cyanobacteria and green sulfur bacteria. Genomics of photosynthetic bacteria.

Ming Tien

Professor of Biochemistry & Molecular Biology
Characterization and biochemical analysis of cellulose synthesis in a variety of organisms. Mechanism and regulation of fungal degradation of lignin. Dissimilatory Iron reduction.

Kathleen Brown

Professor of Plant Stress Biology
Regulation of root development. Root responses to edaphic stress. Identification and genetic mapping of traits for adaptation to edaphic stress.

Wayne Curtis

Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.

Jonathan Lynch

Director of the Center for Root and Rhizosphere Biology; Distinguished Professor of Plant Nutrition
Plant adaptation to nutrient and water stress. Global change. World hunger. Root biology.

Sarah Bronson

Associate Professor of Cellular and Molecular Physiology

Timothy Craig

Professor of Medicine and Pediatrics in the Department of Medicine, Section of Pulmonary, Allergy and Critical Care

Keith Cheng

Distinguished Professor of Pathology and Laboratory Medicine, of Biochemistry and Molecular Biology, and of Pharmacology
Computational phenomics, image informatics, and "Geometry of Life" based on x-ray histotomography, population, genomic, and functional genomic analyses of complex traits in human and zebrafish; web-based science resources.

Jan McAllister

Professor of Cellular and Molecular Physiology

Mark Shriver

Professor of Biological Anthropology
Human population genomics and complex disease mapping.

David Huff

Professor of Turfgrass Breeding and Genetics
Population genetics. Plant evolution and ecology. Crop improvement. Physiological tolerance to biotic and abiotic stress.

David Geiser

Professor of Mycology
Molecular evolutionary genetics of pathogenic and toxigenic fungi.

Ralph Keil

Associate Professor of Biochemistry and Molecular Biology

Pamela Mitchell

Emeritus Associate Professor of Biology

Joan Richtsmeier

Professsor of Anthropology
Analysis of craniofacial phenotypes.

Diane Thiboutot

Professor of Medicine and Dermatology

Gavin Robertson

Professor of Pharmacology

Peter Butler

Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.

Todd Schell

Professor Microbiology & Immunology

Shantu Amin

Professor of Pharmacology

Dhimant Desai

Associate Professor of Pharmacology

Arun Sharma

Associate Professor of Pharmacology

Colin Barnstable

Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

Kumble Sandeep Prabhu

Professor of Immunology and Molecular Toxicology
Molecular mechanisms by which bioactives such as selenium, omega-3 fatty acids, and other products of natural origin alter the host response and immune function in inflammation and cancer

John Wills

Distinguished Professor of Microbiology and Immunology

Fumiko Kawasaki

Associate Research Professor
Genetic and Molecular Studies of Neural Function and Degeneration

Tomas Carlo-Joglar

Associate Professor of Biology

Gabriele Monshausen

Associate Professor of Biology
Plant cell signaling. Hormonal and mechanical signal transduction in plant growth regulation. Live cell imaging of subcellular microdomains of ionic signaling.

Charles Anderson

Co-Director, Center for Biorenewables; Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.

David Miller

Associate Professor of Wildlife Population Ecology
Population ecology, quantitative ecology, avian and amphibian ecology, conservation decision analysis, life-history evolution.

Sinisa Dovat

Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.

Kathryn Suzanne Scherf

Associate Professor of Psychology
Development of face and object representation in typically developing children and children with developmental disorders.

Chris Engeland

Assistant Professor of Biobehavioral Health and Nursing
How stress, age, gender, and hormones affect inflammation / health. Biomarker feasibility for predicting health outcomes.

Tim Miyashiro

Assistant Professor of Biochemistry and Molecular Biology
How bacteria adapt to a host environment. The mutualistic symbiosis established between the Hawaiian bobtail squid (Euprymna scolopes) and a bioluminescent bacterium (Vibrio fischeri).

Center for Infectious Disease Dynamics

Justin Brown

Associate Professor of Bioengineering
Understanding the fundamental mechanisms by which biomaterial interfaces alter the proliferation, migration and differentiation of mesenchymal stem cells, and application of these principles in the intelligent design of biomaterial scaffolds that facilitate generation or regeneration of musculoskeletal tissues

Reuben Kraft

Shuman Assistant Professor of Mechanical Engineering
Computational methods and high performance computing to examine brain neurotrauma biomechanics; human structural connectome analysis using physics-based predictions of biomechanical brain injury.

Edward O’Brien

Associate Professor of Chemistry
Developing and applying Physical Bioinformatic techniques to measure rates of translation transcriptome-wide and their molecular origins as relates to fundamental biology and disease.

Gustavo Nader

Associate Professor of Kinesiology
Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.

Erin Connolly

Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis

Scott Medina

Assistant Professor of Biomedical Engineering
Design of bio-inspired functional materials that serve as new tools in precision medicine. Understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. The design of nano- and micro-scale biomaterials to develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer.

Thomas Gould

Jean Phillips Shibley Professor and Department Head of Biobehavioral Health
Using genetic, pharmacological, behavioral, and molecular biological techniques to study the neurobiology of learning and memory and the effects of addiction on it.

Tatiana Laremore

Director, Proteomics and Mass Spectrometry Core Facility

Thomas Neuberger

Director, High Field Magnetic Resonance Imaging Facility

Nigel Deighton

Director of Research Instrumentation
Oversight of Huck facility operations, strategic direction and leadership in programmatic growth, and grant opportunities

Andrew Patterson

Professor and Huck Chair of Molecular Toxicology; Faculty Oversight, Metabolomics Core Facility
The Patterson lab is focused on understanding the host-metabolite-microbiome axis

Runze Li

Co-Director of the Center for Statistical Genetics; Eberly Family Chair and Associate Department Head in Statistics

Nikolay Dokholyan

G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.

Center for Infectious Disease Dynamics

Suzanne Gonzalez

Assistant Professor of Psychiatry and Behavioral Health and of Pharmacology
My laboratory focuses on neuropsychiatric genetics in diverse populations. I am particularly interested in understanding how genetic polymorphisms within key physiological pathways translate into clinical phenotypes of psychiatric disorders, such as bipolar disease and schizophrenia.

Elizabeth Proctor

Assistant Professor of Neurosurgery, Pharmacology, Biomedical Engineering, and Engineering Science & Mechanics
Systems biology of complex disease. Integration of heterogeneous data types across length scales.

Xiang Zhan

Assistant Professor of Public Health Sciences

Yasser El-Manzalawy

Assistant Research Professor of Information Sciences and Technology

Pia Abel zur Wiesch

Huck Early Career Chair in Systems Pharmacology; Associate Professor of Biology

Center for Infectious Disease Dynamics

Yifei Huang

Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.

Timothy Meredith

Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.

Nikki Crowley

Assistant Professor of Biology
investigation of peptidergic transmission throughout the brain, using cell-specific and pathway-specific manipulations to understand how peptides alter neuronal signaling and behavior, particularly in the context of stress and drug use.

Raymond Hohl

University Professor of Oncology; Professor of Pharmacology

Gretchen Kuldau

Associate Professor of Plant Pathology

Aron Lukacher

Professor and Chair of Microbiology & Immunology

Mauricio Pontes

Assistant Professor of Pathology

Kari Peter

Assistant Research Professor of Tree Fruit Pathology

Thomas Ma

Professor and Chair of Medicine

Justin DiAngelo

Assistant Professor of Biochemistry and Molecular Biology

Josephine Wee

Assistant Professor of Food Science

Gary Thompson

Associate Dean for Research and Graduate Education, College of Agricultural Sciences; Director, PA Agricultural Experiment Station

Emily Weinert

Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Emily Davenport

Assistant Professor of Biology
Understanding the complex relationship humans have with our microbiomes, using high-throughput sequencing technologies and novel computational and statistical techniques.

Sung Hyun Cho

Assistant Research Professor, Cryo-Electron Microscopy Core Facility

Luis Duque

Assistant Research Professor of Storage Root Physiology

Ruairidh Sawers

Assistant Professor of Plant Response to Abiotic Stress
Local adaptation and stress tolerance in crop plants and their wild relatives; plant nutrition; arbuscular mycorrhizae; maize genetics and genomics.

Ibrahim Ozbolat

Hartz Family Associate Professor of Engineering Science and Mechanics

Liana Burghardt

Assistant Professor; Huck Early Career Chair of Root Biology and Rhizosphere Interactions
Plant-microbe-climate interactions; the evolution and ecology of legumes and nitrogen-fixing rhizobia; the genomic basis and environment dependence of root, nodule, and mutualism traits; GWAS/transcriptomics/evolve & resequence methodologies

William Driscoll

Assistant Professor of Biology

Spencer Szczesny

Assistant Professor of Bioengineering

Virendra Puri

Distinguished Professor of Agricultural and Biological Engineering Powder Mechanics and Food Processing

Zachary Szpiech

Assistant Professor of Biology
Population and evolutionary genetics, with applications to medical genetics, anthropology, and conservation

Xiang Zhu

Assistant Professor of Statistics
Statistical Genetics and Genomics

Jason Keagy

Assistant Research Professor of Wildlife Behavioral Ecology
Cognitive ecology (with studies at genome, individual, and species levels). I am particularly interested in applications for solving wildlife management problems

Lindsay Fernandez-Rhodes

Assistant Professor of Biobehavioral Health
The genetic epidemiology of complex diseases in diverse human populations and contexts.