45 People Results for the Tag: Down Regulation
Istvan Albert
Research Professor of Bioinformatics
Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.
Center for Infectious Disease Dynamics
Margherita Cantorna
Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.
Center for Infectious Disease Dynamics
Sonia Cavigelli
Chair, Intercollege Graduate Degree Program in Neuroscience; Associate Professor of Biobehavioral Health
Development of temperament/personality; relationship of temperament and social status to stress and health; individual differences in stress and health in the natural environment.
Adam Glick
Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.
Center for Infectious Disease Dynamics
Girish Kirimanjeswara
Emphasis Area Representative, Immunology and Infectious Disease; Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors
Center for Infectious Disease Dynamics
Qunhua Li
Associate Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Statistics
Developing statistical and computational methods for analyzing complex omics data and improving quality and reproducibility of high-throughout data
Catharine Ross
Professor in Nutritional Science; Dorothy Foehr Huck Chair
Vitamin A metabolism; hepatic retinoid function and gene expression; vitamin A in infection and immunity.
Fang (Rose) Zhu
Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.
Helen Kamens
Assistant Professor of Biobehavioral Health
Identification of genetic mechanisms that contribute to complex behaviors with a special emphasis on alcohol and tobacco use.
Ramesh Ramachandran
Professor of Molecular Endocrinology
The influence of hypothalamic neurotransmitters, hormones, and their receptors on avian reproduction.
Ross Hardison
Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.
Scott Showalter
Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.
Shaun Mahony
Associate Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity
Claire Thomas
Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.
Ming Tien
Professor of Biochemistry & Molecular Biology
Characterization and biochemical analysis of cellulose synthesis in a variety of organisms. Mechanism and regulation of fungal degradation of lignin. Dissimilatory Iron reduction.
Colin Barnstable
Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.
Kumble Sandeep Prabhu
Professor of Immunology and Molecular Toxicology
Molecular mechanisms by which bioactives such as selenium, omega-3 fatty acids, and other products of natural origin alter the host response and immune function in inflammation and cancer
Sinisa Dovat
Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.
Yong Wang
Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.
Center for Infectious Disease Dynamics
Justin DiAngelo
Assistant Professor of Biochemistry and Molecular Biology
Tae Hyun Kim
Huck Early Career Chair; Assistant Professor of Avian Biology
Improving poultry health by applying modern genetic approaches including gene editing. Particular focus on identifying key genes and regulatory elements associated with improved economic traits.
Center for Infectious Disease Dynamics
Yuguo (Leo) Lei
Associate Professor of Biomedical Engineering; Faculty Oversight, Sartorius Cell Culture Facility
Cell therapy; Cell manufacturing; Biomaterials
Parisa Kalantari
Assistant Professor of Immunology
Host-parasite interactions using Schistosoma mansoni-induced liver inflammation in mouse models. Modulation of immune responses by the parasite as well as the role of inflammasomes in inducing schistosomiasis.
Yasin Uzun
Assistant Professor of Pediatrics
Developing and
applying systems biology approaches to better understand gene regulation at the
molecular level in development and disease by using single-cell genomic
sequencing data.
Lynne Beaty
Assistant Professor of Biology, Penn State Behrend
Behavioral ecology with a particular emphasis on the role of previous experience with predation risk on the phenotype of prey; anurans, freshwater biology, latent/carry-over effects, phenotypic plasticity