Advances In Cryo-EM Materials May Aid Cancer And Biomedical Research

Cryogenic-Electron Microscopy (cryo-EM) has been a game changer in the field of medical research, but the substrate used to freeze and view samples under a microscope hasn’t advanced much in decades. Now, thanks to a collaboration between Penn State researchers and the applied science company Protochips, Inc., this is no longer the case.

Deb Kelly’s research team in the department of biomedical engineering and the Center for Structural Oncology at Penn State is developing a new Cryo-EM-On-a-Chip approach. This new technology permits researchers to see the genetic faults within the depths of cancer cells, including those from the brain. Illustration credit: Daryl Branford and Deb Kelly/Penn State
Deb Kelly’s research team in the department of biomedical engineering and the Center for Structural Oncology at Penn State is developing a new Cryo-EM-On-a-Chip approach. This new technology permits researchers to see the genetic faults within the depths of cancer cells, including those from the brain. Illustration credit: Daryl Branford and Deb Kelly/Penn State