Associate Professor of Bioinformatics
Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.
Huck Early Career Professor; Assistant Professor of Biology
The underlying mechanisms for spatial heterogeneities in host disease burden and risk across spatial scales, from regional dynamics to seasonal outbreaks in cities, rural villages, and across borders by assessing regional variations in movement and contact patterns relating to outbreaks and access to health care.
Huck Chair of Epidemiology; Distinguished Professor of Entomology and Biology; Adjunct Professor in Statistics
Population ecology and population dynamics with particular emphasis on mathematical and computational aspects
Associate Professor of Biology
Human influenza epidemiology and evolution, evaluating population-level malaria treatment strategies with individual-based microsimulation models, phylogenetic analysis of avian influenza evolution in southern Vietnam, economic epidemiology of avian influenza, evaluating population-level efficacy of a potential dengue vaccine with mathematical models
Emphasis Area Representative, Immunology and Infectious Disease; Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.
Associate Professor of Biology
Immuno-epidemiology of co-infection, how host immunity modulates parasite interactions and transmission and how host molecular processes explain the dynamics of infection at the population level.
Assistant Professor of Plant Science
Microbiome, plant-microbe interactions, and community ecology. Harnessing the plant microbiome to enhance protection against biotic and abiotic stresses.
G. Thomas Passananti Professor
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.
Professor of Food Science; Director of E. coli Reference Center
Mechanisms driving toxin production in Shiga-toxigenic Escherichia coli; use of genome sequencing to track pathogen transmission during foodborne outbreaks
Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.
Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.
Associate Professor of Statistics
Statistical computing (Markov chain Monte Carlo algorithms); spatial models (Gaussian random field models); methods for complex computer models; interdisciplinary collaborations in environmental sciences, climate science, disease modeling, ecology
Huck Early Career Chair; Assistant Professor of Microbial Ecology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty
Former Director, Huck Institutes of the Life Sciences; Willaman Professor of Biology
Population dynamics of infectious diseases in wildlife and the dynamics of parasite community structure.
Professor of Statistics, Department Head
I work on statistical models for networks, mixture models, and certain optimization algorithms called MM algorithms. A full list of papers and related work, such as software, may be found at http://sites.stat.psu.edu/~dhunter/.
Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.
Associate Director for Strategic Initiatives, Huck Institutes of the Life Sciences; Huck Distinguished Chair in Global Health; Professor of Microbiology and Infectious Diseases
The basic mechanisms by which pathogenic microbes successfully infect, colonize, and cause disease in their hosts.
Assistant Research Professor of Global Health
Global health security, infectious diseases, and host-pathogen dynamics, as well as expertise in the enhancement of capabilities in the Low- and Middle-Income Countries, including Tanzania and India.
Professor, Veterinary & Biomedical Sciences; Director, Animal Resource Program
The pathogenesis of infectious disease: examining bacterial virulence and associated pathology in relation to host immune responses.
Lester Earl and Veronica Casida Career Development Professor of Food Safety; Assistant Professor of Food Science
Integrating epidemiological, microbiological, molecular and omics methods to better understand microbial pathogenic potential, antimicrobial resistance, and epidemiology of foodborne pathogens.
Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions
Assistant Professor of Biology
Ecological and evolutionary genomics, genetic and ecophysiological basis of adaptation to environmental stress, evolutionary ecology of biological complexity.
Professor of Architecture
My research work represents an expertise in whole systems dynamics contributing to a greater understanding of health, disease spread, design and the built environment. My design research embraces an intentional theoretical underpinning, that of Complexity and General Systems Theory (GST). Thinking in complexity is an essential framework for comprehending the capacity of huge numbers of unique phenomena acting in synergetic relation. Characteristics of complexity explain the nonlinear, indeterminate and irreducible complex systems linking till agriculture to settlement infrastructure to global disease dynamics. GST is the study of the organization of that phenomena in relation. Research interests fall in these main areas: Architecture and building physics Mapping corridors for airborne diseases. This generative mapping identifies potential roles for variables that affect systems behavior (e.g. climate trends, urban density and sprawl, land use management, globalization and trade, seasonal migration and till agricultural production). Designing buildings that limit disease spread. I am currently working with David Hughes on deployable natural systems disease barriers for health care treatment centers in developing countries. Prior work includes systems designs that reduce spread of pathogens (e.g. Avian Influenza) and filter, capture or eradicate other unhealthy emissions from poultry agricultural production facilities with faculty from agricultural engineering and mechanical engineering. Characterizing and modeling dynamic systems behavior Asset mapping. We determine the natural assets of human communities and their environments, and identify those factors and interactions that increase the sustainability and resiliency of the communities. 3D Dynamic Data Modeling. Represents real-time dynamic data from the field (that can be archived in a database) using a graphical algorithm editor tightly integrated with a 3D modeling tool. Game theoretic feedback and General Systems relational strategies This work uses Game Theory tools not frequently employed in traditional architectural investigations along with the relational strategies of General Systems Theory. Together these theories allow us to investigation the relational feedbacks between environments we share in common, the institutions invested in those shared environments and the human individual or collective behavior. For a closer look at a range of research activity and coursework see http://www.policyspace.info
Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).
Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.
Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.
Assistant Professor of Biochemistry and Molecular Biology
How bacteria adapt to a host environment. The mutualistic symbiosis established between the Hawaiian bobtail squid (Euprymna scolopes) and a bioluminescent bacterium (Vibrio fischeri).
Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Anthropology and Biology
Anthropological genomics, paleogenomics, human body size evolution, parasite evolution, and evolutionary medicine.
Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.
Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology
The ecology and evolutionary genetics of infectious disease.
Director of the Center for Neural Engineering; Brush Chair Professor of Engineering; Professor of Neurosurgery; Professor of Engineering Science and Mechanics
Neural engineering, neurosurgery, epilepsy, Parkinsons Disease, wave mechanics, brain machine interfaces, EEG, electrical fields, and control theory.
Assistant Professor of Veterinary and Biomedical Sciences
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research
Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.
Professor of Biology
I am a Biomathematican and very recently moved to Penn State from Georgia Tech (I also had appointments at Emory in Public Health and PBEE). Bacteria and their viruses (phages) provide a way to study ecological and evolutionary processes in real time under the well-controlled laboratory conditions. Many of the questions that our group studies lie at the intersection of fundamental science and improving human and animal health. We develop new approaches to mathematical modeling to better understand the role of the physical structure in how bacteria grow and evolve. To complement this computational work, we work closely with microbiologists, biochemists, virologists, physicians, veterinarians, etc. and combine mathematical models with experiments. In recent years I have taught courses in virus dynamics, population genetics, dynamics and bifurcations, advanced linear algebra, and stochastic processes.