People: Cardiovascular Regulation And Disease
Professor of Kinesiology
Dr. Alexander utilizes in vivo and in vitro approaches using the human cutaneous circulation to examine the underlying signaling mechanisms mediating microvascular dysfunction with primary human aging, hypercholesterolemia, and essential hypertension.
Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.
Associate Director of the Neuroscience Institute; Huck Distinguished Associate Professor of Neural Engineering and Neurosurgery
Role of blood flow and cerebrospinal fluid movement in the development of neurodegenerative diseases, control of cerebral blood flow, neurovascular coupling.
Director of Graduate Training Initiatives; Chair, Intercollege Graduate Degree Program in Integrative and Biomedical Physiology; Professor of Physiology and Kinesiology
My research is focused on aging, post-menopausal women, and cardiac ischemia reperfusion injury using animal models. We are particularly interested in the effects of estrogen deficiency on mitochondrial regulation of cell survival following myocardial infarction. Multiple levels of inquiry addressing mitochondrial quality control regulation and immune signaling is emphasized.
Professor of Biomedical Engineering and Surgery
Understanding the native cardiovascular system fluid mechanics; understanding the diseased cardiovascular system fluid mechanics, and the impact that cardiovascular prosthetics generate during and post implantation.
Associate Professor of Nutritional Sciences
We seek to understand disease-related functional changes in the context of global changes in lipid mediators (bioactive metabolites of dietary fatty acids) and use them to identify markers of disease and better ways to prevent or manage disease