Workshop Day 3: Structural and Biophysical Methods in Biomolecular Research

X-Ray Crystallography, Scattering and Biomolecular Interactions Core Facilities

Day 3 Schedule

Zoom:

9:00 a.m. - From single molecules to biomolecular condensates: applications of optical tweezers in chromatin biology; Jia Gao, grad student, Lee Lab, Dept. of Chemistry

9:15 a.m. - Delineateing the conformational landscape of the Picornavirus 3CD Protein using small angle x-ray scattering; Mohammad Hasan, grad student, Boehr Lab, Dept. of Chemistry

9:30 a.m. - When AI meets the lab: Integrating AphaFold, molecular dynamics and biophysical methods; Ibrahim Moustafa, asst research professor, Biomolecular Interactions & X-ray Crystallography & Scattering Cores, Dept. of Biochem & Mol. Biology

10:15 a.m. - Probing macromolecular interactions using multi-wavelength analytical ultracetrifugation and small angle x-ray scattering; Neela Yennawar, director, Biomolecular Interactions & X-ray Crystallography & Scattering Cores, Huck Institutes

11:00 a.m. - X-ray crystallography 3D structures at atomic resolution, Hemant Yennawar, co-director, X-ray Crystallography & Scattering Core, Huck Institutes

8 Althouse Lab:

1:00 p.m. - Using exclusion chromatography coupled with multi-angle light scattering and dynamic light scattering to measure accurate molar mass and hydrodynamic radius of bovine serum albumin; Julia Fecko, research technologist, Biomolecular Interactions & X-ray Crystallography & Scattering Cores, Huck Institutes

2:00 p.m. - UltraScan III analytical ultracetrifugation software for AUC data collection and analysis, SAXSlab and ATSAS software for Bio-SAXS data collection and analysis; Neela Yennawar, director, Biomolecular Interactions & X-ray, Crystallography & Scattering Cores, Huck Institutes

3:00 p.m. - Single crystal diffractometer - data collection, structure solution demonstration; Hemant Yennawar, co-director, X-ray Crystallography & Scattering Core, Huck Institutes

Contact

  Neela Yennawar
  nhy1@psu.edu