Proteomics and Mass Spectrometry Core Facility

Waters Q-TOFQuadrupole Time-of-Flight (TOF) Spectrometer

Waters Q-TOFQuadrupole Time-of-Flight (TOF) Spectrometer
Waters Q-TOFQuadrupole Time-of-Flight (TOF) Spectrometer

The Waters Q-TOF Premier is a Quadrupole Time-of-Flight (TOF) tandem mass spectrometer coupled to a quaternary HPLC system.

Uses

  • Capable of a variety of ionization options that can apply to a range of compound classes, from small organic molecules to intact proteins of 60kD or more
  • Quaternary HPLC allows for isocratic or gradient elution for chromatographic separations

Details

  • Delivers high sensitivity, resolution, and exact mass measurements for LC/MS applications.
  • High resolution gives the selectivity needed to separate analyte spectra from interferences and background chemical noise.
  • High sensitivity helps to achieve very low detection limits.
  • Exact mass measurements of small molecules give the elemental composition information that can be used to identify these analytes.