Thermo Orbitrap Astral

Orbitrap Astral Mass Spectrometer

The performance characteristics of this instrument make it ideally suited for accurate and precise quantitation at an unprecedented depth of coverage and higher throughput

Orbitrap Astral Mass Spectrometer

Uses

  • Global metabolomics
  • Global lipidomics
  • Isotope-tracing
  • Small compound identifications

Specifications

  • High resolution quadrupole mass filter, Orbitrap mass analyzer and a Astral mass analyzer
  • Maximum Orbitrap mass analyzer resolution of up to 480,000 FWHM at m/z 200
  • Maximum Astral mass analyzer resolution up to 80,000 FWHM at m/z 524
  • MS/MS acquisition rates of up to 40 Hz with 7,500 resolution at m/z 200 for the Orbitrap mass analyzer
  • MS/MS acquisition rates of up to 200 Hz in the Astral mass analyzer with 80,000 resolution at m/z 524
  • Mass Range: Standard mass range of m/z 40–6,000
  • Orbitrap Mass Accuracy: <3ppm RMS drift (external calibration over 24 hours)
  • Astral Mass Accuracy: <5 ppm RMS drift (external calibration over 24 hours)
  • Orbitrap Dynamic Range: >5,000 within a single microscan
  • Astral Dynamic Range: >1,000 within a single microscan
  • MS/MS Electrospray Ionization (ESI) Orbitrap Sensitivity: MS/MS: 50 fg reserpine on column S/N 100:1 SIM: 50 fg reserpine on column S/N 150:1

Details

Please contact the Metabolomics Core Director, Ashley Shay, for more information.

Acknowledgement

All work performed in any of the Huck Institutes of the Life Sciences’ shared facilities should be acknowledged in scholarly reports, presentations, posters, papers, and all other publications. Proper acknowledgment provides a visible measure of the impact of the Huck Institutes’ shared facilities and is essential for our continued funding. Please refer to "Acknowledgment & Co-authorship" section under "Get Started" for more information.