Uses
- Global metabolomics and lipidomics
- Elucidate positional isomers on small molecules and lipids
- Gain significant sensitivity and discover less abundant ions
- SWATH DIA, Improved DDA and MRMHR
Specifications
- Zeno trap provides an increase to ≥90% duty cycle across the entire mass range for MS/MS acquisition modes (Zeno IDA and Zeno MRMHR)
- MS/MS sensitivity improvements from 4-20x
- Reagent-free and tunable, high-efficiency electron activated dissociation (EAD) fragmentation in the EAD cell, offering alternative fragmentation for both small and large molecules workflows
- New levels of specificity with various electron-based
Details
Dissociation techniques
- Richer fragmentation for improved structural information.
- Greater than 5 orders of inter-scan linear dynamic range and 4 orders of intra-scan linear dynamic range in both MS and MS/MS modes
- MS/MS scan rates up to 133 Hz
- Mass range: 40 - 40,000 Da
- Resolution: >42K at m/z 956
- Mass accuracy: <2ppm RMS ext, <1 ppm RMS int
Acknowledgement
Users of this instrument are required to acknowledge the Huck Institutes’ Metabolomics Core Facility (RRID: SCR_023864) in any resulting publications. Please review the acknowledgment and co-authorship guidelines for full details.