MicroCal Auto-iTC200

MicroCal Auto-iTC200
Woman working with MicroCal Auto-iTC200

The Auto-iTC200 combines the performance of the most sensitive isothermal titration calorimeter available with full automation.


  • Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules
  • Enzyme kinetics
  • Assessment of molecular structure changes on binding mechanisms


  • Operating temperature: 2°C to 80°C
  • Sample storage temperature: 4°C to ambient
  • Response time: 10 seconds
  • Cell design: 200µl coin-shaped
  • Titration syringe: 40µl
  • Usable syringe volume: 38µl
  • Smallest injection size: 0.1µl
  • Stirring speed: 500-1,500 rpm

Equipment Location

Automated Calorimetry Facility


Contributions made by data from this instrument may be acknowledged in papers with language similar to the example below:

We would like to acknowledge Dr. Neela Yennawar and Julia Fecko from the Pennsylvania State University Automated Biological Calorimetry facility for use of Auto ITC200 – NSF-MRI award DBI-0922974 (Bevilacqua et al 2009).