The Huck Institutes of the Life Sciences

Center for Molecular Investigation of Neurological Disorders News

Noteworthy news pertaining to the Center for Molecular Investigation of Neurological Disorders

Center for Molecular Investigation of Neurological Disorders News

New strategy for antidepressant therapies

Increasing the activity of the neurotransmitter GABA in the brains of depressed mice has antidepressant effects

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Modern brain circuitry retains ancient foundation

Studying sea anemones' molecular nerve-signaling machinery, Tim Jegla finds that a burst of evolutionary innovation laid the foundation of our nervous systems more than half a billion years ago.

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Crowd-funding campaign to accelerate clinical trials of brain-repair discovery

Pushing promising new brain-repair research from the Gong Chen lab into clinical trials is the goal of a quick crowd-funding campaign that kicked off March 30.

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Nerve-cell signaling traced back to common ancestor of humans and sea anemone

New research led by by Tim Jegla shows that a burst of evolutionary innovation in the genes responsible for electrical communication among nerve cells in our brains occurred over 600 million years ago in a common ancestor of humans and the sea anemone.

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Ben Franklin's TechCelerator turns promising research into startups with promise

Research-to-startup program helps build entrepreneurship among scientists including Huck Institutes faculty researchers Tony Jun Huang and Gong Chen.

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Rescue of Alzheimer's memory deficit achieved by reducing 'excessive inhibition'

A new drug target to fight Alzheimer's disease has been discovered by a research team led by Gong Chen, a Professor of Biology and the Verne M. Willaman Chair in Life Sciences at Penn State University.

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Quantifying the genomic variation of herpes viruses is a crucial step toward a vaccine

A new study by Huck Institutes faculty researcher Moriah Szpara and an international team of scientific collaborators begins the process of quantifying variation between the genomes of all known strains of herpes simplex virus (HSV) a crucial step toward developing an effective vaccine.

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Experiments show hypothesis of microtubule steering accurate

Tiny protein motors in cells can steer microtubules in the right direction through branching nerve cell structures, according to Huck Institutes faculty researchers Melissa Rolls and Will Hancock and graduate student Yalei Chen.

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A new pathway for neuron repair is discovered

Penn State University molecular biologists including Huck Institutes faculty member Melissa Rolls and graduate students Richard Albertson, Michelle Stone, and Li Chen have discovered a brand-new pathway for repairing nerve cells that could have implications for faster and improved healing.

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Breakthrough could one day help sufferers of brain injury, Alzheimer's disease

Penn State researchers including Huck Institutes faculty member Gong Chen and graduate students Ziyuan Guo, Yuchen Chen, and Fan Wang have developed an innovative technology to regenerate functional neurons after brain injury and also in model systems used for research on Alzheimer's disease.

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Protein changes linked to symptoms of Alzheimer's Disease

A research discovery that helps point the way to potential therapies for memory-related disorders including Alzheimer's Disease has been made by a team of neuroscientists that includes Huck Institutes affiliate Douglas Cavener.

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Gong Chen selected as holder of the Verne M. Willaman Chair in the Life Sciences

Gong Chen, a professor of biology at Penn State, has been appointed as Holder of the Verne M. Willaman Chair in the Life Sciences effective July 1, 2013 in recognition of his national and international reputation for excellence in research and teaching.

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Huck Institutes seek new Associate Directors for positions in science leadership

The Huck Institutes wish to appoint a series of new Associate Directors to work with the management team and help in developing new initiatives.

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Unique pathogen requires a novel approach to studying virulence

Huck Institutes researcher Moriah Szpara takes an interdisciplinary tack in her work -- using tools from neurobiology, virology, bioinformatics, and comparative genomics to find keys to a cure for human herpesvirus.

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Alzheimer's, schizophrenia, and autism now can be studied with mature brain cells reprogrammed from skin cells

A research team led by Huck Institutes affiliate Gong Chen has developed a new method for obtaining mature neurons from reprogrammed skin cells, allowing difficult-to-study diseases such as Alzheimer's, schizophrenia, and autism to be probed more safely and effectively.

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Autism linked to increased genetic change in regions of genome instability

Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery by a team of scientists that includes Huck Institutes affiliates Scott Selleck, Marylyn Ritchie, and Santhosh Girirajan.

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Nine Huck Institutes faculty members featured in Discovery U videos

Peter Hudson, Scott Selleck, David Hughes, Melissa Rolls, Paula Droege, Tracy Langkilde, Phil Bevilacqua, Stephen Schaeffer, and Robert Paulson talk about research that's driving scientific discovery at Penn State.

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Yingwei Mao receives two major grants

The American Heart Association and the Brain & Behavior Research Foundation have each awarded Dr. Mao with a grant intended to provide support for promising beginning scientists.

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Luscher advisees awarded at Undergraduate Research Exhibition

Vladimir Khristov and Garret Cheung, two undergraduate students advised by Beni Luscher, took second prize in the life and health sciences category.

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Luscher advisees awarded at Undergraduate Research Exhibition

Vladimir Khristov and Garret Cheung " two undergraduate students advised by Beni Luscher " took second prize in the life and health sciences category.

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