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Center for Eukaryotic Gene Regulation - News

Noteworthy news pertaining to the Center for Eukaryotic Gene Regulation

Center for Eukaryotic Gene Regulation News

Five Penn State professors honored with Faculty Scholar Medals

Huck-cofunded faculty researcher Song Tan is among the awardees.

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First detailed picture of a cancer-related cell enzyme in action on a chromosome

A landmark study by Huck faculty researcher Song Tan provides new insight into the function of an enzyme related to the BRCA1 breast cancer protein.

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Evan Pugh Professorships awarded to three Huck Institutes faculty

Nina Jablonski, B. Franklin Pugh, and Andrew Read have been named Evan Pugh Professors, the highest distinction bestowed by the University on its faculty.

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Scientists discover the origins of genomic "dark matter"

A duo of Penn State scientists that includes Huck Institutes affiliate B. Franklin Pugh has achieved a major milestone in understanding how genomic "dark matter" originates.

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Short-term gene-expression "memory" is inherited in proteins associated with DNA

By studying a gene in yeast, a team of scientists led by Huck Institutes affiliate Lu Bai has found that modifications to proteins associated with DNA can control whether or not a gene is allowed to function and may be important in maintaining a gene's "expression potential" so that future cells will behave as the parent cell did.

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Huck Institutes seek new Associate Directors for positions in science leadership

The Huck Institutes wish to appoint a series of new Associate Directors to work with the management team and help in developing new initiatives.

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Gene offers clues to new treatments for a harmful blood clotting disorder

A research team led by Huck Institutes affiliate Yanming Wang and Harvard's Denisa Wagner finds a gene that could offer new insights into treatment strategies for the harmful blood clots of deep-vein thrombosis.

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A strategy is discovered to activate genes that suppress cancer

A team of researchers led by Yanming Wang of the Huck Institutes' Center for Eukaryotic Gene Regulation and Gong Chen of the Department of Chemistry has found that by inhibiting the PAD4 enzyme they can reactivate tumor-suppressing genes to destroy cancerous cells.

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Huck Institutes to host 2nd Annual Bioinformatics and Genomics Retreat - September 16th & 17th, 2011

Keynote speaker Dr. Richard Edward Green. Visionary talk and panel discussion. Poster sessions. Research presentations. Open to all Penn State faculty, postdocs, students, and staff. Registration is free!

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Computations 19x faster with new adaptive algorithm

Researchers using a new algorithmic process for a heuristic embedding strategy they call "Adaptive GDDA-BLAST" can now see the results of their computations 19 times faster than with their previous computational method. The new method has the added benefits of detecting structural homology in highly divergent protein sequences and isolating secondary structural elements of transmembrane and ankyrin-repeat domains, with possibly wide-ranging impacts on human health and disease studies.

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Scientists capture first-ever atomic view of key genetic processes

Using a 3-D visualization method called X-ray crystallography, Song Tan, associate professor of biochemistry and molecular biology has built the first-ever image of a protein interacting with the nucleosome -- DNA packed tightly into space-saving bundles organized around a protein core. The research, performed at the Penn State Center for Eukaryotic Gene Regulation of the Huck Institutes, is expected to aid future investigations into diseases such as cancer.

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Faculty appointments in systems and computational genomics

We seek computer and information scientists, social scientists, life scientists, physicists, mathematicians, statisticians and biomedical researchers interested in analyzing genomic data, undertaking systems and functional genomics and in applying these results to a broad range of biological problems.

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