The Huck Institutes of the Life Sciences

Thomas lab

Claire Thomas' lab studies the cortical spectrin/F-actin cytoskeleton and its role in the control of cell polarity, adhesion and vesicular trafficking.
spectrins in the fly embryo

spectrins in the fly embryo

The Thomas lab uses a multidisciplinary approach in Drosophila to study the role of the cortical spectrin skeleton in morphogenesis, cell shape and protein trafficking. Spectrins are large alpha-helical proteins that can organize membranes into domains. We are focusing on the function of b[Heavy]-spectrin, which plays an important role in epithelial cell polarity.