The Huck Institutes of the Life Sciences

Santy lab

Lorraine Santy's lab investigates small GTPase regulation of epithelial cell migration.
cell scattering by ARNO expression

cell scattering by ARNO expression

In the Santy lab we use a cell culture model system to study how small GTPases regulate cell motility. Right now we are focusing on: 1. ARF6 regulation of cell shape and migration, 2. subcellular localization of GTPase activation, 3. crosstalk between small GTPases during migration, and 4. ARF6 regulation of adhesion protein trafficking.