The Huck Institutes of the Life Sciences

Nader Lab

The Nader lab studies skeletal and cardiac muscle size control with a focus on the cellular and molecular mechanisms regulating ribosome biogenesis.
Arabidopsis cell wall

Myotubes

The Nader Lab is focused on elucidating the mechanisms controlling ribosomal RNA synthesis during skeletal and cardiac muscle hypertrophy. Specifically, we are studying ribosomal DNA gene activation at the transcriptional and epigenetic levels. Our objective is to determine how these mechanisms contribute to the development of muscle hypertrophy, how they are dysregulated during pathological states, and how we can manipulate them for therapeutic purposes.