Making steps toward the realization of personalized genomic medicine, Huck Institutes affiliates at the Center for Medical Genomics are finding and analyzing hotspots of genomic instability and mutation known as microsatellites.
A research team led by Huck Institutes affiliate Yanming Wang and Harvard's Denisa Wagner finds a gene that could offer new insights into treatment strategies for the harmful blood clots of deep-vein thrombosis.
Scientists including Huck Institutes affiliates George Perry and Webb Miller lead a research team that for the first time has sequenced and analyzed the complete genomes of three separate populations of aye-ayes in an effort to help guide conservation.
Peter Hudson, Scott Selleck, David Hughes, Melissa Rolls, Paula Droege, Tracy Langkilde, Phil Bevilacqua, Stephen Schaeffer, and Robert Paulson talk about research that's driving scientific discovery at Penn State.
A team of researchers led by Yanming Wang of the Huck Institutes' Center for Eukaryotic Gene Regulation and Gong Chen of the Department of Chemistry has found that by inhibiting the PAD4 enzyme they can reactivate tumor-suppressing genes to destroy cancerous cells.
Dr. Bevilacqua, a professor of chemistry at Penn State and co-director of the Huck Institutes' Center for RNA Molecular Biology, has been honored by the Eberly College of Science Alumni Society with the 2012 C.I. Noll Award for Excellence in Teaching.
Researchers using a new algorithmic process for a heuristic embedding strategy they call "Adaptive GDDA-BLAST" can now see the results of their computations 19 times faster than with their previous computational method. The new method has the added benefits of detecting structural homology in highly divergent protein sequences and isolating secondary structural elements of transmembrane and ankyrin-repeat domains, with possibly wide-ranging impacts on human health and disease studies.
We seek computer and information scientists, social scientists, life scientists, physicists, mathematicians, statisticians and biomedical researchers interested in analyzing genomic data, undertaking systems and functional genomics and in applying these results to a broad range of biological problems.