Grant to help pave a big data highway to explore genome, enhance health
A $6.1 million, five-year grant from the National Institute of Diabetes, Digestive and Kidney Diseases at the National Institutes of Health may help researchers leverage massive amounts of genomic data to develop medical treatments and pharmaceuticals, according to an international team of researchers.
Five Penn State professors honored with Faculty Scholar Medals
Huck-cofunded faculty researcher Song Tan is among the awardees.
Paul Medvedev receives National Science Foundation CAREER award
NSF award will provide funding for Medvedev to develop algorithms for big genomic data
Penn State and Geisinger announce new collaborative gene research project
Marylyn Ritchie, professor of biochemistry and molecular biology and director of the Center for Systems Genomics in the Huck Institutes of the Life Sciences at Penn State University, will lead a collaborative effort between Penn State and Geisinger Research to connect the genome data of 100,000 anonymous patients with their medical histories, in order to identify the genetic and environmental basis of human disease.
New video profile: Marta Byrska-Bishop
Marta Byrska-Bishop -- a Ph.D. candidate in the Huck Institutes' Molecular, Cellular, and Integrative Biosciences program -- studies genomics and gene regulation in relation to inherited diseases.
Living African group discovered to be the most populous humans over the last 150,000 years
New genetic research reveals that a small group of hunter-gatherers now living in Southern Africa once was so large that it comprised the majority of living humans during most of the past 150,000 years.
Major new study reveals new similarities and differences between mice and humans
Powerful clues have been discovered about why the human immune system, metabolism, stress response, and other life functions are so different from those of the mouse.
Video profile: Marta Byrska-Bishop & Ross Hardison
Molecular, Cellular, and Integrative Biosciences Ph.D. candidate Marta Byrska-Bishop and faculty researcher Dr. Ross Hardison study genomics and gene regulation in relation to inherited diseases.
Human heart beats using nearly billion-year-old molecular mechanism
Neurobiologist Tim Jegla and his Lab find in a living, ancient sea anemone species the same gene family and ion channel that regulate the slow wave contractions of the human heart.
Existence of new neuron repair pathway discovered
The Rolls Lab discovers a new neuron repair pathway that could one day help people suffering from nerve damage.
Modernizing malaria research through a new, interdisciplinary approach to parasitology
Huck Institutes faculty researcher Manuel Llinas uses cutting-edge techniques in metabolomics and genomics to try and beat the malaria-causing Plasmodium parasite.
Investigating roles of rare genetic variants in disease
Researchers at the Center for Systems Genomics are developing bioinformatics software to facilitate analysis of rare variation in human genome sequence data.
Turning biologists into programmers
Research by Huck Institutes affiliate Howard Salis demonstrates how synthetic life could create real benefits.
Kateryna Makova honored as Penn State's Francis R. Pentz and Helen M. Pentz Professor of Science
Huck Institutes affiliate Kateryna Makova, a professor of biology at Penn State, has been honored by the University's Eberly College of Science by being appointed the Francis R. and Helen M. Pentz Professor of Science.
Gong Chen selected as holder of the Verne M. Willaman Chair in the Life Sciences
Gong Chen, a professor of biology at Penn State, has been appointed as Holder of the Verne M. Willaman Chair in the Life Sciences effective July 1, 2013 in recognition of his national and international reputation for excellence in research and teaching.
Huck Institutes seek new Associate Directors for positions in science leadership
The Huck Institutes wish to appoint a series of new Associate Directors to work with the management team and help in developing new initiatives.
Unique pathogen requires a novel approach to studying virulence
Huck Institutes researcher Moriah Szpara takes an interdisciplinary tack in her work -- using tools from neurobiology, virology, bioinformatics, and comparative genomics to find keys to a cure for human herpesvirus.
Avocado farmers face unique foe in fungal-farming beetle
Beetles with unusual "green thumbs" for growing fungi are threatening avocado crops and could transform into a more destructive pest, according to an international team of researchers that includes Huck Institutes affiliate David Geiser.
Mathematical models target disease with drugs chosen by your DNA
Medicines that are personally tailored to your DNA are becoming a reality, thanks to the work of U.S. and Chinese scientists including Huck Institutes affiliate Rongling Wu who have developed statistical models to predict which drug is best for a specific individual with a specific disease.
Understanding bulls' gene-rich Y chromosomes may improve herd fertility
Researchers including Huck Institutes affiliate Wansheng Liu have found that, surprisingly, the Y chromosomes of cattle have more genes and are more active than the Y chromosomes of a variety of primates and other mammals.
Genome instability studies could change treatment for cancer and other diseases
Making steps toward the realization of personalized genomic medicine, Huck Institutes affiliates at the Center for Medical Genomics are finding and analyzing hotspots of genomic instability and mutation known as microsatellites.
Gene offers clues to new treatments for a harmful blood clotting disorder
A research team led by Huck Institutes affiliate Yanming Wang and Harvard's Denisa Wagner finds a gene that could offer new insights into treatment strategies for the harmful blood clots of deep-vein thrombosis.
Endangered lemurs' complete genomes are sequenced and analyzed for conservation efforts
Scientists including Huck Institutes affiliates George Perry and Webb Miller lead a research team that for the first time has sequenced and analyzed the complete genomes of three separate populations of aye-ayes in an effort to help guide conservation.
Engineering Biofilms: Understanding how bacteria function in communities could lead to a host of new applications
From oil-spill clean-up to producing alternative fuels, microbial communities have the potential to do great good. Professor Tom Wood is determined to figure out how.
Craig E. Cameron appointed the Eberly Family Chair in Biochemistry and Molecular Biology
Craig E. Cameron, a professor of biochemistry and molecular biology at Penn State, has been appointed the Holder of the Eberly Family Chair in Biochemistry and Molecular Biology.
Nine Huck Institutes faculty members featured in Discovery U videos
Peter Hudson, Scott Selleck, David Hughes, Melissa Rolls, Paula Droege, Tracy Langkilde, Phil Bevilacqua, Stephen Schaeffer, and Robert Paulson talk about research that's driving scientific discovery at Penn State.
Sarah Assmann invited to write Coulter Review paper for the International Journal of Plant Sciences
This inaugural Coulter Review article is scheduled for publication in the January 2013 issue of the International Journal of Plant Sciences.
Scott Showalter receives the inaugural Eastern Analytical Society New Faculty Award in NMR Spectroscopy
The award recognizes outstanding contributions by new faculty to the development of the field of nuclear magnetic resonance (NMR) spectroscopy.
Penn State is awarded a $5.8 million grant to expand its Galaxy biomedical analysis software
Anton Nekrutenko of the Center for Comparative Genomics and Bioinformatics, with co-developer James Taylor of Emory University, will continue to build new functionality into the Galaxy resource.
A strategy is discovered to activate genes that suppress cancer
A team of researchers led by Yanming Wang of the Huck Institutes' Center for Eukaryotic Gene Regulation and Gong Chen of the Department of Chemistry has found that by inhibiting the PAD4 enzyme they can reactivate tumor-suppressing genes to destroy cancerous cells.
Philip C. Bevilacqua is awarded the C.I. Noll Award for Excellence in Teaching
Dr. Bevilacqua, a professor of chemistry at Penn State and co-director of the Huck Institutes' Center for RNA Molecular Biology, has been honored by the Eberly College of Science Alumni Society with the 2012 C.I. Noll Award for Excellence in Teaching.
College of Medicine researchers featured in recent media
Huck Institutes faculty members Wafik El-Deiry, James Broach and Xuemei Huang have each been featured in recent Penn State publications.
Huck Institutes' faculty member overturns nearly half a century of erroneous science
Dr. Donald Bryant and his research team discover genes coding for complete TCA cycle in cyanobacteria
Huck Institutes' faculty member recognized in international interdisciplinary publications
Recent papers in Nature feature the collaborative interdisciplinary work of international scientists and Penn State professor Beth Shapiro
Former Huck Institutes director in New York Times
Dr. Nina Fedoroff, "Engineering Food for All."
Computations 19x faster with new adaptive algorithm
Researchers using a new algorithmic process for a heuristic embedding strategy they call "Adaptive GDDA-BLAST" can now see the results of their computations 19 times faster than with their previous computational method. The new method has the added benefits of detecting structural homology in highly divergent protein sequences and isolating secondary structural elements of transmembrane and ankyrin-repeat domains, with possibly wide-ranging impacts on human health and disease studies.
Faculty appointments in systems and computational genomics
We seek computer and information scientists, social scientists, life scientists, physicists, mathematicians, statisticians and biomedical researchers interested in analyzing genomic data, undertaking systems and functional genomics and in applying these results to a broad range of biological problems.