The Huck Institutes of the Life Sciences

Automated Biological Calorimetry Facility Applications

Selected research done at the Automated Biological Calorimetry Facility at University Park
Spectrin tetramer formation is not required for viable development in Drosophila
Khanna MR, Mattie FJ, Browder KC, Radyk MD, Crilly SE, Bakerink KJ, Harper SL, Speicher DW, Thomas GH, (2015) BiolChem, 290(2), 706-15
Efficient Delivery of Long-Chain Fatty Aldehydes from the Nostoc punctiforme Acyl–Acyl Carrier Protein Reductase to its Cognate Aldehyde Deformylating Oxygenase
Warui, D., Pandelia, M.E., Rajakovich, L., Krebs, C., Bollinger, J.M., Booker, S., (2014) Biochemistry. 10.1021/bi500847u
Thermodynamic and Structural Determinants of Differential Pdx1 Binding to Elements from the Insulin and IAPP Promoters
Bastidas M., Showalter S., (2013) Journal of Molecular Biology. Vol. 425, Issue 18, p.3360-3377
Functional significance of evolving protein sequence in dihydrofolatereductase from bacteria to humans
C. Tony Liu, Philip Hanoian, Jarrod B. French, Thomas H. Pringle, Sharon Hammes-Schifferand, Stephen J. Benkovic(2013) PNAS, vol. 110 no. 25, 10159-10164.
Mechanistic characterization of the 5'-triphosphate-dependent activation of PKR: Lack of 5'-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD
Toroney, R., Hull, C. M., Sokoloski, J. E., and Bevilacqua, P. C. (2012) RNA 18, 1862-1874.
Specificity of the Double-Stranded RNA-Binding Domain from the RNA-Activated Protein Kinase PKR for Double-Stranded RNA: Insights from Thermodynamics and Small-Angle X-ray Scattering
Patel, S., Blose, J. M., Sokoloski, J. E., Pollack, L., and Bevilacqua, P. C. (2012) Biochemistry 51, 9312-9322.
CsrA-FliW interaction governs flagellin homeostasis and a checkpoint on flagellar morphogenesis in Bacillus subtilis
Mukherjee, S., Yakhnin, H., Kysela, D., Sokoloski, J., Babitzke, P., and Kearns, D. B. (2011) MolMicrobiol 82, 447-461