The Huck Institutes of the Life Sciences

Aging, Exercise and Muscle Biology

Two adults lifting weights

Research being done by Physiology graduate program faculty in the area of aging, exercise and muscle physiology


About aging, exercise and muscle research

Research on aging has reached the exciting stage of new insights regarding cellular pathways which appear to modulate both longevity and health. Current research is focused on characterizing mechanisms involved in promoting healthspan, rather than lifespan extension. Many of our faculty utilize models of human and animal aging, as well as exercise as a stressor to illuminate physiological mechanisms of health and disease. Use of exercise as an intervention to promote healthspan and muscle growth is also emphasized.

Potential specialization areas

  • Post-menopausal estrogen deficiency on cardiovascular function
  • Heterogeneity in genetically manipulated phenotypes
  • Muscle Bone interactions
  • Mechanisms of skeletal muscle hypertrophy
  • Caloric restriction



W. Larry Kenney
Professor of Physiology and Kinesiology

Environmental and exercise physiology, particularly human thermoregulation, skin blood flow, and the biophysics of heat exchange.
Donna Korzick
Professor of Physiology and Kinesiology
Chair, Intercollege Graduate Degree Program in Physiology

Effects of chronic endurance exercise and senescence on the regulation of cardiovascular function. Ischemia/reperfusion injury and the role of non-genomic estrogen receptor signaling in the aged female rat heart.
James Marden
Professor of Biology
Director of Operations, Huck Institutes of the Life Sciences

Gustavo Nader
Assoc. Professor, Kinesiology

Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.
David Proctor
Professor of Kinesiology, Physiology, and Medicine

Physiology of aging and exercise; cardiovascular responses to exercise; regulation of skeletal muscle blood flow; skeletal muscle adaptation; vascular adaptation.
Jonas Rubenson
Assoc. Professor, Kinesiology

Integrating experimental and modeling approaches to study gait and skeletal muscle function during locomotion in both health and disease/impairment. In particular, the relationship between in vivo muscle mechanics and metabolic energetics and mechanisms underlying locomotor adaptation and optimization.
Robert L Sainburg
Professor of Kinesiology
Professor of Neurology
Director of Center for Movement Science and Technology

Neural mechanisms underlying control of multijoint arm movements in humans.
Rudolf Schilder
Research Associate Professor

Comparative & ecological physiology of insect and mammalian locomotion