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Genomics Institute

Genomics Institute

Facilitating collaboration between researchers from across Penn State in the areas of bioinformatics, computational genomics, evolutionary genomics, functional genomics, and proteomics
Genomics Institute

The Genomics Institute is promoting collaboration in the following fields:

  • Genomics — the study of organisms' whole genomes (i.e. all the genetic material in an organism), DNA and RNA, including identification of the sequence of bases that make up the genetic material, and elucidation of the physical, functional and evolutionary relationships between different parts of the genome
  • Proteomics — the study of proteins' structure and function, including interactions between proteins
  • Bioinformatics — the management and analysis of the vast amounts of data generated by genomic and proteomic studies, using advanced information science and computing techniques
Recent publications
In vivo observations of a fluorescent protein may spark development of novel cancer treatments
In vivo observations of a fluorescent protein may spark development of novel cancer treatments Using a technique known as Bimolecular Fluorescence Complementation (BiFC), Zhi-Chun Lai and his lab have directly visualized the activation of the Hippo (Hpo) tumor-suppressor pathway in living cells.
Hepatitis C treatment's side effects can now be studied in the lab
Hepatitis C treatment's side effects can now be studied in the lab A research team led by Craig Cameron has developed a means of replicating and observing in Petri dishes and test tubes the adverse side effects of certain hepatitis C medications.
Early-Earth cells are modeled to show how the first life forms might have packaged RNA
Early-Earth cells are modeled to show how the first life forms might have packaged RNA Phil Bevilacqua and his colleagues have developed a chemical model that mimics a possible step in the formation of cellular life on Earth four billion years ago.
News
Gene offers clues to new treatments for a harmful blood clotting disorder
A research team led by Huck Institutes affiliate Yanming Wang and Harvard's Denisa Wagner finds a gene that could offer new insights into treatment strategies for the harmful blood clots of deep-vein thrombosis. Gene offers clues to new treatments for a harmful blood clotting disorder - Full article
Penn State to host international conference on pollinator health
The Center for Pollinator Research — directed by Huck Institutes affiliate Christina Grozinger — will host the second International Conference on Pollinator Biology, Health and Policy, bringing together some of the world's foremost scientists in the field to discuss the latest research aimed at understanding and overcoming challenges to pollinator health. Penn State to host international conference on pollinator health - Full article
Autism linked to increased genetic change in regions of genome instability
Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery by a team of scientists that includes Huck Institutes affiliates Scott Selleck, Marylyn Ritchie, and Santhosh Girirajan. Autism linked to increased genetic change in regions of genome instability - Full article