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People who work in Molecular Toxicology

Faculty

  • Shantu Amin

    • Professor of Pharmacology

    Phone number 717-531-8285 Email address sga3@psu.edu

    Research interests:

    Design and synthesis of agents to study mechanisms of cancer etiology and develop anti-cancer agents.

  • Keith Cheng

    • Professor of Pathology, Biochemistry and Molecular Biology, and Pharmacology
    • Director of Experimental Pathology

    Phone number 717-531-8352 Email address kcheng@psu.edu

    Research interests:

    Cancer genetics; Systems Genetics validation of candidate genes from human genetics; skin color genetics; high-throughput automated whole-body 3D genetic and chemical phenomics at cell resolutions in interdisciplinary teams (physics, engineering, computer engineering, heuristic computer vision, user interfaces); synchrotron microCT imaging; genetics of genomic instability; web-based resources

  • Gary Clawson

    • Professor of Pathology, and Biochemistry and Molecular Biology

    Phone number 717-531-5632 Email address gac4@psu.edu

    Research interests:

    Early changes in carcinogenesis.

  • Dhimant Desai

    • Associate Professor of Pharmacology

    Phone number 717-531-8285 Email address dhd11@psu.edu

    Research interests:

    Structural activity relationship of organic chemopreventive and chemotherapeutic agents against cancers of colon, lung, melanoma, and leukemia

  • Kristin Eckert

    • Associate Professor of Pathology, and Biochemistry and Molecular Biology

    Phone number 717-531-4065 Email address kae4@psu.edu

    Research interests:

    Molecular mechanisms of mutagenesis in human cells as related to cancer. How DNA lesions caused by known carcinogens are processed into mutations by human DNA polymerases.

  • Karam El-Bayoumy

    • Professor of Biochemistry and Molecular Biology
    • Associate Director of Basic Research, Penn State Cancer Institute

    Phone number 717-531-1005 Email address kee2@psu.edu

    Research interests:

    Mechanisms of chemical carcinogenesis (emphasis on agents found in tobacco smoke, environment).

  • Adam Glick

    • Associate Professor, Department of Veterinary and Biomedical Sciences
    • Co-Chair, Molecular Medicine Program

    Phone number 814-865-7170 Email address abg11@psu.edu

    Research interests:

    Analysis of the tumor suppressor and oncogenic roles of Transforming Growth Factor Beta in multistage skin carcinogenesis using novel transgenic and knockout mouse models.

  • Harriet Isom

    • Distinguished Professor of Microbiology and Immunology
    • Professor of Pathology

    Phone number 717-531-8609 Email address hci1@psu.edu

    Research interests:

    Regulation of growth control in hepatocytes.

  • Sagarika Kanjilal

    • Associate Professor of Veterinary Science

    Phone number 814-865-9885 Email address quk13@psu.edu

    Research interests:

    Molecular, genomic, and proteomic investigation of cancer pathways, biomarkers, and targeted
    therapeutics.

  • Mark Kester

    • Professor of Pharmacology

    Phone number 717-531-8964 Email address mkester@psu.edu

    Research interests:

    Regulation of kinase cascades by lipid-derived second messengers.

  • Joshua Lambert

    • Asst. Professor, Food Science

    Phone number 814-865-5223 Email address jdl134@psu.edu

    Research interests:
  • Robert Levenson

    • Professor of Pharmacology

    Phone number 717-531-4545 Email address rlevenson@psu.edu

    Research interests:

    Molecular neurobiology, cell differentiation.

  • Andrea Mastro

    • Professor of Microbiology and Cell Biology

    Phone number 814-863-0152 Email address a36@psu.edu

    Research interests:

    Breast cancer and the immune system.

  • Kathleen M Mulder

    • Professor of Biochemistry and Molecular Biology

    Phone number 717-531-6789 Email address kmm15@psu.edu

    Research interests:

    Cloning and functional analysis of TGF-beta signaling components

  • Chris Mullin

    • Professor of Entomology

    Phone number 814-865-2435 Email address camullin@psu.edu

    Research interests:

    Toxicology of insect-plant interactions. Honey bee ecotoxicology. Mechanisms of insect taste chemoreception. Biopesticide action and resistance. Phytochemical ecology.

  • Curtis Omiecinski

    • Professor of Veterinary & Biomedical Sciences
    • H. Thomas and Dorothy Willits Hallowell Chair
    • Co-chair, Intercollege Graduate Degree Program in Molecular Toxicology

    Phone number 814-863-1625 Email address cjo10@psu.edu

    Research interests:

    “Transcriptional regulation by the nuclear receptors CAR and PXR; molecular genetics of human microsomal epoxide hydrolase.”

  • Andrew Patterson

    • Director/Faculty Oversight, Metabolomics Core Facility (University Park)
    • Assistant Professor of Molecular Toxicology

    Phone number 814-867-4565 Email address adp117@psu.edu

    Research interests:

    Working to define the role of Peroxisome Proliferator-Activated Receptor α (PPARα) in mitochondrial dysfunction associated with drug-induced hepatotoxicity

  • Gary Perdew

    • John T. and Paige S. Smith Professor in Agricultural Sciences

    Phone number 814-865-0400 Email address ghp2@psu.edu

    Research interests:

    Molecular mechanism(s) of toxicity, dioxin-mediated signal transduction, regulation of peroxisome proliferator-activated receptor-mediated gene expression.

  • Jeffrey Peters

    • Distinguished Professor of Molecular Toxicology & Carcinogenesis

    Phone number 814-863-1387 Email address jmp21@psu.edu

    Research interests:

    Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.

  • Sandeep Prabhu

    • Professor, Veterinary and Biomedical Sciences

    Phone number 814-863-8976 Email address ksp4@psu.edu

    Research interests:

    Regulation of immune function by oxidative stress and antioxidants, including selenium. Regulation of HIV transcription by selenium.

  • John Richie

    • Professor, Public Health Sciences & Pharmacology

    Phone number 717-531-5381 Email address jrichie@psu.edu

    Research interests:

    Elucidation of factors that regulate cancer risk, including aging, nutrition, tobacco and race/ethnicity.

  • Gavin Robertson

    • Professor of Pharmacology, Pathology, and Dermatology

    Phone number 717-531-8098 Email address gprobertson@psu.edu

    Research interests:

    Genetic regulation of melanoma development.

  • Arun Sharma

    • Associate Professor of Pharmacology

    Phone number 717-531-0003 ext. 285016 Email address aks14@psu.edu

    Research interests:

    Development of novel cancer chemopreventive & therapeutic agents, and elucidation of their mechanisms of action

  • Thomas Spratt

    • Associate Professor of Biochemistry and Molecular Biology
    • Chair, Chemical Biology option of Integrative Biosciences Graduate Program

    Phone number 717-531-4623 Email address tes13@psu.edu

    Research interests:

    The enzymology of DNA repair and mutagenesis.

  • Chen-Pei David Tu

    • Professor of Biochemistry & Molecular Biology

    Phone number 814-863-2096 Email address unh@psu.edu

    Research interests:

    Gene regulation, structure, and function of glutathione S-transferase systems.

  • Jack Vanden Heuvel

    • Professor of Molecular Toxicology

    Phone number 814-863-8532 Email address jpv2@psu.edu

    Research interests:

    Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.

  • Kent Vrana

    • Elliot S. Vesell Professor and Chair of Pharmacology

    Phone number 717-531-8285 Email address kvrana@psu.edu

    Research interests:

    The potential of human embryonic stem cells in regenerative medicine.

  • Jong Yun

    • Associate Professor of Pharmacology
    • Co-chair, Intercollege Graduate Degree Program in Molecular Toxicology

    Phone number 717-531-1508 Email address jky1@psu.edu

    Research interests:

    Targeting sphingosine kinase in cancer cells; molecular regulation of sphingosine kinase signaling pathways in oncogenesis.

  • Jiyue Zhu

    • Professor of Cellular and Molecular Physiology

    Phone number 717-531-3597 Email address joz1@psu.edu

    Research interests:

    Molecular mechanisms of cellular immortalization and cancers.

Graduate students