People who work in Molecular Toxicology
Faculty
-
Shantu Amin
- Professor of Pharmacology
Phone number 717-531-8285 • Email address sga3@psu.edu
Research interests:Design and synthesis of agents to study mechanisms of cancer etiology and develop anti-cancer agents.
-
Keith Cheng
- Professor of Pathology, Biochemistry and Molecular Biology, and Pharmacology
- Co-director, Bioinformatics and Genomics graduate program
- Director of Experimental Pathology
Phone number 717-531-8352 • Email address kcheng@psu.edu
Research interests:Cancer genetics; Systems Genetics validation of candidate genes from human genetics; skin color genetics; high-throughput automated whole-body 3D genetic and chemical phenomics at cell resolutions in interdisciplinary teams (physics, engineering, computer engineering, heuristic computer vision, user interfaces); synchrotron microCT imaging; genetics of genomic instability; web-based resources
-
Gary Clawson
- Professor of Pathology, and Biochemistry and Molecular Biology
Phone number 717-531-5632 • Email address gac4@psu.edu
Research interests:Early changes in carcinogenesis.
-
Dhimant Desai
- Associate Professor of Pharmacology
Phone number 717-531-8285 • Email address dhd11@psu.edu
Research interests:Structural activity relationship of organic chemopreventive and chemotherapeutic agents against cancers of colon, lung, melanoma, and leukemia
-
Kristin Eckert
- Associate Professor of Pathology, and Biochemistry and Molecular Biology
Phone number 717-531-4065 • Email address kae4@psu.edu
Research interests:Molecular mechanisms of mutagenesis in human cells as related to cancer. How DNA lesions caused by known carcinogens are processed into mutations by human DNA polymerases.
-
Karam El-Bayoumy
- Professor of Biochemistry and Molecular Biology
- Associate Director of Basic Research, Penn State Cancer Institute
Phone number 717-531-1005 • Email address kee2@psu.edu
Research interests:Mechanisms of chemical carcinogenesis (emphasis on agents found in tobacco smoke, environment).
-
Adam Glick
- Associate Professor, Department of Veterinary and Biomedical Sciences
- Co-Chair, Molecular Medicine Program
Phone number 814-865-7170 • Email address abg11@psu.edu
Research interests:Analysis of the tumor suppressor and oncogenic roles of Transforming Growth Factor Beta in multistage skin carcinogenesis using novel transgenic and knockout mouse models.
-
Harriet Isom
- Distinguished Professor of Microbiology and Immunology
- Professor of Pathology
Phone number 717-531-8609 • Email address hci1@psu.edu
Research interests:Regulation of growth control in hepatocytes.
-
Sagarika Kanjilal
- Associate Professor of Veterinary Science
Phone number 814-865-9885 • Email address quk13@psu.edu
Research interests:Molecular, genomic, and proteomic investigation of cancer pathways, biomarkers, and targeted
therapeutics. -
Mark Kester
- Professor of Pharmacology
Phone number 717-531-8964 • Email address mkester@psu.edu
Research interests:Regulation of kinase cascades by lipid-derived second messengers.
-
Robert Levenson
- Professor of Pharmacology
Phone number 717-531-4545 • Email address rlevenson@psu.edu
Research interests:Molecular neurobiology, cell differentiation.
-
Andrea Mastro
- Professor of Microbiology and Cell Biology
Phone number 814-863-0152 • Email address a36@psu.edu
Research interests:Breast cancer and the immune system.
-
Kathleen M Mulder
- Professor of Biochemistry and Molecular Biology
Phone number 717-531-6789 • Email address kmm15@psu.edu
Research interests:Cloning and functional analysis of TGF-beta signaling components
-
Chris Mullin
- Professor of Entomology
Phone number 814-865-2435 • Email address camullin@psu.edu
Research interests:Toxicology of insect-plant interactions. Honey bee ecotoxicology. Mechanisms of insect taste chemoreception. Biopesticide action and resistance. Phytochemical ecology.
-
Curtis Omiecinski
- Professor of Veterinary & Biomedical Sciences
- H. Thomas and Dorothy Willits Hallowell Chair
- Co-chair, Intercollege Graduate Degree Program in Molecular Toxicology
Phone number 814-863-1625 • Email address cjo10@psu.edu
Research interests:“Transcriptional regulation by the nuclear receptors CAR and PXR; molecular genetics of human microsomal epoxide hydrolase.”
-
Andrew Patterson
- Director/Faculty Oversight, Metabolomics Core Facility (University Park)
- Assistant Professor of Molecular Toxicology
Phone number 814-867-4565 • Email address adp117@psu.edu
Research interests:Working to define the role of Peroxisome Proliferator-Activated Receptor α (PPARα) in mitochondrial dysfunction associated with drug-induced hepatotoxicity
-
Gary Perdew
- John T. and Paige S. Smith Professor in Agricultural Sciences
Phone number 814-865-0400 • Email address ghp2@psu.edu
Research interests:Molecular mechanism(s) of toxicity, dioxin-mediated signal transduction, regulation of peroxisome proliferator-activated receptor-mediated gene expression.
-
Jeffrey Peters
- Distinguished Professor of Molecular Toxicology & Carcinogenesis
Phone number 814-863-1387 • Email address jmp21@psu.edu
Research interests:Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.
-
Sandeep Prabhu
- Associate Professor, Veterinary and Biomedical Sciences
Phone number 814-863-8976 • Email address ksp4@psu.edu
Research interests:Regulation of immune function by oxidative stress and antioxidants, including selenium. Regulation of HIV transcription by selenium.
-
John Richie
- Professor, Public Health Sciences & Pharmacology
Phone number 717-531-5381 • Email address jrichie@psu.edu
Research interests:Elucidation of factors that regulate cancer risk, including aging, nutrition, tobacco and race/ethnicity.
-
Gavin Robertson
- Professor of Pharmacology, Pathology, and Dermatology
Phone number 717-531-8098 • Email address gprobertson@psu.edu
Research interests:Genetic regulation of melanoma development.
-
Arun Sharma
- Associate Professor of Pharmacology
Phone number 717-531-0003 ext. 285016 • Email address aks14@psu.edu
Research interests:Development of novel cancer chemopreventive & therapeutic agents, and elucidation of their mechanisms of action
-
Thomas Spratt
- Associate Professor of Biochemistry and Molecular Biology
- Chair, Chemical Biology option of Integrative Biosciences Graduate Program
Phone number 717-531-4623 • Email address tes13@psu.edu
Research interests:The enzymology of DNA repair and mutagenesis.
-
Chen-Pei David Tu
- Professor of Biochemistry & Molecular Biology
Phone number 814-863-2096 • Email address unh@psu.edu
Research interests:Gene regulation, structure, and function of glutathione S-transferase systems.
-
Jack Vanden Heuvel
- Professor of Molecular Toxicology
Phone number 814-863-8532 • Email address jpv2@psu.edu
Research interests:Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.
-
Kent Vrana
- Elliot S. Vesell Professor and Chair of Pharmacology
Phone number 717-531-8285 • Email address kvrana@psu.edu
Research interests:The potential of human embryonic stem cells in regenerative medicine.
-
Jong Yun
- Associate Professor of Pharmacology
- Co-chair, Intercollege Graduate Degree Program in Molecular Toxicology
Phone number 717-531-1508 • Email address jky1@psu.edu
Research interests:Targeting sphingosine kinase in cancer cells; molecular regulation of sphingosine kinase signaling pathways in oncogenesis.
-
Jiyue Zhu
- Assistant Professor of Cellular and Molecular Physiology
Phone number 717-531-3597 • Email address joz1@psu.edu
Research interests:Molecular mechanisms of cellular immortalization and cancers.
