People who work in Immune-mediated diseases

Signal transduction pathways that regulate immune function; in particular, role of Tec family tyrosine kinases in T cells and mast cells. How manipulation of these signals affect immune response in diseases such as allergic asthma.

Cellular and molecular mechanisms underlying stress-induced, neuroendocrine-mediated modulation of the immune response to herpes simplex virus infections.

Vitamin D regulation of autoimmunity, especially inflammatory bowel diseases. Molecular and cellular regulation of host immunity, and regulation by nutrients.

Rhinitis and its effects on sleep and daytime somnolence; allergic rhinitis and asthma.

Mechanisms of cellular injury in the retina which lead to retinopathy, especially factors that change tight junction protein expression. Changes in the neural retina in diabetes.

The role of macrophages and dendritic cells in antigen presentation, antiviral immunity and in chronic inflammation during diabetes.

Evolutionary ecology of host-parasite interactions, particularly virulence, infectiousness, vaccine-driven evolution, and drug and insecticide resistance.

Development and function of gamma/delta T cells, a class of immune cells with various roles in microbial immunity, inflammation regulation and tumor surveillance.