Cancer genetics; Systems Genetics validation of candidate genes from human genetics; skin color genetics; high-throughput automated whole-body 3D genetic and chemical phenomics at cell resolutions in interdisciplinary teams (physics, engineering, computer engineering, heuristic computer vision, user interfaces); synchrotron microCT imaging; genetics of genomic instability; web-based resources
Genomics, bioinformatics, and molecular evolution. Origin and diversification of flowers & developmental pathways. Comparative genomics of plants, organelles, & plant gene families. Genomics and evolution of parasitic plants.
We are interested in understanding how ion channels control signaling in the nervous system. We focus on potassium channel-mediated control of firing threshold and ionic mechanisms involved in the generation and processing of sensory potentials. Our research relies on a combination of mouse genetics, electrophysiology, cell biology and compound screening approaches.
Human and non-human primate evolutionary ecology -- how we have adapted
to our variable or changing environments. Research tools used include
analyses of genomic-scale data, especially genome sequence data.