People who work in Chemical Biology

Design and synthesis of agents to study mechanisms of cancer etiology and develop anti-cancer agents.

Roles of RNA-binding proteins in plant physiology. Plant ribonomics. Identification and characterization of functional RNAs in plants.

Investigation of protein function using structural techniques such as x-ray crystallography.

Structure, function, and regulation of proteolytic enzymes.

To apply synthetic chemistry to create novel carbohydrate and peptide-based molecules and explore their biological and therapeutic functions.

Creation of methods to regulate expression of iron-binding proteins in the nervous system.

Understanding the mechanisms of tobacco carcinogenesis and developing appropriate strategies for cancer chemoprevention.

Investigation of protein function, using a variety of biochemical, genetic and structural techniques including x-ray crystallography.

Understanding the structures and interactions between Plasmodium falciparum and human glycoconjugates that lead to malaria pathogenesis.

Theoretical and computational investigation of chemically and biologically important processes; proton, hydride, and proton-coupled electron transfer reactions; mixed quantum/classical molecular dynamics simulations; development of theoretical and computational methods; applications to reactions in solution and proteins.

Etiology of large granular lymphocyte (LGL) leukemia. Identification of the molecular basis for metastatic disease in colorectal cancer.

Structure, function and regulation of mRNA translation initiation factors.

Endocrinology and transmembrane signalling. Diabetes and insulin resistance.

TGF-beta signal transduction, anti-cancer therapeutics and diagnostics, motor proteins, and intracellular trafficking.

Investigation of polyamine metabolism and DNA repair using protein engineering and x-ray crystallography.

The etiology of carcinogen- and virus-induced cancers.

Genetic regulation of melanoma development.

Investigating the folding, stability and function of proteins using NMR spectroscopy.

Biological role of gangliosides.

Design and synthesis of unnatural substrates to examine the mechanisms of DNA repair and mutagenesis.

Graduate program admissions, applicant questions, student visas, course registration, drop/add, grade changes, Candidacy and Comprehensive Exam paperwork.

Contact regarding admissions to this graduate program, and professional development opportunities for students.

Contact regarding comprehensive exams and thesis defenses for Hershey-based students in the Chemical Biology option of the Integrative Biosciences graduate program.