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Rolls lab
single neuron in a living fly brain
In the Rolls lab we are interested in how neurons generate axons and dendrites with different functions and constituents. To address this problem we focus on the role of cytoskeletal organization and polarized trafficking. Currently, we are working on identifying mechanisms and proteins that control microtubule orientation in neurons, as well as the role of microtubule orientation in polarized trafficking. We use genetics and live imaging in Drosophila to assay to investigate the basic cell biology of neurons in their normal environment.