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Luscher lab
gephyrin and NL-2 in a cultured neuron
In the Luscher lab we use biochemical, immunohistochemical and genetic approaches in cultured neurons and mutant mice to elucidate the structure and function of GABAergic inhibitory synapses. We are also interested in how functional deficits in these synapses contribute to neurological and mental disorders such as anxiety, depression, epilepsy, neuropathic pain and drug addiction.