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X-Ray Crystallography Facility

X-Ray Crystallography Facility

Providing training, assistance and expertise in crystallizing and determining the three-dimensional structures of proteins and other biological macromolecules

Please note: Users with sufficient technical expertise may carry out data acquisition and analysis with minimal assistance from the facility staff.

News
Using a 3-D visualization method called X-ray crystallography, Song Tan, associate professor of biochemistry and molecular biology has built the first-ever image of a protein interacting with the nucleosome -- DNA packed tightly into space-saving bundles organized around a protein core. The research, performed at the Penn State Center for Eukaryotic Gene Regulation of the Huck Institutes, is expected to aid future investigations into diseases such as cancer. Scientists capture first-ever atomic view of key genetic processes - Full article
Training required

Approved users must attend a University-run X-ray safety class before using the instruments.